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Assessment of genetic diversity among Syrian durum (Triticum ssp. durum) and bread wheat (Triticum aestivum L.) using SSR markers

Autor: N. MirAli, A. Kalhout, Marion S. Röder, M. Y. Moualla, S. Achtar

Publikováno v: Russian Journal of Genetics. 46:1320-1326

Genetic diversity among 49 wheat varieties (37 durum and 12 bread wheat) was assayed using 32 microsatellites representing 34 loci covering almost the whole wheat genome. The polymorphic information content (PIC) across the tested loci ranged from 0

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7c0a6d59030818de64599d129cf9fa3
https://doi.org/10.1134/s1022795410110074

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Assessment of genetic diversity among Syrian durum (Triticum turgidum ssp. durum) and bread wheat (Triticum aestivum L.) using SSR markers

Autor: S, Achtar, M Y, Moualla, A, Kalhout, M S, Röder, N, MirAli

Publikováno v: Genetika. 46(11)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4a4e21d1eab2bb4d7319cd338ac7e0df
https://pubmed.ncbi.nlm.nih.gov/21254727

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A randomized phase II p53 vaccine trial comparing subcutaneous direct administration with intravenous peptide-pulsed dendritic cells in high risk ovarian cancer patients

Autor: M. S. Achtar, Seth M. Steinberg, Samir N. Khleif, Carmen Visus, Eva Wieckowski, Theresa L. Whiteside, Malgorzata Czystowska, Jay A. Berzofsky, V. E. Herrin

Publikováno v: Journal of Clinical Oncology. 25:3011-3011

3011 Background: 50% of ovarian cancers carry a p53 mutation, most of which can lead to overexpression of the protein, providing a unique target for vaccine therapy. Preclinical data shows cytotoxic T-lymphocytes can be generated against wild-type pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e68b1f402c8aa74db7e27911477e77f
https://doi.org/10.1200/jco.2007.25.18_suppl.3011

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Phase II clinical trial of mutant Ras peptide vaccine in combination with GM-CSF and IL-2 in advanced cancer patients

Autor: Sarah Bernstein, B. Gause, Antoun Toubaji, M. S. Achtar, Michael Hamilton, R. Berhens, Samir N. Khleif, V. E. Herrin, Frank Grollman

Publikováno v: Journal of Clinical Oncology. 25:3067-3067

3067 Background: Mutant ras oncogenes produce novel proteins that are processed and displayed through HLA molecules on tumor cells. Therefore, mutant ras is an attractive target for vaccine therapy. We have shown in a previous phase I trial that vacc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f25d8db0398bf1b85fe09b9d3260f9f
https://doi.org/10.1200/jco.2007.25.18_suppl.3067

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Immunotherapeutic role of mutant ras peptide-based vaccine as an adjuvant in pancreatic and colorectal cancer

Autor: Samir N. Khleif, Maurizio Provenzano, V. E. Herrin, Sarah Bernstein, Antoun Toubaji, M. S. Achtar, T. B. Brent-Steel, Francesco M. Marincola

Publikováno v: Journal of Clinical Oncology. 23:2573-2573

2573 Background: The ras oncogene is one of the best characterized oncogenes in human cancers; it is frequently mutated by a single amino acid substitution of codon 12. Those mutations are prevalent in many types of cancer including pancreatic adenoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::056e42fde4f59503b876fc5cac22ce6f
https://doi.org/10.1200/jco.2005.23.16_suppl.2573

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Autologous PBMCs pulsed with HPV16 E6 as an immunotherapeutic agent for patients with advanced cervical cancer

Autor: Jay A. Berzofsky, Samir N. Khleif, B. Gause, D. Contoise, Seth M. Steinberg, V. E. Herrin, Frank Grollman, Sarah Bernstein, M. S. Achtar, Ramy Ibrahim

Publikováno v: Journal of Clinical Oncology. 23:2508-2508

2508 Background: Cervical cancer is the second leading cause of cancer deaths amongst women. Despite the success of early discovery, some patients still present with metastatic disease. More than 9...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62811ad8b55c0435a340c621da598105
https://doi.org/10.1200/jco.2005.23.16_suppl.2508

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