Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ryuto Komatsu"'
Autor:
Shuhei Hamano, Takuya Noguchi, Yukino Asai, Ryo Ito, Ryuto Komatsu, Tetsu Sato, Aya Inoue, Tomoe Maruyama, Tada-aki Kudo, Yusuke Hirata, Sawako Shindo, Yasuo Uchida, Gi-Wook Hwang, Atsushi Matsuzawa
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Overactivation of poly (ADP-ribose) polymerase-1 (PARP-1) triggers a noncanonical form of programmed cell death (PCD) called parthanatos, yet the mechanisms of its induction are not fully understood. We have recently demonstrated that the ag
Externí odkaz:
https://doaj.org/article/b7f5edef378747cea8f183b47365b8da
Autor:
Tatsuya Shimada, Yohsuke Yabuki, Takuya Noguchi, Mei Tsuchida, Ryuto Komatsu, Shuhei Hamano, Mayuka Yamada, Yusuke Ezaki, Yusuke Hirata, Atsushi Matsuzawa
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 10064 (2022)
Liver kinase B1 (LKB1) is a serine/threonine protein kinase that acts as a key tumor suppressor protein by activating its downstream kinases, such as AMP-activated protein kinase (AMPK). However, the regulatory actions of LKB1 and AMPK on DNA damage
Externí odkaz:
https://doaj.org/article/a3f3212c68684a388efabc831a2ccaf2
Autor:
Yuto Sekiguchi, Saya Takano, Takuya Noguchi, Tomohiro Kagi, Ryuto Komatsu, Maoko Tan, Yusuke Hirata, Atsushi Matsuzawa
Publikováno v:
The Journal of Immunology. 210:795-806
Gefitinib (GF), the tyrosine kinase inhibitor (TKI) targeting epidermal growth factor receptor, initiates lung inflammation through the NLR family pyrin domain containing 3 (NLRP3) inflammasome. However, the molecular targets and mechanisms underlyin