Výsledky vyhledávání - "Ryszard Kinas"

Reinvestigation of the reaction between sodium diethyl phosphite and diethyl phosphorochloridate. Evidence for a SET process in the formation of a direct P(IV)P(IV) bond

Autor: Ryszard Kinas, Wojciech J. Stec, Andrzej Okruszek

Publikováno v: Tetrahedron Letters. 43:7875-7879

Alkali metal salts of diethyl phosphites act as nucleophiles or electron donors in reactions with diethyl phosphorochloridate. Evidence is provided that formation of the direct P(IV)P(IV) bond proceeds via a single electron transfer process (SET)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::125d16bece12695d8e85122a78229624
https://doi.org/10.1016/s0040-4039(02)01916-0

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Studies on the Side-chain Hydroxylation of Ifosfamide and Its Bromo Analogue

Autor: Konrad Misiura, Ryszard Kinas, Kuśnierczyk H

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 12:427-431

Deutero-substituted (alpha,alpha,alpha',alpha'-tetradeuterated) derivatives of ifosfamide (IF-d(4)) and its bromo analogue were synthesised. In vitro metabolic studies showed that microsomal hydroxylation of IF-d(4) is slower than for unlabelled comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed16aa2e986ff02bbf5c4d0c01008bc4
https://doi.org/10.1016/s0960-894x(01)00768-5

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Enantiomeric 2-anilino-2-oxo-1,3,2-oxazaphosphorinanes: Synthesis and NMR-investigation of their non-racemic mixtures

Autor: Andrzej Okruszek, Andrei B. Ouryupin, Mikhail I. Kadyko, Ryszard Kinas, Wojciech J. Stec, Pavel V. Petrovskii, E. I. Fedin

Publikováno v: Tetrahedron: Asymmetry. 6:1813-1824

Enantiomeric R-(−)- and (S)-(+)-2-anilino-2-oxo-1,3,2-oxazaphosphorinanes ( 1 ) have been synthesized by catalytic debenzylation of separated diastereomers of 3-(α-methylbenzyl)-2-anilino-2-oxo-1,3,2-oxazaphosphorinanes. Self-induced diastereomeri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e470ea76654e6a22abc39f780242e9c0
https://doi.org/10.1016/0957-4166(95)00227-g

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ChemInform Abstract: Enantiomeric 2-Anilino-2-oxo-1,3,2-oxazaphosphorinanes: Synthesis and NMR Investigation of Their Non-Racemic Mixtures

Autor: Andrzej Okruszek, Mikhail I. Kadyko, Wojciech J. Stec, Andrei B. Ouryupin, Pavel V. Petrovskii, Ryszard Kinas, E. I. Fedin

Publikováno v: ChemInform. 27

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52fb14608ffd90ff3c2d1ec69e4abe19
https://doi.org/10.1002/chin.199601195

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Effects of alkylating metabolites of ifosfamide and its bromo analogues on DNA of HeLa cells

Autor: Ryszard Kinas, Ewa Ciesielska, Kazimierz Studzian, Leszek Szmigiero

Publikováno v: Biochemical pharmacology. 43(5)

The in vitro cytotoxicity and mechanism of action of three alkylating compounds: an active metabolite of ifosfamide (1, isophosphoramide mustard, N,N'-bis(2-chloroethyl)phosphorodiamidic acid) and its bromo substituted analogues, 2 (one chlorine atom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e58c09f5a451ec060510ecc977df9a5
https://pubmed.ncbi.nlm.nih.gov/1554391

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31P−15N Coupling Constants and 15N/14N Isotope Effects on 31P NMR Chemical Shifts of 2-Phenylamino-2-oxo(-thioxo, -selenoxo)- 4-methyl-1,3,2-dioxaphosphorinanes and Related Compounds

Autor: Ryszard Kinas, Wojciech J. Stec, Willy Gombler

Publikováno v: Zeitschrift für Naturforschung B. 38:815-818

The strong influence of a chalcogen atom (O, S, Se) attached to phosphorus on the spin-spin coupling constant 1J(P-15N) in the family of diastereoisomeric 2-|15N] -phenyl-amino-2X(X = O, S, Se)-4-methyl-l,3,2-dioxaphosphorinanes is demonstrated. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67d246c8d23d108d401e4e9b85a2ba3e
https://doi.org/10.1515/znb-1983-0705

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