Immunotherapy use outside clinical trial populations: never say never?

Autor: Rzeniewicz, K., Larkin, J., Menzies, A.M., Turajlic, S.

Publikováno v: In Annals of Oncology July 2021 32(7):866-880

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Functional antibody and T-cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study.

Autor: Fendler A; Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; Equal contribution., Au L; Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.; Equal contribution., Shepherd STC; Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.; Equal contribution., Byrne F; Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Cerrone M; Tuberculosis Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; Department of Infectious Disease, Imperial College London, W12 0NN, UK., Boos LA; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Rzeniewicz K; Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Gordon W; Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Shum B; Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Gerard CL; Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Ward B; Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Xie W; Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Schmitt AM; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Joharatnam-Hogan N; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Cornish GH; Retroviral Immunology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Pule M; Research Department of Haematology at University College London Cancer Institute, WC1E 6DD, London, UK.; Autolus Limited, The MediaWorks, 191 Wood Lane, London, W12 7F., Mekkaoui L; Autolus Limited, The MediaWorks, 191 Wood Lane, London, W12 7F., Ng KW; Retroviral Immunology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Carlyle E; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Edmonds K; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Del Rosario L; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Sarker S; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Lingard K; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Mangwende M; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Holt L; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Ahmod H; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Stone R; Autolus Limited, The MediaWorks, 191 Wood Lane, London, W12 7F., Gomes C; Autolus Limited, The MediaWorks, 191 Wood Lane, London, W12 7F., Flynn HR; Mass Spectrometry Proteomics Science Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK., Agua-Doce A; Flow Cytometry Scientific Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK., Hobson P; Flow Cytometry Scientific Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK., Caidan S; Safety, Health & Sustainability, The Francis Crick Institute, London, NW1 1AT, UK., Howell M; High Throughput Screening Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Wu M; High Throughput Screening Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Goldstone R; Advanced Sequencing Facility, The Francis Crick Institute, London, NW1 1AT, UK., Crawford M; Advanced Sequencing Facility, The Francis Crick Institute, London, NW1 1AT, UK., Cubitt L; Advanced Sequencing Facility, The Francis Crick Institute, London, NW1 1AT, UK., Patel H; Department of Bioinformatics and Biostatistics, The Francis Crick Institute, London, UK., Gavrielides M; Scientific Computing Scientific Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK., Nye E; Experimental Histopathology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Snijders AP; Mass Spectrometry Proteomics Science Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK., MacRae JI; Metabolomics Scientific Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK., Nicod J; Advanced Sequencing Facility, The Francis Crick Institute, London, NW1 1AT, UK., Gronthoud F; Department of Pathology, The Royal Marsden NHS Foundation Trust, London, NW1 1AT, UK., Shea RL; Department of Pathology, The Royal Marsden NHS Foundation Trust, London, NW1 1AT, UK.; Translational Cancer Biochemistry Laboratory, The Institute of Cancer Research, London, SW7 3RP, UK., Messiou C; Department of Radiology, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Cunningham D; Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey SM2 5PT., Chau I; Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey SM2 5PT., Starling N; Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey SM2 5PT., Turner N; Breast Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Welsh L; Neuro-oncology Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., van As N; Clinical Oncology Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Jones RL; Sarcoma Unit, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, SW3 6JJ, UK., Droney J; Palliative Medicine, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Banerjee S; Gynaecology Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Tatham KC; Anaesthetics, Perioperative Medicine and Pain Department, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Jhanji S; Anaesthetics, Perioperative Medicine and Pain Department, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., O'Brien M; Lung Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Curtis O; Lung Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Harrington K; Head and Neck, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.; Targeted Therapy Team, The Institute of Cancer Research, London, SW7 3RP, UK., Bhide S; Head and Neck, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Bazin J; Haemato-oncology Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Robinson A; Haemato-oncology Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Stephenson C; Haemato-oncology Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Slattery T; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Khan Y; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Tippu Z; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Leslie I; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Gennatas S; Acute Oncology Service, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.; Department of Medical Oncology, 14th Floor, Great Maze Pond Road, Tower Wing, Guy's Hospital, London SE1 9RY, UK., Okines A; Breast Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.; Acute Oncology Service, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Reid A; Uro-oncology unit, The Royal Marsden NHS Foundation Trust, Surrey, SM2 5PT., Young K; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Furness AJS; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Pickering L; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Gandhi S; Neurodegeneration Biology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG., Gamblin S; Structural Biology of Disease Processes Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; University College London Cancer Institute, London WC1E 6DD, UK., Nicholson E; Haemato-oncology Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Kumar S; Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey SM2 5PT., Yousaf N; Lung Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.; Acute Oncology Service, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Wilkinson KA; Tuberculosis Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; Wellcome Center for Infectious Disease Research in Africa, University Cape Town, Observatory 7925, Republic of South Africa., Swerdlow A; Division of Genetics and Epidemiology and Division of Breast Cancer Research, The Institute of Cancer Research, London, SW7 3RP, UK., Harvey R; Worldwide Influenza Centre, The Francis Crick Institute, London, NW1 1AT, UK., Kassiotis G; Retroviral Immunology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Larkin J; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Wilkinson RJ; Tuberculosis Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; Department of Infectious Disease, Imperial College London, W12 0NN, UK.; Wellcome Center for Infectious Disease Research in Africa, University Cape Town, Observatory 7925, Republic of South Africa., Turajlic S; Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.

Publikováno v: Research square [Res Sq] 2021 Sep 20. Date of Electronic Publication: 2021 Sep 20.