Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ryutaro Hirasawa"'
Autor:
Julien Richard Albert, Wan Kin Au Yeung, Keisuke Toriyama, Hisato Kobayashi, Ryutaro Hirasawa, Julie Brind’Amour, Aaron Bogutz, Hiroyuki Sasaki, Matthew Lorincz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The paternal genome in mice undergoes widespread DNA methylation loss post-fertilization. Here, the authors apply allele-specific analysis of WGBS data to show that a number of genomic regions are simultaneously de novo methylated on the paternal gen
Externí odkaz:
https://doaj.org/article/128797e6956e467bae7bb0618d815a9b
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76422 (2013)
The great majority of embryos generated by somatic cell nuclear transfer (SCNT) display defined abnormal phenotypes after implantation, such as an increased likelihood of death and abnormal placentation. To gain better insight into the underlying mec
Externí odkaz:
https://doaj.org/article/3f8722f9e32940aea4d1668e1f5a44f1
Publikováno v:
Translational and Regulatory Sciences. 4:61-67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c57619dbaf9cf2f6a63291cf1a619118
https://doi.org/10.33611/trs.2022-004
https://doi.org/10.33611/trs.2022-004
Autor:
Kanny K. Wan, Danielle Davis, Taylor N. Lee, Stephanie L. Ford-Scheimer, Antonio L. Andreu, Florence Bietrix, Justin Bryans, Marco T. Castro, Nobuyoshi Chiba, Jessica M. Faupel-Badger, Brittany Haynes, Ryutaro Hirasawa, Carlos M. Morel, Thiago Moreno L. Souza, David Morrow, Trent Munro, Stuart Newman, Anton E. Ussi, Poliana B. Zorzal, Matthew D. Hall, Donald C. Lo, Christine M. Cutillo
Publikováno v:
Nature Reviews Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87074b38b5e8f64a8caab0fcae942d91
https://doi.org/10.1038/d41573-022-00020-6
https://doi.org/10.1038/d41573-022-00020-6
Autor:
Julien Richard Albert, Hisato Kobayashi, Keisuke Toriyama, Wan Kin Au Yeung, Julie Brind’Amour, Matthew C. Lorincz, Hiroyuki Sasaki, Aaron B. Bogutz, Ryutaro Hirasawa
De novo DNA methylation (DNAme) during mammalian spermatogenesis yields a densely methylated genome, with the exception of CpG islands (CGIs), which are hypomethylated in sperm. Following fertilization, the paternal genome undergoes widespread DNAme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c8e8ca8a7696e5dfa62bcb9752ea6e
https://doi.org/10.1101/2020.03.26.009977
https://doi.org/10.1101/2020.03.26.009977
Autor:
Julia White, Petr Kocis, Florence Bietrix, Matthew D. Hall, Rosan Kreeftmeijer-Vegter, Nobuyoshi Chiba, Justin Bryans, Christopher P. Austin, Anton E. Ussi, Makoto Suematsu, Stuart Newman, Ryutaro Hirasawa, C. Taylor Gilliland, Barry Gee, Marian Hajduch
Publikováno v:
ACS Pharmacol Transl Sci
Translational science is defined as the field of investigation focused on understanding the scientific and operational principles underlying each step of the translational process. Further development of the field is advanced by describing the key de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4684ca79dc101cd5b254ce6e6ef1e5af
https://europepmc.org/articles/PMC7088880/
https://europepmc.org/articles/PMC7088880/
Autor:
Robert Feil, Ryutaro Hirasawa
Publikováno v:
Essays in Biochemistry
Essays in Biochemistry, Portland Press, 2010, 48 (1), pp.187--200. ⟨10.1042/bse0480187⟩
Essays in Biochemistry, Portland Press, 2010, 48 (1), pp.187--200. ⟨10.1042/bse0480187⟩
In many epigenetic phenomena, covalent modifications on DNA and chromatin mediate somatically heritable patterns of gene expression. Genomic imprinting is a classical example of epigenetic regulation in mammals. To date, more than 100 imprinted genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f73e6c333aaa86574cf67e4b4baaa8
https://doi.org/10.1042/bse0480187
https://doi.org/10.1042/bse0480187
Autor:
Hiroyuki Sasaki, Shoji Tajima, Rudolf Jaenisch, En Li, Hatsune Chiba, Masahiro Kaneda, Ryutaro Hirasawa
Publikováno v:
Genes & Development. 22:1607-1616
Parental origin-specific DNA methylation regulates the monoallelic expression of the mammalian imprinted genes. The methylation marks or imprints are established in the parental germline and maintained throughout embryonic development. However, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70ac31accec36bc8c0680cd943d804cc
https://doi.org/10.1101/gad.1667008
https://doi.org/10.1101/gad.1667008
Autor:
Narumi Ogonuki, Mami Oikawa, Ryutaro Hirasawa, Hiroaki Nagatomo, Shogo Matoba, Kuniya Abe, Kimiko Inoue, Eiji Mizutani, Atsuo Ogura, Atsu Aiba, Satoshi Kamimura, Hirosuke Shiura, Hidetoshi Kassai, Teruhiko Wakayama
Publikováno v:
Biology of Reproduction. 92
Whereas cloning mammals by direct somatic cell nuclear transfer has been successful using a wide range of donor cell types, neurons from adult brain remain ‘‘unclonable’’ for unknown reasons. Here, using a combination of two epigenetic approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b11d25ebc4127be920aaae0a932a6f25
https://doi.org/10.1095/biolreprod.114.123455
https://doi.org/10.1095/biolreprod.114.123455
Autor:
Eiji, Mizutani, Mami, Oikawa, Hidetoshi, Kassai, Kimiko, Inoue, Hirosuke, Shiura, Ryutaro, Hirasawa, Satoshi, Kamimura, Shogo, Matoba, Narumi, Ogonuki, Hiroaki, Nagatomo, Kuniya, Abe, Teruhiko, Wakayama, Atsu, Aiba, Atsuo, Ogura
Publikováno v:
Biology of reproduction. 92(3)
Whereas cloning mammals by direct somatic cell nuclear transfer has been successful using a wide range of donor cell types, neurons from adult brain remain "unclonable" for unknown reasons. Here, using a combination of two epigenetic approaches, we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3763484461d9edde9837c89318efc71
https://pubmed.ncbi.nlm.nih.gov/25653280
https://pubmed.ncbi.nlm.nih.gov/25653280