Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Ryusuke Yoshimi"'
Autor:
Kunihiro Ichinose, Shuntaro Sato, Takashi Igawa, Momoko Okamoto, Ayuko Takatani, Yushiro Endo, Sosuke Tsuji, Toshimasa Shimizu, Remi Sumiyoshi, Tomohiro Koga, Shin-ya Kawashiri, Naoki Iwamoto, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Nobuyuki Yajima, Ken-Ei Sada, Yoshia Miyawaki, Ryusuke Yoshimi, Yasuhiro Shimojima, Shigeru Ohno, Hiroshi Kajiyama, Shuzo Sato, Michio Fujiwara, Atsushi Kawakami
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-7 (2024)
Abstract Background Previous studies have shown conflicting evidence regarding the incidence of cancer in patients with systemic lupus erythematosus (SLE) compared with that in healthy individuals. Calcineurin inhibitors (CNIs) such as cyclosporine a
Externí odkaz:
https://doaj.org/article/8b489b60467f48bba3b92f09524e6ec3
Autor:
Lisa Hirahara, Yohei Kirino, Yutaro Soejima, Yuki Iizuka, Ryusuke Yoshimi, Yuichiro Fujieda, Tatsuya Atsumi, Toshihiro Tono, Daisuke Kobayashi, Akira Meguro, Masaki Takeuchi, Kentaro Sakamaki, Mitsuhiro Takeno, Nobuhisa Mizuki, Hideaki Nakajima
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundLittle is known about the relationship between the disease activity of Behçet disease (BD) and the incidence of inflammatory major organ events.ObjectivesIn this prospective registry study, we investigated the association between the Behç
Externí odkaz:
https://doaj.org/article/9a7d9d367d9d48429979cef6e6126f97
Autor:
Soichiro Adachi, Kaoru Takase-Minegishi, Ayaka Maeda, Hideto Nagai, Nobuyuki Horita, Ryusuke Yoshimi, Yohei Kirino, Hideaki Nakajima
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 6, Pp 1623-1636 (2023)
Abstract Introduction Patients with adult-onset Still’s disease (AOSD) are at risk of developing macrophage activation syndrome (MAS), a life-threatening condition. Some cases of MAS have been reported following the use of biological agents, highli
Externí odkaz:
https://doaj.org/article/4232205e722741fb85a748dc288f84b8
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2024)
To date, research on the role of the brainstem and spinal cord in motor behavior has relied on in vitro preparations of the neonatal rodent spinal cord, with or without the brainstem; their spatial and temporal scope are subject to technical limitati
Externí odkaz:
https://doaj.org/article/f40e61d7d2fb4cb786c5e73500f024ba
Autor:
Chiharu Hidekawa, Ryusuke Yoshimi, Yusuke Saigusa, Jun Tamura, Noriko Kojitani, Naoki Suzuki, Natsuki Sakurai, Yuji Yoshioka, Yumiko Sugiyama-Kawahara, Yosuke Kunishita, Daiga Kishimoto, Kana Higashitani, Yuichiro Sato, Takaaki Komiya, Hideto Nagai, Naoki Hamada, Ayaka Maeda, Naomi Tsuchida, Lisa Hirahara, Yutaro Soejima, Kaoru Takase-Minegishi, Yohei Kirino, Nobuyuki Yajima, Ken-ei Sada, Yoshia Miyawaki, Kunihiro Ichinose, Shigeru Ohno, Hiroshi Kajiyama, Shuzo Sato, Yasuhiro Shimojima, Michio Fujiwara, Hideaki Nakajima
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectivesInfection is a leading cause of death in patients with systemic lupus erythematosus (SLE). Alt hough hydroxychloroquine (HCQ) has been reported to inhibit infection, evidence from Asian populations remains insufficient. We investigated this
Externí odkaz:
https://doaj.org/article/250d87a98654495f8ee627fe93606299
Autor:
Ryo Yanai, Nobuyuki Yajima, Nao Oguro, Yasuhiro Shimojima, Shigeru Ohno, Hiroshi Kajiyama, Kunihiro Ichinose, Shuzo Sato, Michio Fujiwara, Yoshia Miyawaki, Ryusuke Yoshimi, Takashi Kida, Yusuke Matsuo, Keisuke Nishimura, Ken-ei Sada
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 2, Pp 421-431 (2023)
Abstract Introduction Patients with systemic lupus erythematosus (SLE) frequently change attending physicians. The number of changes in attending physicians is related to the accumulated organ damage in patients with diabetes mellitus and inflammator
Externí odkaz:
https://doaj.org/article/25a8d48089224c4788673035a327e06b
Autor:
Kazuya Abe, Yuichi Ishikawa, Yasuhiko Kita, Nobuyuki Yajima, Eisuke Inoue, Ken-ei Sada, Yoshia Miyawaki, Ryusuke Yoshimi, Yasuhiro Shimojima, Shigeru Ohno, Hiroshi Kajiyama, Kunihiro Ichinose, Shuzo Sato, Michio Fujiwara
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-8 (2022)
Abstract Background Infection is a major cause of mortality in patients with systemic lupus erythematosus (SLE). Therefore, minimizing the risk of infection is an important clinical goal to improve the long-term prognosis of SLE patients. Treatment w
Externí odkaz:
https://doaj.org/article/a413829d17284e5eaacf496f69dabfd4
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Pyrin/TRIM20 is expressed in the neutrophils and monocytes/macrophages and regulates caspase-1 activation and interleukin-1β maturation. Although the mutations in the PRY/SPRY domain of pyrin cause familial Mediterranean fever (FMF), the me
Externí odkaz:
https://doaj.org/article/1d4515f104f746ccbe0cd2c12f38b9f3
Autor:
Tatsuma Ban, Masako Kikuchi, Go R. Sato, Akio Manabe, Noriko Tagata, Kayo Harita, Akira Nishiyama, Kenichi Nishimura, Ryusuke Yoshimi, Yohei Kirino, Hideyuki Yanai, Yoshiko Matsumoto, Shuichi Suzuki, Hiroe Hihara, Masashi Ito, Kappei Tsukahara, Kentaro Yoshimatsu, Tadashi Yamamoto, Tadatsugu Taniguchi, Hideaki Nakajima, Shuichi Ito, Tomohiko Tamura
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
IRF5 is a potential target for therapy in systemic lupus erythematosus (SLE). Here the authors show using mouse SLE-like models that genetic or chemical inhibition of IRF5 after SLE onset could be more effective than, or an add on for, currently util
Externí odkaz:
https://doaj.org/article/bdb59bea8b1b42119ff3a063d9c303ba
Autor:
Yosuke Kunishita, Yohei Kirino, Naomi Tsuchida, Ayaka Maeda, Yuichiro Sato, Kaoru Takase-Minegishi, Ryusuke Yoshimi, Hideaki Nakajima
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is an autoinflammatory disease caused by somatic variants in the UBA1 gene that lead to severe systemic inflammation and myelodysplastic syndrome. Although no standard therapy
Externí odkaz:
https://doaj.org/article/8518ad7e62de43fa81660bcedd3a5d1d