Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Ryuji IKEDA"'
Autor:
Tomohiro Ueda, Kousuke Yamshita, Retsu Kawazoe, Yuta Sayawaki, Yoshiki Morisawa, Ryosuke Kamezaki, Ryuji Ikeda, Shinya Shiraishi, Yoshikazu Uchiyama, Shigeki Ito
Publikováno v:
Asia Oceania Journal of Nuclear Medicine and Biology, Vol 12, Iss 2, Pp 108-119 (2024)
Objective(s): To develop the following three attenuation correction (AC) methods for brain 18F-fluorodeoxyglucose-positron emission tomography (PET), using deep learning, and to ascertain their precision levels: (i) indirect method; (ii) direct metho
Externí odkaz:
https://doaj.org/article/d40aa16e1e6e41bd995a1dbb9f8c0d48
Autor:
Taeko Tomimatsu, Kousuke Yamshita, Takumi Sakata, Ryosuke Kamezaki, Ryuji Ikeda, Shinya Shiraishi, Yoshikazu Uchiyama, Shigeki Ito
Publikováno v:
Asia Oceania Journal of Nuclear Medicine and Biology, Vol 12, Iss 2, Pp 120-130 (2024)
Objective(s): A simple noninvasive microsphere (SIMS) method using 123I-IMP and an improved brain uptake ratio (IBUR) method using 99mTc-ECD for the quantitative measurement of regional cerebral blood flow have been recently reported. The input funct
Externí odkaz:
https://doaj.org/article/72339c49601f4390a62f22ed214192ff
Autor:
Yusei Yamada, Madoka Fukaura‐Nishizawa, Asami Nishiyama, Akira Ishii, Tatsuya Kawata, Aina Shirakawa, Mayuko Tanaka, Yuki Kondo, Toru Takeo, Naomi Nakagata, Toru Miwa, Hiroki Takeda, Yorihisa Orita, Keiichi Motoyama, Taishi Higashi, Hidetoshi Arima, Takahiro Seki, Yuki Kurauchi, Hiroshi Katsuki, Katsumi Higaki, Kentaro Minami, Naoki Yoshikawa, Ryuji Ikeda, Muneaki Matsuo, Tetsumi Irie, Yoichi Ishitsuka
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 8, Pp n/a-n/a (2023)
Abstract Background Niemann–Pick disease type C (NPC) is a fatal neurodegenerative disorder caused by abnormal intracellular cholesterol trafficking. Cyclodextrins (CDs), the most promising therapeutic candidates for NPC, but with concerns about ot
Externí odkaz:
https://doaj.org/article/4e90738b28c44e4c9ddaf53a1c5805b3
Publikováno v:
PCN Reports, Vol 2, Iss 1, Pp n/a-n/a (2023)
Abstract Aim Yokukansan is a Japanese herbal medicine used in psychiatry to treat behavioral and psychological symptoms of dementia and other psychiatric symptoms. However, the glycyrrhizic acid included in this medicine can cause pseudoaldosteronism
Externí odkaz:
https://doaj.org/article/b696d5963bf0406cb25620102caaa103
Autor:
Toshihiro Tsuruda, Yuichiro Sato, Masaki Tomita, Hiroyuki Tanaka, Kinta Hatakeyama, Misa Otsu, Aya Kawano, Keiko Nagatomo, Naoki Yoshikawa, Ryuji Ikeda, Yujiro Asada, Koichi Kaikita
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundCardiac troponin-T (TNNT2) is exclusively present in cardiac muscle. Measurement of TNNT2 is used for diagnosing acute coronary syndrome. However, its expression may not be limited in myocardium. This study aimed at evaluating the expressio
Externí odkaz:
https://doaj.org/article/25724b3962fb498499eaea01f3bd4685
Autor:
