Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Ryuhei Hara"'
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96324 (2014)
OBJECTIVE: Secondary glaucoma is a serious complication in patients with transthyretin (TTR)-related familial amyloidotic polyneuropathy (FAP). We assessed the long-term outcomes and complications of trabeculectomy with mitomycin C (MMC) for secondar
Externí odkaz:
https://doaj.org/article/c87b653e6a144ea79e506d1f463937ec
Autor:
Genki Kudo, Takumi Hirao, Ryuhei Harada, Takatsugu Hirokawa, Yasuteru Shigeta, Ryunosuke Yoshino
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract DNA methylation is an epigenetic mechanism that introduces a methyl group at the C5 position of cytosine. This reaction is catalyzed by DNA methyltransferases (DNMTs) and is essential for the regulation of gene transcription. The DNMT1 and D
Externí odkaz:
https://doaj.org/article/b38df8e4c2e54e1aaa78f6499faa8322
Autor:
Aphinya Suroengrit, Van Cao, Patcharin Wilasluck, Peerapon Deetanya, Kittikhun Wangkanont, Kowit Hengphasatporn, Ryuhei Harada, Supakarn Chamni, Asada Leelahavanichkul, Yasuteru Shigeta, Thanyada Rungrotmongkol, Supot Hannongbua, Warinthorn Chavasiri, Supaporn Wacharapluesadee, Eakachai Prompetchara, Siwaporn Boonyasuppayakorn
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31987- (2024)
Background: Anti-SARS-CoV-2 and immunomodulatory drugs are important for treating clinically severe patients with respiratory distress symptoms. Alpha- and gamma-mangostins (AM and GM) were previously reported as potential 3C-like protease (3CLpro) a
Externí odkaz:
https://doaj.org/article/bd45bb5cd27e42678f2f96acf0b327af
Autor:
Hayato Kosaka, Takashi Harada, Hisahito Ishimatsu, Takahumi Kawamura, Kiyotaka Kurachi, Ryuta Muraki, Ryuhei Hara, Masayoshi Yamamoto, Hiroyuki Konno, Shintaro Ishikawa
Publikováno v:
The Japanese Journal of Gastroenterological Surgery. 50:409-415
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbfaa3ce56e7424812183a591ea8d612
https://doi.org/10.5833/jjgs.2015.0224
https://doi.org/10.5833/jjgs.2015.0224
Autor:
Naoki Suzuki, Makoto Kanzaki, Masashi Koide, Rumiko Izumi, Ryo Fujita, Tadahisa Takahashi, Kazumi Ogawa, Yutaka Yabe, Masahiro Tsuchiya, Masako Suzuki, Ryuhei Harada, Akiyuki Ohno, Hiroya Ono, Naoko Nakamura, Kensuke Ikeda, Hitoshi Warita, Shion Osana, Yoshitsugu Oikawa, Takafumi Toyohara, Takaaki Abe, Muliang Rui, Satoru Ebihara, Ryoichi Nagatomi, Yoshihiro Hagiwara, Masashi Aoki
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0306021 (2024)
Sporadic inclusion body myositis (sIBM) is a muscle disease in older people and is characterized by inflammatory cell invasion into intact muscle fibers and rimmed vacuoles. The pathomechanism of sIBM is not fully elucidated yet, and controversy exis
Externí odkaz:
https://doaj.org/article/f7dc538e6a104a57b7266fa9a8d4f046
Autor:
Yuya Nishida, Sachiko Yanagisawa, Rikuri Morita, Hideki Shigematsu, Kyoko Shinzawa-Itoh, Hitomi Yuki, Satoshi Ogasawara, Ken Shimuta, Takashi Iwamoto, Chisa Nakabayashi, Waka Matsumura, Hisakazu Kato, Chai Gopalasingam, Takemasa Nagao, Tasneem Qaqorh, Yusuke Takahashi, Satoru Yamazaki, Katsumasa Kamiya, Ryuhei Harada, Nobuhiro Mizuno, Hideyuki Takahashi, Yukihiro Akeda, Makoto Ohnishi, Yoshikazu Ishii, Takashi Kumasaka, Takeshi Murata, Kazumasa Muramoto, Takehiko Tosha, Yoshitsugu Shiro, Teruki Honma, Yasuteru Shigeta, Minoru Kubo, Seiji Takashima, Yasunori Shintani
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Antimicrobial resistance to currently available antibiotics requires innovation of antibiotics. Here, the authors identify a critical inhibitory site in an energy-producing enzyme, which can lead to rational design of antibiotics.
Externí odkaz:
https://doaj.org/article/4c52d610a36f4a98ac427d2ed62acfe7
Autor:
Kowit Hengphasatporn, Ryuhei Harada, Patcharin Wilasluck, Peerapon Deetanya, Edwin R. Sukandar, Warinthorn Chavasiri, Aphinya Suroengrit, Siwaporn Boonyasuppayakorn, Thanyada Rungrotmongkol, Kittikhun Wangkanont, Yasuteru Shigeta
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Parallel cascade selection molecular dynamics-based ligand binding-path sampling (LB-PaCS-MD) was combined with fragment molecular orbital (FMO) calculations to reveal the ligand path from an aqueous solution to the SARS-CoV-2 main protease
Externí odkaz:
https://doaj.org/article/bb00934034de4c2c9184feabe2fc5652
Autor:
Takeshi Harada, Hiroyuki Hazama, Kiyotaka Kurachi, Tomoki Sawayanagi, Toshio Nakamura, Hiroyuki Konno, Ryuhei Hara, Koichi Nakamura
Publikováno v:
Nippon Daicho Komonbyo Gakkai Zasshi. 65:70-74
結腸癌術後腹膜再発は播種性再発が多く，予後不良であるが，まれに孤立性に腹膜転移を認める．S状結腸癌術後の直腸膀胱窩孤立性再発に対して再切除を施行し長期生存を得た症例を経
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c4a97ca242084f5c59e67c31bfcd3a2
https://doi.org/10.3862/jcoloproctology.65.70
https://doi.org/10.3862/jcoloproctology.65.70
Autor:
Ryuhei Hara, Masaru Inatani, Hidenobu Tanihara, Takahiro Kawaji, Mikiko Fukushima, Nina Sagara, Yasuya Inomata
Publikováno v:
Current Eye Research. 35:1012-1020
N-acetyl-cysteine (NAC) is a potent antioxidant known to be a precursor of glutathione. The purpose of this study was to investigate the role of NAC in the development of choroidal neovascularization (CNV).CNV was induced in C57BL/6 mice by laser pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bdc056e0f73ad50bbe45e36692c3e66
https://doi.org/10.3109/02713683.2010.500112
https://doi.org/10.3109/02713683.2010.500112
Autor:
Takumi Taketomi, Takunori Yasuda, Rikuri Morita, Jaehyun Kim, Yasuteru Shigeta, Cagla Eroglu, Ryuhei Harada, Fuminori Tsuruta
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Hevin is a secreted extracellular matrix protein that is encoded by the SPARCL1 gene. Recent studies have shown that Hevin plays an important role in regulating synaptogenesis and synaptic plasticity. Mutations in the SPARCL1 gene increase t
Externí odkaz:
https://doaj.org/article/72a771fc41bc4413903860fc7e899dbb