Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ryuzaburo, Yuki"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/da26dbdadb5246019aeb8fdec3397ae4
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Mitotic progression requires the precise formation of spindle microtubules based on mature centrosomes. During the G2/M transition, centrosome maturation progresses, and associated microtubules bundle to form mitotic spindle fibers and captu
Externí odkaz:
https://doaj.org/article/2422d73169d44b5090b4a1e015c1b108
Autor:
Ryuzaburo Yuki
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 141(11)
Epithelial-mesenchymal transition (EMT) is an important program in epithelial cancer cells to acquire the motility and invasion, which promotes cancer metastasis to remote organs. EMT is induced by various secreted factors, such as transforming growt
Autor:
Ayana Kakihana, Ryuzaburo Yuki, Hiroko Watanabe, Ryuji Yasutake, Namiko Okamoto, Hiroko Teshima, Yuki Ikeda, Yukiko Yonezu, Youhei Saito, Yuji Nakayama
Publikováno v:
Journal of cellular biochemistryREFERENCES. 122(12)
The mammalian HSP105/110 family consists of four members, including Hsp105 and Apg-1, which function as molecular chaperones. Recently, we reported that Hsp105 knockdown increases sensitivity to the DNA-damaging agent Adriamycin but decreases sensiti
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5706, p 5706 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences
Volume 22
Issue 11
Insulin-like growth factor 1 receptor (IGF1R), a receptor-type tyrosine kinase, transduces signals related to cell proliferation, survival, and differentiation. We recently reported that OSI-906, an IGF1R inhibitor, in combination with the Aurora B i
Autor:
Hitomi Hasegawa, Kenichi Ishibashi, Shoichi Kubota, Chihiro Yamaguchi, Ryuzaburo Yuki, Haruna Nakajo, Richard Eckner, Noritaka Yamaguchi, Kazunari K Yokoyama, Naoto Yamaguchi
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116048 (2014)
Activating transcription factor 2 (ATF2) and its homolog ATF7 are phosphorylated at Thr-69/Thr-71 and at Thr-51/Thr-53, respectively, by stress-activated MAPKs regulating their transcriptional functions in G1 and S phases. However, little is known ab
Externí odkaz:
https://doaj.org/article/3a30bdb1996440998e92adc2b0256b75
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(1)
When cells with excess DNA, such as tetraploid cells, undergo cell division, it can contribute to cellular transformation via asymmetrical chromosome segregation-generated genetic diversity. Cell cycle progression of tetraploid cells is suppressed by
Autor:
Katsuhito Fujiu, Ichiro Manabe, Junichi Sugita, Masaki Suimye Morioka, Fujimi Kudo, Yukiteru Nakayama, Yusuke Endo, Atsushi Kaneda, Toshinori Nakayama, Tsukasa Oshima, Issei Komuro, Yumiko Oishi, Ryozo Nagai, Ryuzaburo Yuki, Takayuki Isagawa, Takumi Matsubara, Jun Matsuda
Publikováno v:
Proc Natl Acad Sci U S A
Proper resolution of inflammation is vital for repair and restoration of homeostasis after tissue damage, and its dysregulation underlies various noncommunicable diseases, such as cardiovascular and metabolic diseases. Macrophages play diverse roles
Publikováno v:
Cancers, Vol 12, Iss 1054, p 1054 (2020)
Cancers
Volume 12
Issue 4
Cancers
Volume 12
Issue 4
Anaplastic lymphoma kinase (ALK), a receptor-type tyrosine kinase, is involved in the pathogenesis of several cancers. ALK has been targeted with small molecule inhibitors for the treatment of different cancers, but absolute success remains elusive.
Autor:
Hideyuki Ide, Josefina Piñón Hofbauer, Manami Harada, Tomomi Furihata, Xujia Zhou, Ryuzaburo Yuki, Kenjirou Higashi, Hanae Morio, Osamu Shimozato, Yuchen Sun, Naohiko Anzai, Hidetaka Akita, Kan Chiba, Christina Guttmann-Gruber, Naoto Yamaguchi
Publikováno v:
Biological and Pharmaceutical Bulletin. 41:445-449
Cancer-type organic anion transporting polypeptide 1B3 (Ct-OATP1B3) mRNA is a variant isoform of the liver-type OATP1B3. Because Ct-OATP1B3 mRNA shows an excellent cancer-specific expression profile in colorectal cancer (CRC), and that its expression