Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Ryuhei Hayashi"'
Autor:
Hiroshi Takayanagi, Ryuhei Hayashi
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 819-825 (2024)
Among the regenerative therapies being put into clinical use, the field of corneal regenerative therapy is one of the most advanced, with several regulatory approved products. This article describes the progress from initial development through to cl
Externí odkaz:
https://doaj.org/article/0e79f37fa0a54b5d8ff95010f6b63658
Autor:
Ryuhei Hayashi, Kenichi Kamata, Marco Gerdol, Yuki Fujii, Takashi Hayashi, Yuto Onoda, Nanae Kobayashi, Satoshi Furushima, Ryuya Ishiwata, Mayuka Ohkawa, Naoko Masuda, Yuka Niimi, Masao Yamada, Daisuke Adachi, Sarkar M. A. Kawsar, Sultana Rajia, Imtiaj Hasan, Somrita Padma, Bishnu Pada Chatterjee, Yuji Ise, Riku Chida, Kayo Hasehira, Nobumitsu Miyanishi, Tatsuya Kawasaki, Yukiko Ogawa, Hideaki Fujita, Alberto Pallavicini, Yasuhiro Ozeki
Publikováno v:
Marine Drugs, Vol 22, Iss 9, p 400 (2024)
We here report the purification of a novel member of the galectin family, the β-galactoside-binding lectin hRTL, from the marine sponge Chondrilla australiensis. The hRTL lectin is a tetrameric proto-type galectin with a subunit molecular weight of
Externí odkaz:
https://doaj.org/article/f0ce2ed3a7014181b5d3c4fb40340a47
Autor:
Tsutomu Imaizumi, Ryuhei Hayashi, Yuji Kudo, Xiaoqin Li, Kaito Yamaguchi, Shun Shibata, Toru Okubo, Tsuyoshi Ishii, Yoichi Honma, Kohji Nishida
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Dry eye syndrome (DES) is a chronic ocular disease that induces epithelial damage to the cornea by decreasing tear production and quality. Adequate treatment options have not been established for severe DES such as Sjogren’s syndrome due t
Externí odkaz:
https://doaj.org/article/8c8b39604a854bff9cdcdd92184c8e66
Autor:
Masahiro Kitao, Ryuhei Hayashi, Kimihito Nomi, Reiko Kobayashi, Tomohiko Katayama, Hiroshi Takayanagi, Akiko Oguchi, Yasuhiro Murakawa, Kohji Nishida
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107016- (2023)
Summary: The conjunctival epithelium consists of conjunctival epithelial cells and goblet cells derived from conjunctival epithelial stem/progenitor cells. However, the source of these cells is not well known because no specific markers for conjuncti
Externí odkaz:
https://doaj.org/article/271c33d1775d4633846db8931c9df2d4
Autor:
Shun Shibata, Ryuhei Hayashi, Toru Okubo, Yuji Kudo, Koichi Baba, Yoichi Honma, Kohji Nishida
Publikováno v:
Regenerative Therapy, Vol 11, Iss , Pp 114-122 (2019)
Introduction: Epithelial–mesenchymal transition (EMT) induces the loss of cell–cell interactions in polarized epithelial cells and converts these cells to invasive mesenchymal-like cells. It is also involved in tissue fibrosis including that occu
Externí odkaz:
https://doaj.org/article/5bd2b62382104a639c279ea299021573
Autor:
Satoko Fujimoto, Ryuhei Hayashi, Susumu Hara, Yuzuru Sasamoto, Jodie Harrington, Motokazu Tsujikawa, Kohji Nishida
Publikováno v:
Regenerative Therapy, Vol 11, Iss , Pp 249-257 (2019)
Introduction: Krüppel-like factor 4 (KLF4) is considered one of the Yamanaka factors, and recently, we and others have shown that KLF4 is one of the transcription factors essential for reprogramming non-human corneal epithelial cells (HCECs) into HC
Externí odkaz:
https://doaj.org/article/6770ae249aa240c19ec372a8b9f84052
Autor:
Shinya Watanabe, Ryuhei Hayashi, Yuzuru Sasamoto, Motokazu Tsujikawa, Bruce R. Ksander, Markus H. Frank, Andrew J. Quantock, Natasha Y. Frank, Kohji Nishida
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102688- (2021)
Summary: Human induced pluripotent stem cells (hiPSCs) can generate a multiplicity of organoids, yet no compelling evidence currently exists as to whether or not these contain tissue-specific, holoclone-forming stem cells. Here, we show that a subpop
Externí odkaz:
https://doaj.org/article/1a8f4230333c43f2bdeb9e01c84932a0
Autor:
Sean Ashworth, Jodie Harrington, Greg M. Hammond, Kiranjit K. Bains, Elena Koudouna, Anthony J. Hayes, James R. Ralphs, Justyn W. Regini, Robert D. Young, Ryuhei Hayashi, Kohji Nishida, Clare E. Hughes, Andrew J. Quantock
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Chondroitin sulfate (CS) is an important component of the extracellular matrix in multiple biological tissues. In cornea, the CS glycosaminoglycan (GAG) exists in hybrid form, whereby some of the repeating disaccharides are dermatan sulfate (DS). The
Externí odkaz:
https://doaj.org/article/db9fa5bfb8664e638206b5dd82603a35
Publikováno v:
Stem Cell Research, Vol 46, Iss , Pp 101868- (2020)
We sought to elucidate how and when the ocular surface ectoderm commits to its differentiation into the corneal epithelium in eye development from human induced pluripotent stem cells (hiPSCs) under the influence of WNT signaling and the actions of B
Externí odkaz:
https://doaj.org/article/eb70685e8b9644069cc0098897e3c933
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 256-265 (2017)
The expression of p63 in surface ectodermal cells during development of the cornea, skin, oral mucosa and olfactory placodes is integral to the process of cellular self-renewal and the maintenance of the epithelial stem cell status. Here, we used TAL
Externí odkaz:
https://doaj.org/article/3416a5ede88747538857f01addfdb3ba