Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ryszard Konopiński"'
Autor:
Paulina Kober, Beata Joanna Mossakowska, Natalia Rusetska, Szymon Baluszek, Emilia Grecka, Ryszard Konopiński, Ewa Matyja, Artur Oziębło, Tomasz Mandat, Mateusz Bujko
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13483 (2023)
Meningiomas are common intracranial tumors in adults. Abnormal microRNA (miRNA) expression plays a role in their pathogenesis. Change in miRNA expression level can be caused by impaired epigenetic regulation of miRNA-encoding genes. We found the geno
Externí odkaz:
https://doaj.org/article/a8f58e564a984230ba04fef75c96e61c
Autor:
Łukasz Tomorowicz, Beata Żołnowska, Krzysztof Szafrański, Jarosław Chojnacki, Ryszard Konopiński, Ewa A. Grzybowska, Jarosław Sławiński, Anna Kawiak
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7178 (2022)
In the search for new compounds with antitumor activity, new potential anticancer agents were designed as molecular hybrids containing the structures of a triazine ring and a sulfonamide fragment. Applying the synthesis in solution, a base of new sul
Externí odkaz:
https://doaj.org/article/1f603db029a4475da160b95c2679f6d5
Autor:
Urszula Smietanka, Anna Balcerak, Ewa A. Grzybowska, Tymon Rubel, Mateusz Chmielarczyk, Alicja Trebinska-Stryjewska, Renata Zub, Ryszard Konopiński, Ewelina Macech-Klicka, Maciej Wakula
Publikováno v:
Molecular Biology of the Cell
HAX1 protein is involved in the regulation of apoptosis, cell motility and calcium homeostasis. Its overexpression was reported in several tumors, including breast cancer. This study demonstrates that HAX1 has an impact on collective, but not single-
Autor:
Beata Jagielska, Monika Swiatek, Elzbieta Sarnowska, Agnieszka Tupalska, Tomasz J. Sarnowski, Katarzyna Blachnio, Natalia Zeber-Lubecka, Iga Jancewicz, Szymon Kubala, Joanna Szarkowska, Ewa Grabowska, Ryszard Konopiński, Paulina Oksinska, Sergiusz Markowicz, Janusz A. Siedlecki, Michal Mikula, Jan Walewski, Natalia Rusetska, Bianka Swiderska, Agata Malinowska, Malgorzata Stachowiak, Pawel Cwiek
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4148, p 4148 (2021)
Volume 13
Issue 16
Cancers, Vol 13, Iss 4148, p 4148 (2021)
Volume 13
Issue 16
Growing tumors avoid recognition and destruction by the immune system. During continuous stimulation of tumor-infiltrating lymphocytes (TILs) by tumors, TILs become functionally exhausted
thus, they become unable to kill tumor cells and to produ
thus, they become unable to kill tumor cells and to produ
Autor:
Filip Lyczek, Ryszard Konopiński, Mateusz Chmielarczyk, Maciej Wakula, Ewa A. Grzybowska, Tymon Rubel, Anna Balcerak
Publikováno v:
Bioscience Reports
HCLS1-associated protein X-1 (HAX1) is a multifunctional protein involved in many cellular processes, including apoptosis, cell migration and calcium homeostasis, but its mode of action still remains obscure. Multiple HAX1 protein partners have been
Autor:
Ryszard Konopiński, Anna Balcerak, Alicja Trebinska-Stryjewska, Maciej Wakula, Ewa A. Grzybowska
Publikováno v:
Open Biology
Open Biology, Vol 9, Iss 6 (2019)
Open Biology, Vol 9, Iss 6 (2019)
RNA–protein interactions are crucial for most biological processes in all organisms. However, it appears that the complexity of RNA-based regulation increases with the complexity of the organism, creating additional regulatory circuits, the scope o
Autor:
Hummaira Sadaf, Maciej Ambroziak, Robert Binkowski, Jakkapong Kluebsoongnoen, Ewa Paszkiewicz-Kozik, Jaroslaw Steciuk, Sergiusz Markowicz, Jan Walewski, Elzbieta Sarnowska, Tomasz Jacek Sarnowski, Ryszard Konopinski
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Recent discoveries shed light on molecular mechanisms responsible for classical Hodgkin lymphoma (HL) development and progression, along with features of Hodgkin – Reed and Sternberg cells (HRS). Here, we summarize current knowledge on characterist
Externí odkaz:
https://doaj.org/article/4edb823fea934c3dbeabfbd585ee956d
Autor:
Janusz A. Siedlecki, Maria M. Szwarc, Krzysztof Sobczak, Tomasz J. Sarnowski, Anna Wilczynska, Ryszard Konopiński, Elzbieta Sarnowska, Wlodzimierz J. Krzyzosiak, Ewa A. Grzybowska
Publikováno v:
Nucleic Acids Research
Aberrant expression of DNA polymerase beta, a key enzyme involved in base excision repair, leads to genetic instability and carcinogenesis. Pol beta expression has been previously shown to be regulated at the level of transcription, but there is also
Autor:
Ewelina Macech, Mateusz Chmielarczyk, Anna Balcerak, Ryszard Konopiński, Alicja Trebinska, Jarosław Korczyński, Valery Zayat, Juliusz Wysocki, Magdalena Dziembowska, Elzbieta Sarnowska, Ewa A. Grzybowska
HAX-1, a multifunctional protein involved in the regulation of apoptosis, cell migration, and calcium homeostasis, binds the 3' untranslated region motifs of specific transcripts. This suggests that HAX-1 plays a role in post-transcriptional regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da4355ed6928165c2ecd8942dd80190
https://europepmc.org/articles/PMC4281894/
https://europepmc.org/articles/PMC4281894/
Autor:
Elzbieta Sarnowska, Anna Wilczynska, Ryszard Konopiński, Tomasz J. Sarnowski, Janusz A. Siedlecki, Ewa A. Grzybowska
Publikováno v:
Gene. 371:84-92
Hax-1 protein, which has been studied in mice and humans, shows a potent anti-apoptotic activity and is involved in regulation of cell motility. Cloning of the rat Hax-1 cDNA has revealed seven alternative transcripts, which differ mostly in their 5'