Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Ryunosuke, Ohkawa"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Cholesterol efflux capacity (CEC), commonly measured as a useful risk marker of atherosclerotic cardiovascular disease, depends on high-density lipoprotein (HDL) functionality and its concentration. We defined the relative HDL functionality
Externí odkaz:
https://doaj.org/article/21d342b88a7b4e6fa9af242f73aa58f7
Autor:
Azusa Yamazaki, Yoko Nukui, Takahiro Kameda, Ryoichi Saito, Yuki Koda, Naoya Ichimura, Shuji Tohda, Ryunosuke Ohkawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Coronavirus disease (COVID-19) has caused extensive mortality globally; therefore, biomarkers predicting the severity and prognosis of COVID-19 are essential. This study aimed to evaluate the application of presepsin (P-SEP) and thrombomodul
Externí odkaz:
https://doaj.org/article/895f675d0d28439dba32a3558cc6cea9
Autor:
Ryunosuke Ohkawa, Hann Low, Nigora Mukhamedova, Ying Fu, Shao-Jui Lai, Mai Sasaoka, Ayuko Hara, Azusa Yamazaki, Takahiro Kameda, Yuna Horiuchi, Peter J. Meikle, Gerard Pernes, Graeme Lancaster, Michael Ditiatkovski, Paul Nestel, Boris Vaisman, Denis Sviridov, Andrew Murphy, Alan T. Remaley, Dmitri Sviridov, Minoru Tozuka
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1577-1588 (2020)
Lipoproteins play a key role in transport of cholesterol to and from tissues. Recent studies have also demonstrated that red blood cells (RBCs), which carry large quantities of free cholesterol in their membrane, play an important role in reverse cho
Externí odkaz:
https://doaj.org/article/c85e2bd927424090baf6850db15b6a1c
Autor:
Ryunosuke Ohkawa, Makoto Kurano, Noboru Sakai, Tatsuya Kishimoto, Takahiro Nojiri, Koji Igarashi, Shigemi Hosogaya, Yukio Ozaki, Tomotaka Dohi, Katsumi Miyauchi, Hiroyuki Daida, Junken Aoki, Shigeo Okubo, Hitoshi Ikeda, Minoru Tozuka, Yutaka Yatomi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Blood choline has been proposed as a predictor of acute coronary syndrome (ACS), however different testing procedures might affect the choline concentration because the lysophospholipase D activity of autotaxin (ATX) can convert lysophosphat
Externí odkaz:
https://doaj.org/article/54d0aae38fab4404ba5e3ce2c9e90834
Autor:
Makoto Kurano, Kuniyuki Kano, Tomotaka Dohi, Hirotaka Matsumoto, Koji Igarashi, Masako Nishikawa, Ryunosuke Ohkawa, Hitoshi Ikeda, Katsumi Miyauchi, Hiroyuki Daida, Junken Aoki, Yutaka Yatomi
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 2, Pp 433-442 (2017)
Lysophosphatidic acids (LysoPAs) and lysophosphatidylserine (LysoPS) are emerging lipid mediators proposed to be involved in the pathogenesis of acute coronary syndrome (ACS). In this study, we attempted to elucidate how LysoPA and LysoPS become elev
Externí odkaz:
https://doaj.org/article/01cdbcb81252448da73579c87eec4b46
Autor:
Nigora Mukhamedova, Anh Hoang, Dragana Dragoljevic, Larisa Dubrovsky, Tatiana Pushkarsky, Hann Low, Michael Ditiatkovski, Ying Fu, Ryunosuke Ohkawa, Peter J Meikle, Anelia Horvath, Beda Brichacek, Yury I Miller, Andrew Murphy, Michael Bukrinsky, Dmitri Sviridov
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007907 (2019)
HIV infection has a profound effect on "bystander" cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors. Here we show that exosomes containing HIV-1 protein Nef (exNef) a
Externí odkaz:
https://doaj.org/article/e9e4d551c4234d93af6f7c00d4033bd0
Background Paraoxonase 1 (PON1) enzyme is closely associated with the antioxidant, anti-inflammatory, and antiatherosclerotic functions of HDL. Although many clinical studies have evaluated the relationship between PON1 activity and various diseases,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::878260471a868a7c0c6011decf2b2bc4
https://doi.org/10.21203/rs.3.rs-2763963/v1
https://doi.org/10.21203/rs.3.rs-2763963/v1
Autor:
Yume Mutsuda, Tsunehiro Miyakoshi, Yuna Horiuchi, Takahiro Kameda, Minoru Tozuka, Ryunosuke Ohkawa
Publikováno v:
Bioscience Reports. 43
During the past decade, evaluation of high-density lipoprotein (HDL) functionality has been well studied for predicting cardiovascular disease (CVD) risk. Cholesterol efflux capacity (CEC) is the strongest candidate as the biomarker out of various HD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7619843cc03299f4a83839e2f9e32244
https://doi.org/10.1042/bsr20221519
https://doi.org/10.1042/bsr20221519
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 59:134-143
Objectives Cholesterol efflux capacity (CEC), an atheroprotective function of high-density lipoprotein, is expected to be a potential biomarker for cardiovascular disease. However, CEC has not been widely introduced for application in clinical labora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09bdc47ceafbdd55a7abf80f0732986
https://doi.org/10.1177/00045632211054406
https://doi.org/10.1177/00045632211054406
Autor:
Shao-Jui Lai, Kouji Yano, Ryunosuke Ohkawa, Takahiro Kameda, Shitsuko Shimano, Naoya Ichimura, Minoru Tozuka, Shuji Tohda, Y. Horiuchi, Yuriko Kurihara
Publikováno v:
Biological Chemistry. 403:265-277
Endothelial cell (EC) migration is essential for healing vascular injuries. Previous studies suggest that high-density lipoprotein (HDL) and apolipoprotein A-I (apoA-I), the major protein constituent of HDL, have endothelial healing functions. In car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f94de6448ff0630884af81d98fc70bf
https://doi.org/10.1515/hsz-2021-0247
https://doi.org/10.1515/hsz-2021-0247