Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Ryuji Hata"'
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 54-68 (2021)
Various mitochondrial diseases, including mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), are associated with heteroplasmic mutations in mitochondrial DNA (mtDNA). Herein, we refined a previously generated G13513A mtD
Externí odkaz:
https://doaj.org/article/852fa12218ac4383bfbde62069b06a17
Autor:
Ryuji Hata
Publikováno v:
Journal of Stem Cells and Regenerative Medicine, Vol 5, Iss 2, Pp 58-58 (2009)
The prevalence of acquired hearing loss is very high. About 10% of the total population and more than one third of the population over 65 years suffer from debilitating hearing loss. The most common type of hearing loss in adults is idiopathic sudden
Externí odkaz:
https://doaj.org/article/2d1e7051ccb4449eb241deb974129088
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 54-68 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Various mitochondrial diseases, including mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), are associated with heteroplasmic mutations in mitochondrial DNA (mtDNA). Herein, we refined a previously generated G13513A mtD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01b6ee24313098fc704a91fca72d008
http://www.sciencedirect.com/science/article/pii/S2329050120302217
http://www.sciencedirect.com/science/article/pii/S2329050120302217
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
Induced pluripotent stem cells (iPSCs) are suitable for studying mitochondrial diseases caused by mitochondrial DNA (mtDNA) mutations. Here, we generated iPSCs from a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e71e122f0435d80394163e7819ed9f2
http://link.springer.com/article/10.1038/s41598-017-15871-y
http://link.springer.com/article/10.1038/s41598-017-15871-y
Autor:
Ryuji Hata, Makoto Kuroda, Shigeru Nakai, Yoshiyuki Hiki, Masao Kato, Nobuya Kitaguchi, Midori Hasegawa, Masato Abe, Kazuyoshi Sakai, Kazunori Kawaguchi, Yukio Yuzawa, Takao Senda
Publikováno v:
Journal of Alzheimer's Disease. 51:997-1002
As a proof of concept that removal of blood amyloid-β (Aβ) can reduce Aβ deposition in the brains of patients with Alzheimer's disease, cortices of patients who had undergone hemodialysis (HD), which removes Aβ from the blood, were histochemicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11076f9d053a033dc6c368fdd4f024dd
https://doi.org/10.3233/jad-151139
https://doi.org/10.3233/jad-151139
Autor:
Dai Watanabe, Haruhisa Inoue, Tatsushi Toda, Takayuki Kondo, Satoko Yamawaki, Tatsutoshi Nakahata, Shu-ichi Ueno, Kei Maruyama, Hiroyuki Hioki, Motoko Naitoh, Tsuneyoshi Seki, Takeshi Kaneko, Yutaka Ohsawa, Shinya Yamanaka, Isao Asaka, Takashi Asada, William L. Klein, Kayoko Tsukita, Naoki Yahata, Osamu Hori, Keiko Imamura, Keisuke Okita, Akira Watanabe, Masashi Asai, Kazuhiro Kobayashi, Katsuhiro Yoshikawa, Ryuji Hata, Kazuma Murakami, Shigehiko Suzuki, Yumiko Kutoku, Rie Nakano, Kazuhiro Irie, Kazutoshi Takahashi, Ryosuke Takahashi, Tominari Choshi, Kaori Watanabe, Hiroshi Mori, Naohiro Egawa, Yoshihide Sunada, Satoshi Hibino, Nobuhisa Iwata, Chie Kadoya, Takashi Aoi
Publikováno v:
Cell Stem Cell. 12(4):487-496
Oligomeric forms of amyloid-β peptide (Aβ) are thought to play a pivotal role in the pathogenesis of Alzheimer's disease (AD), but the mechanism involved is still unclear. Here, we generated induced pluripotent stem cells (iPSCs) from familial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7d0cd9cd08136749a7616dee67eee4
https://nagasaki-u.repo.nii.ac.jp/records/7366
https://nagasaki-u.repo.nii.ac.jp/records/7366
Autor:
Shigeru Nakai, Makoto Kuroda, Yukio Yuzawa, Nobuya Kitaguchi, Masao Kato, Kazunori Kawaguchi, Midori Hasegawa, Yoshiyuki Hiki, Ryuji Hata, Masato Abe, Kazuyoshi Sakai, Takao Senda
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9746373db8d426cc3194e68c258c056
https://doi.org/10.1016/j.jalz.2016.06.1243
https://doi.org/10.1016/j.jalz.2016.06.1243
Autor:
Masahiro Sakanaka, Fang Cao, Kenji Kameda, Ryuji Hata, Kohei Yamauchi, Masahito Ogasawara, Kazutaka Maeyama, Alfred H. Schinkel, Pengxiang Zhu
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism
The organic cation transporters OCT1, 2, and 3 (SLC22A1-3) have been implicated in the elimination of biogenic amines such as histamine. Among them, OCT3 was identified as an uptake-2 transporter, responsible for clearance of histamine. Because incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4d699dbacab9e1224247271982cefd
http://europepmc.org/articles/PMC3463881
http://europepmc.org/articles/PMC3463881
Autor:
David M. Stern, Ryuji Hata, Fang Cao, Tomohiro Matsuyama, Akihiko Taguchi, Yukiko Kasahara, Akie Kikuchi-Taura, Toshihiro Soma, Pengxiang Zhu
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism
Circulating bone marrow-derived immature cells, including endothelial progenitor cells, have been implicated in homeostasis of the microvasculature. Decreased levels of circulating endothelial progenitor cells, associated with aging and/or cardiovasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d13776ea86a02c43db0a2d6c6b8a57
https://doi.org/10.1038/jcbfm.2010.165
https://doi.org/10.1038/jcbfm.2010.165
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
Scientific Reports
Scientific Reports
Induced pluripotent stem cells (iPSCs) are suitable for studying mitochondrial diseases caused by mitochondrial DNA (mtDNA) mutations. Here, we generated iPSCs from a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a43e35acbceacfa2ce18f7cd96aad6
http://link.springer.com/article/10.1038/s41598-018-22721-y
http://link.springer.com/article/10.1038/s41598-018-22721-y