Zobrazeno 1 - 10 of 55 pro vyhledávání: '"Ryuichi, Tozawa"'
1
Akademický článek
Reversibility of motor dysfunction in the rat model of NGLY1 deficiency
Autor: Makoto Asahina, Reiko Fujinawa, Hiroto Hirayama, Ryuichi Tozawa, Yasushi Kajii, Tadashi Suzuki
Publikováno v: Molecular Brain, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract N-glycanase 1 (NGLY1) deficiency is a rare inherited disorder characterized by developmental delay, hypolacrima or alacrima, seizure, intellectual disability, motor deficits, and other neurological symptoms. The underlying mechanisms of the
Externí odkaz: https://doaj.org/article/a8c595188b1343ea9241c197d3bf8bbd
Zobrazit plný text záznamu
2
Akademický článek
Phenotypic Drug Screening for Dysferlinopathy Using Patient‐Derived Induced Pluripotent Stem Cells
Autor: Yuko Kokubu, Tomoko Nagino, Katsunori Sasa, Tatsuo Oikawa, Katsuya Miyake, Akiko Kume, Mikiko Fukuda, Hiromitsu Fuse, Ryuichi Tozawa, Hidetoshi Sakurai
Publikováno v: Stem Cells Translational Medicine, Vol 8, Iss 10, Pp 1017-1029 (2019)
Abstract Dysferlinopathy is a progressive muscle disorder that includes limb‐girdle muscular dystrophy type 2B and Miyoshi myopathy (MM). It is caused by mutations in the dysferlin (DYSF) gene, whose function is to reseal the muscular membrane. Tre
Externí odkaz: https://doaj.org/article/b07e2c3175334def8fbba6cc177a30d7
Zobrazit plný text záznamu
8
Akademický článek
Plasma cholesterol-lowering and transient liver dysfunction in mice lacking squalene synthase in the liver
Autor: Shuichi Nagashima, Hiroaki Yagyu, Ryuichi Tozawa, Fumiko Tazoe, Manabu Takahashi, Tetsuya Kitamine, Daisuke Yamamuro, Kent Sakai, Motohiro Sekiya, Hiroaki Okazaki, Jun-ichi Osuga, Akira Honda, Shun Ishibashi
Publikováno v: Journal of Lipid Research, Vol 56, Iss 5, Pp 998-1005 (2015)
Squalene synthase (SS) catalyzes the biosynthesis of squalene, the first specific intermediate in the cholesterol biosynthetic pathway. To test the feasibility of lowering plasma cholesterol by inhibiting hepatic SS, we generated mice in which SS is
Externí odkaz: https://doaj.org/article/7b48d2ba7b554bd8aaf864108108d737
Zobrazit plný text záznamu
9
Reversibility of motor dysfunction in the rat model of NGLY1 deficiency
Autor: Reiko Fujinawa, Ryuichi Tozawa, Tadashi Suzuki, Hiroto Hirayama, Yasushi Kajii, Makoto Asahina
Publikováno v: Molecular Brain, Vol 14, Iss 1, Pp 1-12 (2021)
Molecular Brain
N-glycanase 1 (NGLY1) deficiency is a rare inherited disorder characterized by developmental delay, hypolacrima or alacrima, seizure, intellectual disability, motor deficits, and other neurological symptoms. The underlying mechanisms of the NGLY1 phe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc00ebfed4da698cb589b0b38e87732
https://doaj.org/article/a8c595188b1343ea9241c197d3bf8bbd
Zobrazit plný text záznamu
10
Akademický článek
Amelioration of sexual behavior and motor activity deficits in a castrated rodent model with a selective androgen receptor modulator SARM-2f.
Autor: Megumi Morimoto, Yuichiro Amano, Masahiro Oka, Ayako Harada, Hisashi Fujita, Yukiko Hikichi, Ryuichi Tozawa, Masuo Yamaoka, Takahito Hara
Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0189480 (2017)
Sarcopenia and cachexia present characteristic features of a decrease in skeletal muscle mass and strength, anorexia, and lack of motivation. Treatments for these diseases have not yet been established, although selective androgen receptor modulators
Externí odkaz: https://doaj.org/article/ec8c979a56754538966755b08345e3ca
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje