Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ryusuke Sakamoto"'
Autor:
Ying Zhang, Yoshiyasu Fukusumi, Mutsumi Kayaba, Takashi Nakamura, Ryusuke Sakamoto, Naoki Ashizawa, Hiroshi Kawachi
Publikováno v:
Nefrología, Vol 41, Iss 5, Pp 539-547 (2021)
Background: Topiroxostat, an inhibitor of xanthine oxidoreductase (XOR) was shown to reduce urinary albumin excretion of hyperuricemic patients with chronic kidney disease. However, its pharmacological mechanism is not well understood. In this study,
Externí odkaz:
https://doaj.org/article/52deaa41b5124369b4ede2646ddd0ee5
Autor:
Noriaki Nagai, Ryusuke Sakamoto, Seiji Yamamoto, Saori Deguchi, Hiroko Otake, Tadatoshi Tanino
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 4990 (2019)
Indomethacin (IMC)-induced gastrointestinal (GI) injuries are more common in rheumatoid arthritis (RA) patients than in other IMC users, and the overexpression of nitric oxide (NO) via inducible NO synthase (iNOS) is related to the seriousness of IMC
Externí odkaz:
https://doaj.org/article/7745f8d73ed54c379e182dcf07f83546
Autor:
Hiroshi Kawachi, Ryusuke Sakamoto, Ying Zhang, Yoshiyasu Fukusumi, Mutsumi Kayaba, Naoki Ashizawa, Takashi Nakamura
Publikováno v:
Nefrología, Vol 41, Iss 5, Pp 539-547 (2021)
Nefrología (English Edition), Vol 41, Iss 5, Pp 539-547 (2021)
Nefrología (English Edition), Vol 41, Iss 5, Pp 539-547 (2021)
Background: Topiroxostat, an inhibitor of xanthine oxidoreductase (XOR) was shown to reduce urinary albumin excretion of hyperuricemic patients with chronic kidney disease. However, its pharmacological mechanism is not well understood. In this study,
Publikováno v:
Ichthyological Research. 68:548-551
Examination of the dorsal spinule patch in Lagocephalus spadiceus specimens revealed the existence of two intraspecific forms, the “wheeleri”-form, characterized by an elliptical patch, and the “spadiceus”-form, with a rhomboidal patch with a
Publikováno v:
Clinical Drug Investigation
Background and Objectives Topiroxostat—a novel selective xanthine oxidoreductase inhibitor—has been reported to reduce serum urate levels. The purpose of this study was to assess the efficacy and safety of long-term topiroxostat administration in
Autor:
Tomomitsu Sasaki, Ryusuke Sakamoto, Daisuke Okui, Tatsuo Hosoya, Kazutaka Narita, Kenjiro Kimura, Takashi Wada, Daisuke Honda
Publikováno v:
Clinical and Experimental Nephrology. 22(4):860-870
金沢大学医薬保健研究域医学系
Background: Hyperuricemia is supposed to be an independent risk factor for kidney dysfunction in diabetic patients. We attempted to examine the uric acid-lowering effect and the renoprotective effect of
Background: Hyperuricemia is supposed to be an independent risk factor for kidney dysfunction in diabetic patients. We attempted to examine the uric acid-lowering effect and the renoprotective effect of
Autor:
Takayo Murase, Nobutaka Morimoto, Mai Nampei, Takashi Iwanaga, Takashi Nakamura, Naoki Ashizawa, Ryusuke Sakamoto
Publikováno v:
European Journal of Pharmacology. 780:224-231
Topiroxostat, a xanthine oxidoreductase (XOR) inhibitor, has been shown to decrease the urinary albumin-to-creatinine ratio compared with placebo in hyperuricemic patients with stage 3 chronic kidney disease. Thus, we aimed to ascertain the albuminur
Publikováno v:
Journal of the Japan Society of Applied Electromagnetics and Mechanics. 21:222-227
Publikováno v:
Biotechnology Progress. 20:1128-1133
Misfolding poses a serious problem in the biotechnological field in obtaining the active protein from inclusion bodies. Here we show that high temperature increases the refolding yield of reduced lyosyzme by a simple dilution method. The refolding yi
Autor:
Keiichiro Yoshida, Ryusuke Sakamoto
Publikováno v:
The Proceedings of the Symposium on Environmental Engineering. :199-200