Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ryszard, Konopiński"'
Autor:
Łukasz, Tomorowicz, Beata, Żołnowska, Krzysztof, Szafrański, Jarosław, Chojnacki, Ryszard, Konopiński, Ewa A, Grzybowska, Jarosław, Sławiński, Anna, Kawiak
Publikováno v:
International journal of molecular sciences. 23(13)
In the search for new compounds with antitumor activity, new potential anticancer agents were designed as molecular hybrids containing the structures of a triazine ring and a sulfonamide fragment. Applying the synthesis in solution, a base of new sul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::528aab1240d9a0c9efdbef12135eabba
https://pubmed.ncbi.nlm.nih.gov/35806186
https://pubmed.ncbi.nlm.nih.gov/35806186
Autor:
Urszula Smietanka, Anna Balcerak, Ewa A. Grzybowska, Tymon Rubel, Mateusz Chmielarczyk, Alicja Trebinska-Stryjewska, Renata Zub, Ryszard Konopiński, Ewelina Macech-Klicka, Maciej Wakula
Publikováno v:
Molecular Biology of the Cell
HAX1 protein is involved in the regulation of apoptosis, cell motility and calcium homeostasis. Its overexpression was reported in several tumors, including breast cancer. This study demonstrates that HAX1 has an impact on collective, but not single-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc876da76cf49678ed73d0bb9c5da1b3
https://doi.org/10.1091/mbc.e19-05-0304
https://doi.org/10.1091/mbc.e19-05-0304
Autor:
Beata Jagielska, Monika Swiatek, Elzbieta Sarnowska, Agnieszka Tupalska, Tomasz J. Sarnowski, Katarzyna Blachnio, Natalia Zeber-Lubecka, Iga Jancewicz, Szymon Kubala, Joanna Szarkowska, Ewa Grabowska, Ryszard Konopiński, Paulina Oksinska, Sergiusz Markowicz, Janusz A. Siedlecki, Michal Mikula, Jan Walewski, Natalia Rusetska, Bianka Swiderska, Agata Malinowska, Malgorzata Stachowiak, Pawel Cwiek
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4148, p 4148 (2021)
Volume 13
Issue 16
Cancers, Vol 13, Iss 4148, p 4148 (2021)
Volume 13
Issue 16
Growing tumors avoid recognition and destruction by the immune system. During continuous stimulation of tumor-infiltrating lymphocytes (TILs) by tumors, TILs become functionally exhausted
thus, they become unable to kill tumor cells and to produ
thus, they become unable to kill tumor cells and to produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2083b0da566e9fc724993183b9ee703
https://pubmed.ncbi.nlm.nih.gov/34439305
https://pubmed.ncbi.nlm.nih.gov/34439305
Autor:
Łukasz Tomorowicz, Beata Żołnowska, Krzysztof Szafrański, Jarosław Chojnacki, Ryszard Konopiński, Ewa A. Grzybowska, Jarosław Sławiński, Anna Kawiak
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7178
In the search for new compounds with antitumor activity, new potential anticancer agents were designed as molecular hybrids containing the structures of a triazine ring and a sulfonamide fragment. Applying the synthesis in solution, a base of new sul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa2b6e1924271fbd08fff85620d51e07
https://doi.org/10.3390/ijms23137178
https://doi.org/10.3390/ijms23137178
Autor:
Filip Lyczek, Ryszard Konopiński, Mateusz Chmielarczyk, Maciej Wakula, Ewa A. Grzybowska, Tymon Rubel, Anna Balcerak
Publikováno v:
Bioscience Reports
HCLS1-associated protein X-1 (HAX1) is a multifunctional protein involved in many cellular processes, including apoptosis, cell migration and calcium homeostasis, but its mode of action still remains obscure. Multiple HAX1 protein partners have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5009674982757dd078bf98ea47782783
https://pubmed.ncbi.nlm.nih.gov/33146709
https://pubmed.ncbi.nlm.nih.gov/33146709
Autor:
Ryszard Konopiński, Anna Balcerak, Alicja Trebinska-Stryjewska, Maciej Wakula, Ewa A. Grzybowska
Publikováno v:
Open Biology
Open Biology, Vol 9, Iss 6 (2019)
Open Biology, Vol 9, Iss 6 (2019)
RNA–protein interactions are crucial for most biological processes in all organisms. However, it appears that the complexity of RNA-based regulation increases with the complexity of the organism, creating additional regulatory circuits, the scope o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6dd713d59dc39c8d34b93d04da2cab5
https://pubmed.ncbi.nlm.nih.gov/31213136
https://pubmed.ncbi.nlm.nih.gov/31213136
Autor:
Janusz A. Siedlecki, Maria M. Szwarc, Krzysztof Sobczak, Tomasz J. Sarnowski, Anna Wilczynska, Ryszard Konopiński, Elzbieta Sarnowska, Wlodzimierz J. Krzyzosiak, Ewa A. Grzybowska
Publikováno v:
Nucleic Acids Research
Aberrant expression of DNA polymerase beta, a key enzyme involved in base excision repair, leads to genetic instability and carcinogenesis. Pol beta expression has been previously shown to be regulated at the level of transcription, but there is also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e77ef0053b9b528eb85aaebf7125dba
Autor:
Ewelina Macech, Mateusz Chmielarczyk, Anna Balcerak, Ryszard Konopiński, Alicja Trebinska, Jarosław Korczyński, Valery Zayat, Juliusz Wysocki, Magdalena Dziembowska, Elzbieta Sarnowska, Ewa A. Grzybowska
HAX-1, a multifunctional protein involved in the regulation of apoptosis, cell migration, and calcium homeostasis, binds the 3' untranslated region motifs of specific transcripts. This suggests that HAX-1 plays a role in post-transcriptional regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da4355ed6928165c2ecd8942dd80190
https://europepmc.org/articles/PMC4281894/
https://europepmc.org/articles/PMC4281894/
Autor:
Elzbieta Sarnowska, Anna Wilczynska, Ryszard Konopiński, Tomasz J. Sarnowski, Janusz A. Siedlecki, Ewa A. Grzybowska
Publikováno v:
Gene. 371:84-92
Hax-1 protein, which has been studied in mice and humans, shows a potent anti-apoptotic activity and is involved in regulation of cell motility. Cloning of the rat Hax-1 cDNA has revealed seven alternative transcripts, which differ mostly in their 5'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa76dfe75632bc1d305f5b0879fd394
https://doi.org/10.1016/j.gene.2005.11.035
https://doi.org/10.1016/j.gene.2005.11.035
Publikováno v:
Biochemical and biophysical research communications. 268(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bffaec1a2d0f198eeafd663919b4ac4
https://pubmed.ncbi.nlm.nih.gov/10652201
https://pubmed.ncbi.nlm.nih.gov/10652201