Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ryouichi Hamasuna"'
Autor:
Tsuyoshi Fukushima, Hiroaki Kataoka, Shuichiro Uchiyama, Koki Nagaike, Hiroyuki Tanaka, Seiji Naganuma, Kazuo Chijiiwa, Hiroshi Itoh, Ryouichi Hamasuna
Publikováno v:
Gut. 56:215-226
Background: Hepatocyte growth factor activator inhibitor type 2-related small peptide (H2RSP) is a small nuclear protein abundantly expressed in the gastrointestinal epithelium. However, its functions remain unknown. Aims: To investigate the expressi
Autor:
Tsuyoshi Fukushima, Shunro Uchinokura, Shinichiro Wakisaka, Shinichi Nakano, Hiroaki Kataoka, Yutaka Akiyama, Hiroshi Itoh, Ryouichi Hamasuna, Shiro Miyata
Publikováno v:
Cancer Letters. 227:83-93
Hepatocyte growth factor activator inhibitor type-1 (HAI-1) is an integral-membrane proteinase inhibitor. In this study, we examined the effects of HAI-1 on human glioblastoma cells. Two glioblastoma cell lines (YKG-1, U251) were stably transfected w
Autor:
Ryouichi Hamasuna, Takeshi Shimomura, Naomi Kitamura, Yoshitsugu Nuki, Hiroshi Itoh, Seiji Naganuma, Hiroaki Kataoka
Publikováno v:
Biochemical and Biophysical Research Communications. 290:1096-1100
Hepatocyte growth factor activator inhibitor type 2 (HAI-2) is a serine proteinase inhibitor containing two Kunitz-type inhibitor domains, initially identified as a potent inhibitor of hepatocyte growth factor activator (HGFA). In a previous study (B
Autor:
Naomi Kitamura, Masashi Koono, Hiroaki Kataoka, Jing Yan Meng, Hiroshi Itoh, Ryouichi Hamasuna
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1519:92-95
Hepatocyte growth factor (HGF) activator inhibitor type 1 (HAI-1) and type 2 (HAI-2) were recently discovered as specific inhibitors of HGF activator. Each of them contains two Kunitz-type serine protease inhibitor domains and a transmembrane domain,
Autor:
Hiroshi Itoh, Masamichi Yamauchi, Ryouichi Hamasuna, Masashi Koono, Hiroaki Kataoka, Naomi Kitamura
Publikováno v:
European Journal of Biochemistry. 267:3351-3359
Hepatocyte growth factor activator inhibitor type 1 (HAI-1) and type 2 (HAI-2) are recently discovered Kunitz-type serine protease inhibitors which can be purified and cloned from human stomach cancer cell line MKN45 as specific inhibitors against he
Autor:
Hiroshi Itoh, Masamichi Yamauchi, Ryouichi Hamasuna, Masashi Koono, Hiroaki Kataoka, Naomi Kitamura, Keiji Miyazawa
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1491:295-302
A cDNA encoding mouse hepatocyte growth factor activator (HGFA) has been cloned by RT-PCR, based on the screening result from the database of expressed sequence tags. Subsequently, its gene was cloned from a mouse genomic bacterial artificial chromos
Autor:
Masashi Koono, Yukifumi Nawa, Masaki Tomita, Ryouichi Hamasuna, Hiroaki Kataoka, Hiroshi Itoh, Naomi Kitamura
Publikováno v:
Scopus-Elsevier
Hepatocyte growth factor (HGF) activator inhibitor type 1 (HAI-1) and type 2 (HAI-2) are new Kunitz-type serine protease inhibitors that were recently purified and cloned from the human stomach cancer cell line MKN45 as specific inhibitors against HG
Publikováno v:
Gastroenterology. 118:60-69
Background & Aims: Intestinal trefoil factor (ITF) has a role in gastrointestinal mucosal integrity and the repair of damaged mucosa. However, little is known about its role in tumors. To analyze the role of ITF in colon carcinomas, overexpression of
Autor:
Ryouichi Hamasuna, Takuzou Moriyama, Hiroaki Kataoka, Masashi Koono, Hiroshi Itoh, Motoharu Seiki
Publikováno v:
International Journal of Cancer. 82:274-281
Hepatocyte growth factor/scatter factor (HGF/SF) contributes to the malignant progression of human gliomas. We investigated the effect of HGF/SF on matrix metalloproteinase-2 (MMP-2), membrane type 1 matrix metalloproteinase (MT1-MMP) and tissue inhi
Autor:
Shinichi Nakano, Etsuo Yoshida, Kiyotaka Yokogami, Tetsuro Sameshima, Ryouichi Hamasuna, Takuzou Moriyama, Hiroaki Kataoka, Tsutomu Iseda, Masashi Koono, Shinichiro Wakisaka
Publikováno v:
Clinical and Experimental Metastasis. 17:873-879
Several lines of evidence indicate that hepatocyte growth factor/scatter factor (HGF/SF) and its receptor, c-Met, may play an important role in progression of human glioma. In this study, effects of HGF/SF on urokinase- type plasminogen activator (uP