Zobrazeno 1 - 10
of 829
pro vyhledávání: '"Ryuichi Morishita"'
Autor:
Hirotaka Fukami, Jun Morinaga, Hironori Nakagami, Hiroki Hayashi, Yusuke Okadome, Eiji Matsunaga, Tsuyoshi Kadomatsu, Haruki Horiguchi, Michio Sato, Taichi Sugizaki, Keishi Miyata, Daisuke Torigoe, Masashi Mukoyama, Ryuichi Morishita, Yuichi Oike
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-5 (2023)
Abstract Previously, we reported that an ANGPTL3 vaccine is a hopeful therapeutic option against dyslipidemia. In our current study, we assess durability and booster effects of that vaccine over a period representing a mouse’s lifespan. The vaccine
Externí odkaz:
https://doaj.org/article/d22ed8ea37be411eae4aff5e346494ea
Autor:
Yuko Kanemoto, Fumihiro Sanada, Kana Shibata, Yasuo Tsunetoshi, Naruto Katsuragi, Nobutaka Koibuchi, Tetsuhiro Yoshinami, Koichi Yamamoto, Ryuichi Morishita, Yoshiaki Taniyama, Kenzo Shimazu
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1093 (2024)
(1) Background: Periostin (Pn) is a secreted protein found in the extracellular matrix, and it plays a variety of roles in the human body. Physiologically, Pn has a variety of functions, including bone formation and wound healing. However, it has bee
Externí odkaz:
https://doaj.org/article/61b27c6f21f34d2a8e4321e6dec86ea8
Autor:
Kana Shibata, Nobutaka Koibuchi, Fumihiro Sanada, Naruto Katsuragi, Yuko Kanemoto, Yasuo Tsunetoshi, Shoji Ikebe, Koichi Yamamoto, Ryuichi Morishita, Kenzo Shimazu, Yoshiaki Taniyama
Publikováno v:
Cells, Vol 13, Iss 17, p 1410 (2024)
Background: Periostin (POSTN) is a type of matrix protein that functions by binding to other matrix proteins, cell surface receptors, or other molecules, such as cytokines and proteases. POSTN has four major splicing variants (PN1–4), which are pri
Externí odkaz:
https://doaj.org/article/7f3f92684ed748aba17d0ba96d6907e0
Autor:
Hiroki Hayashi, Jiao Sun, Yuka Yanagida, Takako Otera, Jiayu A. Tai, Tomoyuki Nishikawa, Kunihiko Yamashita, Naoki Sakaguchi, Shota Yoshida, Satoshi Baba, Chin Yang Chang, Munehisa Shimamura, Sachiko Okamoto, Yasunori Amaishi, Hideto Chono, Junichi Mineno, Hiromi Rakugi, Ryuichi Morishita, Hironori Nakagami
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Emerging SARS-CoV-2 Omicron variants are highly contagious with enhanced immune escape mechanisms against the initially approved COVID-19 vaccines. Therefore, we require stable alternative-platform vaccines that confer protection against new
Externí odkaz:
https://doaj.org/article/7dffd246ebb04a9ab2662db39fb5d55f
Autor:
Hiroki Hayashi, Jiao Sun, Yuka Yanagida, Takako Otera, Miwa Sasai, Chin Yang Chang, Jiayu A. Tai, Tomoyuki Nishikawa, Kunihiko Yamashita, Naoki Sakaguchi, Shota Yoshida, Satoshi Baba, Munehisa Shimamura, Sachiko Okamoto, Yasunori Amaishi, Hideto Chono, Junichi Mineno, Hiromi Rakugi, Ryuichi Morishita, Masahiro Yamamoto, Hironori Nakagami
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global pandemic. New technologies have been utilized to develop several types of vaccines to prevent the spread of SARS
Externí odkaz:
https://doaj.org/article/97fdc3e097c541348a429867b78bcc6e
Autor:
Nan Ju, Hiroki Hayashi, Munehisa Shimamura, Satoshi Baba, Shota Yoshida, Ryuichi Morishita, Hiromi Rakugi, Hironori Nakagami
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Despite the recent therapeutic developments for the treatment of pulmonary fibrosis, its prognosis is still not well controlled, and a novel therapeutic agent is needed. Recently, the critical role of Toll-like receptors (TLRs) in the pathop
Externí odkaz:
https://doaj.org/article/0c082289de0545358bcbb753757f3729
Autor:
Tsuneo Nakajima, Shuko Takeda, Yuki Ito, Akane Oyama, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Ken Sugimoto, Hideo Shimizu, Munehisa Shimamura, Hiromi Rakugi, Ryuichi Morishita
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Cerebrospinal fluid (CSF) provides a close representation of pathophysiological changes occurring in the central nervous system (CNS); therefore, it has been employed in pathogenesis research and biomarker development for CNS diso
Externí odkaz:
https://doaj.org/article/b3cace8b635b41ebb62f48e596522f9d
Autor:
Tetsuya Tomita, Hiromi Rakugi, Hiroki Hayashi, Ryuichi Morishita, Jiao Sun, Yuka Yanagida, Shota Yoshida, Satoshi Baba, Akiko Tenma, Masayoshi Toyoura, Sotaro Kawabata, Takako Ehara, Ryoko Asaki, Makoto Sakaguchi, Hideki Tomioka, Munehisa Shimamura, Hironori Nakagami
Publikováno v:
RMD Open, Vol 9, Iss 1 (2023)
Objectives Spondyloarthritis (SpA) is known as series of immune-mediated inflammatory disease of the axial and peripheral joints. Human leucocyte antigen (HLA)-B27 is a genetic risk factor for SpA. Recent evidence suggests that the interleukin −17
Externí odkaz:
https://doaj.org/article/f1e439622aa643a9ab0805098beb61be
Autor:
Hironori Nakagami, Tetsuya Matsumoto, Kenji Takazawa, Hisakuni Sekino, Osamu Matsuoka, Satoshi Inoue, Hidetoshi Furuie, Ryuichi Morishita
Publikováno v:
Vaccines, Vol 11, Iss 10, p 1535 (2023)
Pharmacological studies have demonstrated antibody production and infection prevention with an intradermal coronavirus disease 2019 (COVID-19) DNA vaccine (AG0302-COVID-19). This clinical trial aimed to investigate the safety and immunogenicity of hi
Externí odkaz:
https://doaj.org/article/a0f01100bcac438b88a2e1706328b66e
Autor:
Koshiro Monzen, Takanori Watanabe, Toshihiro Okabe, Hisakuni Sekino, Hironori Nakagami, Ryuichi Morishita
Publikováno v:
Viruses, Vol 15, Iss 9, p 1842 (2023)
We investigated humoral immune responses in 222 unvaccinated Japanese people after recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in 2021. Anti-spike-protein IgG antibody levels and neutralizing antibody titers w
Externí odkaz:
https://doaj.org/article/207b52dc218648edbc1b30f453a09461