Role of L-asparaginase in acute lymphoblastic leukemia: focus on adult patients

Autor: Rytting ME

Publikováno v: Blood and Lymphatic Cancer: Targets and Therapy, Vol 2012, Iss default, Pp 117-124 (2012)

Michael E RyttingDepartment of Pediatrics and Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USAAbstract: Asparaginase preparations deplete asparagine in acute lymphoblastic leukemia (ALL) blasts. Asparaginase in its various fo

Externí odkaz: https://doaj.org/article/46080141dcf442d894e7520d5603e1b7

ATM-deficient murine thymic T-cell lymphoblastic lymphomas are PTEN-deficient and require AKT signaling for survival.

Autor: An, Joseph B.¹ (AUTHOR), Hathcock, Karen S.¹ (AUTHOR), Steinberg, Seth M.² (AUTHOR), Choo-Wosoba, Hyoyoung M.² (AUTHOR), Hodes, Richard J.^1,3 (AUTHOR) hodesr@31.nia.nih.gov

Publikováno v: PLoS ONE. 12/5/2024, Vol. 19 Issue 12, p1-17. 17p.

Outcomes and adverse events in older acute lymphoblastic Leukemia patients treated with a pediatric-inspired protocol with Pegylated or native Asparaginase.

Autor: Perusini, Maria Agustina¹ (AUTHOR) maria.perusini@uhn.ca, Andrews, Claire¹ (AUTHOR), Atenafu, Eshetu G.² (AUTHOR), Gupta, Vikas¹ (AUTHOR), Maze, Dawn¹ (AUTHOR), Schuh, Andre C.¹ (AUTHOR), Yee, Karen WL.¹ (AUTHOR), Bankar, Aniket¹ (AUTHOR), Davidson, Marta B.¹ (AUTHOR), Richard-Carpentier, Guillaume¹ (AUTHOR), Chan, Steven M.¹ (AUTHOR), Sibai, Jad³ (AUTHOR), Schimmer, Aaron D.¹ (AUTHOR), Minden, Mark D.¹ (AUTHOR), Sibai, Hassan¹ (AUTHOR)

Publikováno v: Hematology. Dec2024, Vol. 29 Issue 1, p1-11. 11p.

Phase I study of intraventricular infusions of autologous ex vivo expanded NK cells in children with recurrent medulloblastoma and ependymoma.

Autor: Khatua S; Department of Pediatrics, MD Anderson Cancer Center, Houston., Cooper LJN; Ziopharm Oncology and MD Anderson Cancer Center, Houston., Sandberg DI; Department of Neurosurgery, MD Anderson Cancer Center, Houston.; Department of Neurosurgery, McGovern Medical School/University of Texas Health Science Center, Houston., Ketonen L; Department of Diagnostic Imaging, MD Anderson Cancer Center, Houston., Johnson JM; Department of Diagnostic Imaging, MD Anderson Cancer Center, Houston., Rytting ME; Department of Pediatrics, MD Anderson Cancer Center, Houston., Liu DD; Department of Biostatistics, University of Texas MD Anderson Cancer center., Meador H; Department of Pediatrics, MD Anderson Cancer Center, Houston., Trikha P; Department of Hematology, Oncology and BMT, Nationwide Children's Hospital, Columbus, Ohio and Department of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Nakkula RJ; Department of Hematology, Oncology and BMT, Nationwide Children's Hospital, Columbus, Ohio and Department of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Behbehani GK; Department of Hematology, Oncology and BMT, Nationwide Children's Hospital, Columbus, Ohio and Department of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Ragoonanan D; Department of Pediatrics, MD Anderson Cancer Center, Houston., Gupta S; Department of Pediatrics, MD Anderson Cancer Center, Houston., Kotrotsou A; Department of Cancer Systems Imaging, MD Anderson Cancer Center, Houston., Idris T; Department of Radiology, Harvard Medical School., Shpall EJ; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston., Rezvani K; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston., Colen R; Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.; Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Zaky W; Department of Pediatrics, MD Anderson Cancer Center, Houston., Lee DA; Department of Hematology, Oncology and BMT, Nationwide Children's Hospital, Columbus, Ohio and Department of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Gopalakrishnan V; Department of Pediatrics, MD Anderson Cancer Center, Houston.

Publikováno v: Neuro-oncology [Neuro Oncol] 2020 Aug 17; Vol. 22 (8), pp. 1214-1225.

Acute myeloid leukaemia.

Autor: Short NJ; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Rytting ME; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Pediatrics-Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Cortes JE; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: jcortes@mdanderson.org.

Publikováno v: Lancet (London, England) [Lancet] 2018 Aug 18; Vol. 392 (10147), pp. 593-606. Date of Electronic Publication: 2018 Aug 02.