Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Ryoyo Ikebuchi"'
Autor:
Ehsan Manouchehri Doulabi, Claudia Fredolini, Radiosa Gallini, Liza Löf, Qiujin Shen, Ryoyo Ikebuchi, Louise Dubois, Alireza Azimi, Olivier Loudig, Susanne Gabrielsson, Ulf Landegren, Anders Larsson, Jonas Bergquist, Masood Kamali-Moghaddam
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Surface biotinylation, proximity ligation assays and proteomics are used to identify surface markers of prostate-derived small extracellular vesicles.
Externí odkaz:
https://doaj.org/article/b214fca8bfc4402b831f83b7e55b8e7f
Autor:
Taiki Moriya, Kurumi Kitagawa, Yuuki Hayakawa, Hiroaki Hemmi, Tsuneyasu Kaisho, Satoshi Ueha, Ryoyo Ikebuchi, Ippei Yasuda, Yasutaka Nakanishi, Tetsuya Honda, Koji Matsushima, Kenji Kabashima, Mizuki Ueda, Yutaka Kusumoto, Tatyana Chtanova, Michio Tomura
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102424- (2021)
Summary: Immunogenic tumor cell death enhances anti-tumor immunity. However, the mechanisms underlying this effect are incompletely understood. We established a system to induce tumor cell death in situ and investigated its effect on dendritic cell (
Externí odkaz:
https://doaj.org/article/ebf7407913484d49baa219362ed48299
Autor:
Ippei Yasuda, Tomoko Shima, Taiki Moriya, Ryoyo Ikebuchi, Yutaka Kusumoto, Akemi Ushijima, Akitoshi Nakashima, Michio Tomura, Shigeru Saito
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Dendritic cells (DCs) are essential for successful embryo implantation. However, the properties of uterine DCs (uDCs) during the implantation period are not well characterized. In this study, we investigated the dynamic changes in the uDC phenotypes
Externí odkaz:
https://doaj.org/article/b3b6cc818a184664b1db10ce85eaf532
Autor:
Tomohiro Okagawa, Satoru Konnai, Asami Nishimori, Naoya Maekawa, Shinya Goto, Ryoyo Ikebuchi, Junko Kohara, Yasuhiko Suzuki, Shinji Yamada, Yukinari Kato, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
Veterinary Research, Vol 49, Iss 1, Pp 1-12 (2018)
Abstract Bovine leukemia virus (BLV) is a retrovirus that infects B cells in cattle and causes bovine leukosis after a long latent period. Progressive exhaustion of T cell functions is considered to facilitate disease progression of BLV infection. Pr
Externí odkaz:
https://doaj.org/article/f4608a6016e34b98a040c72bdc125abb
Autor:
Naoya Maekawa, Satoru Konnai, Satoshi Takagi, Yumiko Kagawa, Tomohiro Okagawa, Asami Nishimori, Ryoyo Ikebuchi, Yusuke Izumi, Tatsuya Deguchi, Chie Nakajima, Yukinari Kato, Keiichi Yamamoto, Hidetoshi Uemura, Yasuhiko Suzuki, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Immunotherapy targeting immune checkpoint molecules, programmed cell death 1 (PD-1) and PD-ligand 1 (PD-L1), using therapeutic antibodies has been widely used for some human malignancies in the last 5 years. A costimulatory receptor, PD-1, i
Externí odkaz:
https://doaj.org/article/0b6a85047df74aa79f76ad9d2aea9699
Autor:
Ryoyo Ikebuchi, Maika Fujimoto, Yasutaka Nakanishi, Hiromi Okuyama, Taiki Moriya, Yutaka Kusumoto, Michio Tomura
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Regulatory T cells (Tregs) migrate between lymphoid and peripheral tissues for maintaining immune homeostasis. Tissue-specific function and functional heterogeneity of Tregs have been suggested, however, correlation between them and inter-tissue move
Externí odkaz:
https://doaj.org/article/7c17c1e5bcd24cd2a8cb17e3284d9287
Autor:
Tomohiro Okagawa, Satoru Konnai, Asami Nishimori, Naoya Maekawa, Ryoyo Ikebuchi, Shinya Goto, Chie Nakajima, Junko Kohara, Satoshi Ogasawara, Yukinari Kato, Yasuhiko Suzuki, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Blockade of immunoinhibitory molecules, such as programmed death-1 (PD-1)/PD-ligand 1 (PD-L1), is a promising strategy for reinvigorating exhausted T cells and preventing disease progression in a variety of chronic infections. Application of this the
Externí odkaz:
https://doaj.org/article/ece38efd907b407198c686f3f45704db
Autor:
Asami Nishimori, Satoru Konnai, Tomohiro Okagawa, Naoya Maekawa, Ryoyo Ikebuchi, Shinya Goto, Yamato Sajiki, Yasuhiko Suzuki, Junko Kohara, Satoshi Ogasawara, Yukinari Kato, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174916 (2017)
Programmed death-1 (PD-1), an immunoinhibitory receptor on T cells, is known to be involved in immune evasion through its binding to PD-ligand 1 (PD-L1) in many chronic diseases. We previously found that PD-L1 expression was upregulated in cattle inf
Externí odkaz:
https://doaj.org/article/014030c4e1884130b43fa0bb10f61216
Autor:
Naoya Maekawa, Satoru Konnai, Tomohiro Okagawa, Asami Nishimori, Ryoyo Ikebuchi, Yusuke Izumi, Satoshi Takagi, Yumiko Kagawa, Chie Nakajima, Yasuhiko Suzuki, Yukinari Kato, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157176 (2016)
Spontaneous cancers are common diseases in dogs. Among these, some malignant cancers such as oral melanoma, osteosarcoma, hemangiosarcoma, and mast cell tumor are often recognized as clinical problems because, despite their high frequencies, current
Externí odkaz:
https://doaj.org/article/e76b594809d2451abbcc39bb923feb6f
Autor:
Naoya Maekawa, Satoru Konnai, Ryoyo Ikebuchi, Tomohiro Okagawa, Mami Adachi, Satoshi Takagi, Yumiko Kagawa, Chie Nakajima, Yasuhiko Suzuki, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98415 (2014)
Programmed death 1 (PD-1), an immunoinhibitory receptor, and programmed death ligand 1 (PD-L1), its ligand, together induce the "exhausted" status in antigen-specific lymphocytes and are thus involved in the immune evasion of tumor cells. In this stu
Externí odkaz:
https://doaj.org/article/274bebba5da1467db46e1e7a242b93a0