Zobrazeno 1 - 10
of 336
pro vyhledávání: '"Ryuichi Okamoto"'
Autor:
Hiromichi Shimizu, Yuko Aonuma, Shuji Hibiya, Ami Kawamoto, Kento Takenaka, Toshimitsu Fujii, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Ryuichi Okamoto
Publikováno v:
Intestinal Research, Vol 22, Iss 3, Pp 369-377 (2024)
Background/Aims The efficacy and safety of tofacitinib for the treatment of refractory ulcerative colitis (UC) has been demonstrated in clinical trials. Although, a series of reports with real-world evidence of its short-term efficacy and safety prof
Externí odkaz:
https://doaj.org/article/0bad3060fa01414aacaa639d15423421
Autor:
Kazuma Saito, MD, Masanori Kobayashi, MD, PhD, Minato Yokoyama, MD, PhD, Towako Taguchi, MD, PhD, Koichiro Kimura, MD, PhD, Takumi Akashi, MD, PhD, Yasuhisa Fujii, MD, PhD, Ryuichi Okamoto, MD, PhD
Publikováno v:
VideoGIE, Vol 9, Iss 7, Pp 329-332 (2024)
Externí odkaz:
https://doaj.org/article/9adafdff065b47b8acb022d0d5af054b
Autor:
Ami Kawamoto, Kento Takenaka, Shuji Hibiya, Yoshio Kitazume, Hiromichi Shimizu, Toshimitsu Fujii, Eiko Saito, Kazuo Ohtsuka, Ryuichi Okamoto
Publikováno v:
Intestinal Research, Vol 22, Iss 1, Pp 65-74 (2024)
Background/Aims Endoscopic activity confirmed by enteroscopy is associated with poor clinical outcome in Crohn’s disease (CD). We investigated which of the existing biomarkers best reflects endoscopic activity in CD patients including the small bow
Externí odkaz:
https://doaj.org/article/46b984fc0e7642fc856a0709f263f8f5
Autor:
Tharathorn Suwatthanarak, Pariyada Tanjak, Thanawat Suwatthanarak, Onchira Acharayothin, Kullanist Thanormjit, Amphun Chaiboonchoe, Thikhamporn Tawantanakorn, Chainarong Phalanusitthepha, Atthaphorn Trakarnsanga, Asada Methasate, Manop Pithukpakorn, Ryuichi Okamoto, Vitoon Chinswangwatanakul
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Surgical resection followed by indicated adjuvant therapy offers potential curative treatment in colonic adenocarcinoma. Beyond the well-established seed and soil theory of colon cancer progression, the 'normal-appearing' tissues
Externí odkaz:
https://doaj.org/article/078075f7548e41da9f7661cc74a690ac
Autor:
Nobuhiko Ogasawara, Yoshihito Kano, Yosuke Yoneyama, Sakurako Kobayashi, Satoshi Watanabe, Sakura Kirino, Fausto D. Velez-Bravo, Yourae Hong, Aleksandra Ostapiuk, Pavlo Lutsik, Iichiroh Onishi, Shinichi Yamauchi, Yui Hiraguri, Go Ito, Yusuke Kinugasa, Kenichi Ohashi, Mamoru Watanabe, Ryuichi Okamoto, Sabine Tejpar, Shiro Yui
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109247- (2024)
Summary: In normal intestines, a fetal/regenerative/revival cell state can be induced upon inflammation. This plasticity in cell fate is also one of the current topics in human colorectal cancer (CRC). To dissect the underlying mechanisms, we generat
Externí odkaz:
https://doaj.org/article/b7c4b22989424e7d86277299f9e37c54
Autor:
Shun Kaneko, Yasuhiro Asahina, Miyako Murakawa, Seishin Azuma, Kento Inada, Tomohiro Mochida, Keiya Watakabe, Taro Shimizu, Jun Tsuchiya, Masato Miyoshi, Fukiko Kawai-Kitahata, Sayuri Nitta, Marie Takahashi, Tomoyuki Fujioka, Mitsuhiro Kishino, Tatsuhiko Anzai, Sei Kakinuma, Mina Nakagawa, Ryuichi Okamoto
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0297882 (2024)
Background/aimAntiviral hepatitis and systemic therapies for hepatocellular carcinoma (HCC) remarkably progressed in the recent 10 years. This study aimed to reveal the actual transition and changes in the prognosis and background liver disease in no
Externí odkaz:
https://doaj.org/article/86941efca4b84e08aa7173fe99b4bef6
Autor:
Yuki Yonemoto, Yasuhiro Nemoto, Ryo Morikawa, Nana Shibayama, Shigeru Oshima, Takashi Nagaishi, Tomohiro Mizutani, Go Ito, Satoru Fujii, Ryuichi Okamoto
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recent advances in research suggest that aging has a controllable chronic inflammatory disease aspect. Aging systemic T cells, which secrete pro-inflammatory factors, affect surrounding somatic cells, and accelerate the aging process through chronic
Externí odkaz:
https://doaj.org/article/eabcaa9857894d08ba028fb74b77537c
Publikováno v:
Journal of Digestive Endoscopy, Vol 14, Iss 04, Pp 243-244 (2023)
Externí odkaz:
https://doaj.org/article/6939056821bf454cb7a35c34b4907c54
Autor:
Junichi Takahashi, Hady Yuki Sugihara, Shu Kato, Sayaka Nagata, Ryuichi Okamoto, Tomohiro Mizutani
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102374- (2023)
Summary: Current techniques for producing induced-pluripotent-stem-cell-derived mid/hindgut spheroids have faced major hurdles in consistency and reproducibility. Here, we present a protocol that uses mid/hindgut cells to generate homogeneous spheroi
Externí odkaz:
https://doaj.org/article/8fbfcef431e44a2e99a841fee9adb792
Publikováno v:
Endoscopy International Open, Vol 11, Iss 09, Pp E805-E810 (2023)
Externí odkaz:
https://doaj.org/article/ae4a8d54803746858787828eb435bc87