Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ryuhei SANO"'
Autor:
Ryuhei Sano1,2, Kanjiro Ryu2, Tomohiko Sasase1,3 tomohiko.sasase@jt.com, Yuichi Shinozaki1,3, Soon Hui Teoh2, Ayane Yamaguchi2, Kinuko Uno3, Tatsuya Maekawa4, Takeshi Ohta3, Katsuhiro Miyajima2,4
Publikováno v:
Journal of Toxicological Sciences. 2023, Vol. 48 Issue 11, p597-606. 10p.
Autor:
Noriko Suzuki‐Kemuriyama, Akari Abe, Sae Nakane, Kinuko Uno, Shuji Ogawa, Atsushi Watanabe, Ryuhei Sano, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae
Publikováno v:
FEBS Open Bio, Vol 11, Iss 11, Pp 2950-2965 (2021)
Nonalcoholic steatohepatitis (NASH) is often associated with obesity, but some patients develop NASH without obesity. The physiological processes by which nonobese patients develop NASH and cirrhosis have not yet been determined. Here, we analyzed th
Externí odkaz:
https://doaj.org/article/1f1412a381574fb1a0fe5dffddcb28a0
Autor:
Noriko Suzuki-Kemuriyama, Akari Abe, Kiniko Uno, Shuji Ogawa, Atsushi Watanabe, Ryuhei Sano, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-16 (2020)
Abstract Background Nonalcoholic steatohepatitis (NASH) is a form of liver disease characterized by steatosis, necroinflammation, and fibrosis, resulting in cirrhosis and cancer. Efforts have focused on reducing the intake of trans fatty acids (TFAs)
Externí odkaz:
https://doaj.org/article/6f3573c001754a81b616cac0ff325a12
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 4, Pp 770-782 (2020)
Abstract Glucose is the most abundant monosaccharide, and an essential source of energy for most living cells. Glucose transport across the cell membrane is mediated by two types of transporters: facilitative glucose transporters (gene name: solute c
Externí odkaz:
https://doaj.org/article/2d4cb81793024764b14e18e9f4187f80
Autor:
Noriko Suzuki-Kemuriyama, Akari Abe, Kinuko Uno, Shuji Ogawa, Atsushi Watanabe, Ryuhei Sano, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae
Publikováno v:
Lipids in Health and Disease, Vol 21, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/38ec27636a644b1fa234fd727afdd11c
Autor:
Chihiro Okuma, Takeshi Ohta, Hironobu Tadaki, Tatsuya Ishigure, Shohei Sakata, Hideyuki Taniuchi, Ryuhei Sano, Hiromi Hamada, Shinichi Kume, Jun Nishiu, Makoto Kakutani
Publikováno v:
Journal of Pharmacological Sciences, Vol 128, Iss 3, Pp 150-157 (2015)
Aim: Monoacyglycerol acyltransferases (MGATs) are known to play important roles in intestinal TG absorption. In contrast, the role of MGATs in the liver is still unclear. We investigated the effects of JTP-103237, a novel MGAT inhibitor, on hepatic M
Externí odkaz:
https://doaj.org/article/4f84e16fc93843638e297033bf9858ca
Autor:
Akari Abe, Kinuko Uno, Sae Nakane, Ryuhei Sano, Katsuhiro Miyajima, Atsushi Watanabe, Dai Nakae, Noriko Suzuki-Kemuriyama, Shuji Ogawa, Megumi Yuki
Publikováno v:
Fundamental Toxicological Sciences. 8:135-145
Autor:
Yasuka SAIGO, Tomohiko SASASE, Marika TOHMA, Kinuko UNO, Yuichi SHINOZAKI, Tatsuya MAEKAWA, Ryuhei SANO, Katsuhiro MIYAJIMA, Takeshi OHTA
Publikováno v:
Physiological Research; Jun2023, Vol. 72 Issue 3, p371-382, 12p
Autor:
Yasuka Saigo, Tomohiko Sasase, Kinuko Uno, Yuichi Shinozaki, Tatsuya Maekawa, Ryuhei Sano, Yasufumi Toriniwa, Katsuhiro Miyajima, Takeshi Ohta
Publikováno v:
Journal of pharmacological and toxicological methods. 116
An increasing number of patients worldwide are being diagnosed with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis (NAFLD/NASH) because of the growing prevalence of obesity and metabolic disorders. The incidence of NAFLD is higher
Autor:
Hiromi Yoshiuchi, Hironobu Tadaki, Chihiro Okuma, Reina Kakefuda, Takeshi Ohta, Yukihito Ishii, Daisuke Tomimoto, Mariko Maekawa, Ryuhei Sano, Yoshiaki Katsuda, Tomohiko Sasase
Publikováno v:
Biological and Pharmaceutical Bulletin. 42:1906-1912
Tumor necrosis factor-α (TNF-α) converting enzyme/a disintegrin and metalloproteinase domain-containing protein 17 (TACE/ADAM17) is a key sheddase that releases TNF-α from its inactive precursor and is thought as a new drug target to inhibit TNF-