Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ryusuke Sugita"'
Autor:
Ryusuke Sugita, Kazufumi Kubota, Kotaro Sugimoto, Yuki Tachida, Takahiro Shibayama, Toshihiro Kiho, Katsuhiro Kawakami, Kohei Shimada
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 2, Pp 128-135 (2016)
Prostaglandin E2 (PGE2), one of the terminal products in the cyclooxygenase pathway, plays an important role in various inflammatory responses. To determine whether selective inhibition of PGE2 may relieve these inflammatory symptoms, we synthesized
Externí odkaz:
https://doaj.org/article/66760a26bd41481d9015cce95e132d7e
Autor:
Ryusuke Sugita, Harumi Kuwabara, Kazufumi Kubota, Kotaro Sugimoto, Toshihiro Kiho, Atsushi Tengeiji, Katsuhiro Kawakami, Kohei Shimada
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Prostaglandin E2 (PGE2) is well known as a mediator of inflammatory symptoms such as fever, arthritis, and inflammatory pain. In the present study, we evaluated the analgesic effect of our selective PGE2 synthesis inhibitor, compound I, 2-methyl-2-[c
Externí odkaz:
https://doaj.org/article/675a55b2ab26412da50e75fde9b2f721
Autor:
Toshihiro Kiho, Kotaro Sugimoto, Atsushi Tengeiji, Yuichiro Imamura, Ryusuke Sugita, Harumi Kuwabara, Kohei Shimada, Kazufumi Kubota, Katsuhiro Kawakami
Publikováno v:
Inflammation. 39:907-915
Prostaglandin E2 (PGE2) is a terminal prostaglandin in the cyclooxygenase (COX) pathway. Inhibition of PGE2 production may relieve inflammatory symptoms such as fever, arthritis, and inflammatory pain. We report here the profile of a novel selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be038f81f6626b17461972ee1f43fa3
https://doi.org/10.1007/s10753-016-0323-5
https://doi.org/10.1007/s10753-016-0323-5
Autor:
Katsuhiro Kawakami, Toshihiro Kiho, Kotaro Sugimoto, Kazufumi Kubota, Takahiro Shibayama, Ryusuke Sugita, Kohei Shimada, Yuki Tachida
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 2, Pp 128-135 (2016)
Prostaglandin E2 (PGE2), one of the terminal products in the cyclooxygenase pathway, plays an important role in various inflammatory responses. To determine whether selective inhibition of PGE2 may relieve these inflammatory symptoms, we synthesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f688c7fbe9b4e3086ca77fe35ddedf4
https://doi.org/10.1016/j.jphs.2016.01.009
https://doi.org/10.1016/j.jphs.2016.01.009
Autor:
Kazufumi Kubota, Harumi Kuwabara, Kotaro Sugimoto, Katsuhiro Kawakami, Toshihiro Kiho, Kohei Shimada, Atsushi Tengeiji, Ryusuke Sugita
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Mediators of Inflammation
Mediators of Inflammation
Prostaglandin E2(PGE2) is well known as a mediator of inflammatory symptoms such as fever, arthritis, and inflammatory pain. In the present study, we evaluated the analgesic effect of our selective PGE2synthesis inhibitor, compound I, 2-methyl-2-[cis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9886603c01eef2de7a3109973d3cdcc
https://doaj.org/article/675a55b2ab26412da50e75fde9b2f721
https://doaj.org/article/675a55b2ab26412da50e75fde9b2f721
Autor:
Chisato Umeda, Erina Hata, Naoki Takemura, Ryusuke Sugita, Kei Sonoyama, Ryoko Andoh, Atsuko Miki
Publikováno v:
Bioscience of Microbiota, Food and Health. 31:77-84
We previously observed that gut colonization by Candida albicans promoted serum antibody response to orally administered ovalbumin in mice. We therefore postulated that C. albicans affects oral tolerance induction. The present study tested this idea.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::026f6b91ebce6525deb214f8d88e544a
https://doi.org/10.12938/bmfh.31.77
https://doi.org/10.12938/bmfh.31.77
Autor:
Tomihisa Yokoyama, Hiroko Kimoto, Daigo Asano, Ryusuke Sugita, Kazufumi Kubota, Ryuta Koishi, Takeshi Kuroda, Yuki Domon, Akiko Shimizugawa, Sayaka Suzuki, Kazuhiko Tamaki, Yutaka Kitano, Tsuyoshi Shinozuka, Hiroyuki Kobayashi
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(22)
A novel class of NaV1.7 inhibitors has been identified by high-throughput screening followed by structure activity relationship studies. Among this series of compounds, piperidine 9o showed potent human and mouse NaV1.7 inhibitory activities with fai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40169ed87884e3ea4df0259263600814
https://pubmed.ncbi.nlm.nih.gov/26358159
https://pubmed.ncbi.nlm.nih.gov/26358159
Autor:
Jun Watanabe, Kei Sonoyama, Atsuko Miki, Natsu Yamaguchi, Naoki Takemura, Ryusuke Sugita, Jun Kawabata
Publikováno v:
Gut. 55:954-960
Backgrounds and aims: Controversy still exists as to whether gastrointestinal colonisation by Candida albicans contributes to aggravation of atopic dermatitis. We hypothesised that Candida colonisation promotes food allergy, which is known to contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea359b63d4593889adac329e53a01c7
https://doi.org/10.1136/gut.2005.084954
https://doi.org/10.1136/gut.2005.084954
Publikováno v:
北海道医療大学看護福祉学部紀要. 13:59-63
本研究の目的は、高齢者に対する教育的な介入プログラムである「物忘れ予防教室」を、地域介護支援センター職員がそのマニュアルに沿って展開し、高齢者の記憶や自己効力感に対す
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::f6d49d9b1b885879b33593b065b51dd7
http://id.nii.ac.jp/1145/00006726/
http://id.nii.ac.jp/1145/00006726/
Publikováno v:
Medical mycology. 49(3)
We examined whether Candida albicans gut colonization aggravates immune diseases in mice. Chronic and latent C. albicans gut colonization was established by the intragastric inoculation of C. albicans in mice fed as part of a purified diet. Allergic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd71ffe6deb0879362a5bef1d6c7126
https://pubmed.ncbi.nlm.nih.gov/20807027
https://pubmed.ncbi.nlm.nih.gov/20807027