Sho Tabata, Masatatsu Yamamoto, Hisatsugu Goto, Akiyoshi Hirayama, Maki Ohishi, Takuya Kuramoto, Atsushi Mitsuhashi, Ryuji Ikeda, Misako Haraguchi, Kohichi Kawahara, Yoshinari Shinsato, Kentaro Minami, Atsuro Saijo, Yuko Toyoda, Masaki Hanibuchi, Yasuhiko Nishioka, Saburo Sone, Hiroyasu Esumi, Masaru Tomita, Tomoyoshi Soga, Tatsuhiko Furukawa, Shin-ichi Akiyama
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract Thymidine phosphorylase (TP) is a rate-limiting enzyme in the thymidine catabolic pathway. TP is identical to platelet-derived endothelial cell growth factor and contributes to tumour angiogenesis. TP induces the generation of reactive oxyge
Externí odkaz:
https://doaj.org/article/032a6e04b06a4f58b3f4b74ff4b3e639
Autor:
Sho Tabata, Masatatsu Yamamoto, Hisatsugu Goto, Akiyoshi Hirayama, Maki Ohishi, Takuya Kuramoto, Atsushi Mitsuhashi, Ryuji Ikeda, Misako Haraguchi, Kohichi Kawahara, Yoshinari Shinsato, Kentaro Minami, Atsuro Saijo, Masaki Hanibuchi, Yasuhiko Nishioka, Saburo Sone, Hiroyasu Esumi, Masaru Tomita, Tomoyoshi Soga, Tatsuhiko Furukawa, Shin-ichi Akiyama
Publikováno v:
Cell Reports, Vol 19, Iss 7, Pp 1313-1321 (2017)
Thymidine phosphorylase (TP), a rate-limiting enzyme in thymidine catabolism, plays a pivotal role in tumor progression; however, the mechanisms underlying this role are not fully understood. Here, we found that TP-mediated thymidine catabolism could
Externí odkaz:
https://doaj.org/article/8226b180e12e490b9a291bd6e5e1a1d6
Autor:
Naoki Yoshikawa, Hidemi Takeshima, Masaaki Sekine, Keiichi Akizuki, Tomonori Hidaka, Kazuya Shimoda, Ryuji Ikeda
Publikováno v:
Pharmaceuticals, Vol 14, Iss 4, p 353 (2021)
A polymorphism in the gene encoding the metabolic enzyme cytochrome P450 family 3 subfamily A member 5 (CYP3A5) is a particularly influential factor in the use of tacrolimus in Japanese patients. Those who are homozygotic for the *3 mutation lack CYP
Externí odkaz:
https://doaj.org/article/4b9c0b28b4d740e2a00457c7f43a5a23
Autor:
Kentaro Minami, Yoshinari Shinsato, Masatatsu Yamamoto, Homare Takahashi, Shaoxuan Zhang, Yukihiko Nishizawa, Sho Tabata, Ryuji Ikeda, Kohich Kawahara, Kazutake Tsujikawa, Kazuo Chijiiwa, Katsushi Yamada, Shin-ichi Akiyama, Sandra Pérez-Torras, Marcal Pastor-Anglada, Tatsuhiko Furukawa, Takeda Yasuo
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 3, Pp 319-325 (2015)
Gemcitabine is widely used for pancreatic, lung, and bladder cancer. However, drug resistance against gemcitabine is a large obstacle to effective chemotherapy. Nucleoside transporters, nucleoside and nucleotide metabolic enzymes, and efflux transpor
Externí odkaz:
https://doaj.org/article/e28f81e30aca46799f20a3a01b38934e
Publikováno v:
Journal of Pharmacological Sciences, Vol 100, Iss 3, Pp 205-210 (2006)
Abstract.: To understand the molecular pathogenesis of ossification of the posterior longitudinal ligament of the spine (OPLL), an ectopic bone formation disease, we performed cDNA microarray analysis on cultured ligament cells from OPLL patients to
Externí odkaz:
https://doaj.org/article/9e613102e9c848eb8f9d967e0cd0e2e3