Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ryszard Jasztold-Howorko"'
Autor:
Tomasz Gębarowski, Katarzyna Szczaurska-Nowak, Karina Kowalczewska, Beata Tylińska, Ryszard Jasztold-Howorko, Joanna Wietrzyk
Publikováno v:
Acta Poloniae Pharmaceutica - Drug Research. 75:1313-1320
Publikováno v:
Archiv der Pharmazie. 341:677-689
The synthesis and in-vitro biological evaluation of the amide series 4 of 5-(4-chlorobenzoyl)aminoorotic acid 2 are presented. The biological properties of a few 5-(4-chlorobenzoyl)amino-2,6-dihydroxy-N-substituted-4-pyrimidinecarboxamide derivatives
Publikováno v:
Archiv der Pharmazie. 337:434-439
The new and efficient synthesis of the title heterocyclic ring system is described starting from suitable 2-chloro-1, 8-naphthyridines. The synthesized 6H-indolo[2, 3-b][1, 8]naphthyridine derivatives were tested in vitro on 55 tumor cell lines for t
Autor:
Anna Romaniewska, Andrzej Regiec, Ryszard Jasztold‐Howorko, Janina Kuduk-Jaworska, Tadeusz Lis
Publikováno v:
European Journal of Inorganic Chemistry. 2003:4043-4054
Three unknown olivacine derivatives (L-OCH3, L-OH, L-OAc) were synthesized according to a procedure that involves only a few steps, and used as ligands in the synthesis of neutral chelate platinum(II) complexes. The ligands, as well as their platinum
Autor:
Beata, Tylińska, Ryszard, Jasztold-Howorko, Henryk, Mastalarz, Katarzyna, Szczaurska-Nowak, Paulina, Materek, Joanna, Wietrzyk
Publikováno v:
Acta poloniae pharmaceutica. 68(1)
A number of new 1-substituted-6H-pyrido[4,3-b]carbazole derivatives have been synthesized. Nine of the newly obtained compounds were subjected to preliminary in vitro cytostatic activity screening against murine leukemia (L1210), human lung cancer (A
Autor:
Beata, Tylińska, Ryszard, Jasztold-Howorko, Henryk, Mastalarz, Dagmara, Kłopotowska, Beata, Filip, Joanna, Wietrzyk
Publikováno v:
Acta poloniae pharmaceutica. 67(5)
The number of 3'- and 4'-substituted 1-phenyl-6H-pyrido[4,3-b]carbazole derivatives have been synthesized and tested biologically. Eleven of the newly obtained compounds were subjected to the preliminary cytostatic screening for their activity agains
Autor:
Joanna Wietrzyk, Beata Tylińska, Henryk Mastalarz, Katarzyna Szczaurska-Nowak, Ryszard Jasztold-Howorko
Publikováno v:
ChemInform. 39
This study examines the synthesis and cytostatic activity of new 5,6-dimethyl-1-substituted-6H-pyrido[4,3-b]carbazole derivatives. Their structures were confirmed by 1 H-NMR and elemental analysis. Seven of the new compounds were tested by the SRB me
Autor:
Katarzyna Szczaurska-Nowak, Beata Tylińska, Joanna Wietrzyk, Henryk Mastalarz, Ryszard Jasztold-Howorko
Publikováno v:
Archiv der Pharmazie. 341(6)
This study examines the synthesis and cytostatic activity of new 5,6-dimethyl-1-substituted-6H-pyrido[4,3-b]carbazole derivatives. Their structures were confirmed by 1 H-NMR and elemental analysis. Seven of the new compounds were tested by the SRB me
Publikováno v:
Archiv der Pharmazie. 338(11)
Starting from 2-(6-methoxy-1-methyl-9H-carbazol-2-yl)ethylamine 7 and mixed anhydrides of 4-nitrobenzoic acid or 4-methoxybenzoic acid, the corresponding 5,6-dimethyl-9-methoxy-1-(4-substituted phenyl)-6H-pyrido[4,3-b]carbazoles 11a-b, 5,6-dimethyl-9
Publikováno v:
Acta poloniae pharmaceutica. 62(3)
A keystone of this work was a modification of synthesis of the title compounds, which were used as substrates for the preparation of amides 5, 9-methoxyolivacine (4a) and ethyl 9-methoxy-5-methyl-6H-pyrido[4,3-b]carbazole-1-carboxylate (4b) were obta