Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ryotarou Mitsumata"'
Autor:
Masanori Shiohara, Saori Suzuki, Shintaro Shichinohe, Hirohito Ishigaki, Misako Nakayama, Naoki Nomura, Masashi Shingai, Toshiki Sekiya, Marumi Ohno, Sayaka Iida, Naoko Kawai, Mamiko Kawahara, Junya Yamagishi, Kimihito Ito, Ryotarou Mitsumata, Tomio Ikeda, Kenji Motokawa, Tomoyoshi Sobue, Hiroshi Kida, Kazumasa Ogasawara, Yasushi Itoh
Publikováno v:
Vaccine. 40(30):4026-4037
The All-Japan Influenza Vaccine Study Group has been developing a more effective vaccine than the current split vaccines for seasonal influenza virus infection. In the present study, the efficacy of formalin- and/or β-propiolactone-inactivated whole
Autor:
Fumihito Muro, Tomoyoshi Sobue, Yasushi Itoh, Yuya Mori, Naoki Nomura, Yoichiro Kino, Chimuka Handabile, Hiroki Kitayama, Ryotarou Mitsumata, Hironori Hatanaka, Kazuhiko Kimachi, Ryosuke Omori, Tomohiro Nishimura, Misako Nakayama, Kazumasa Ogasawara, Brendon Y. Chua, Cong Thanh Nguyen, Marumi Ohno, David C. Jackson, Katherine Kedzierska, Masafumi Endo, Toshiki Sekiya, Marios Koutsakos, Yuki Ohara, Saori Suzuki, Masashi Shingai, Lorena E. Brown, Tomio Ikeda, Daisuke Fujikura, Hirohito Ishigaki, Hiroshi Kida
Publikováno v:
Vaccine. 39(29):3940-3951
Current detergent or ether-disrupted split vaccines (SVs) for influenza do not always induce adequate immune responses, especially in young children. This contrasts with the whole virus particle vaccines (WPVs) originally used against influenza that
Autor:
Mayumi Sasada, Hironori Hatanaka, Marumi Ohno, Lorena E. Brown, Hiroshi Kida, Yuki Ohara, Daisuke Fujikura, Hiroki Kitayama, Masafumi Endo, Naoki Nomura, Tomio Ikeda, Masashi Shingai, Tomohiro Nishimura, Kazumasa Ogasawara, Tomoyoshi Sobue, Kenji Motokawa, Yoichiro Kino, Takuji Daito, Edin J Mifsud, Saori Suzuki, Yasushi Itoh, Ryotarou Mitsumata, Toshiki Sekiya
Publikováno v:
Vaccine. 37:2158-2166
In contrast to current ether- or detergent-disrupted "split" vaccines (SVs) for influenza, inactivated whole influenza virus particle vaccines (WPVs) retain the original virus structure and components and as such may confer similar immunity to natura
Autor:
Kaoru Matsuura, Kouhei Kiyonaga, Kiyoteru Nozaki, Yasuharu Otsubo, Atsunobu Muneoka, Ryotarou Mitsumata, Yoshihiro Takahashi, Shozo Shoji, Mitsuaki Masuyama, Shogo Misumi, Nobutoki Takamune, Seizo Yashiro
Publikováno v:
Biochemical and Biophysical Research Communications. 443:301-307
The presence of anti-CCR5 and anti-HIV-1 envelope glycoprotein (ENV) gp41 antibodies (Abs) at sites of HIV-1 exposure was effective in preventing its transmission to HIV-1-exposed seronegative (ESN) subjects. Here, we design an immunogen that can ind
Publikováno v:
Biochemical and Biophysical Research Communications. 377:617-621
Our previous study demonstrated that the immunization with a cycloimmunogen derived from extracellular loop-2 (ECL-2) of CCR5 (cDDR5) attenuated acute phase of CCR5-tropic simian-human immunodeficiency virus (SHIV)(SF162P3) replication in vivo. Altho
Autor:
Takeshi Arakawa, Takeshi Miyata, Hirochika Kawakami, Senji Tafuku, Masayuki Tadano, Tomomitsu Sewaki, Ryotarou Mitsumata, Tetsuya Harakuni
Publikováno v:
Microbes and infection. 14(2)
Ectodomain of Japanese encephalitis virus (JEV) E protein [domains I through III (D1–3), domains I and II (D1–2) and domain III (D3)] and the nonstructural protein 1 (NS1) were expressed in Escherichia coli , and administered to BALB/c mice via t
Autor:
Koichiro Fukuzaki, Takayuki Sukamoto, Shozo Shoji, Hirokazu Matsumoto, Atsunobu Muneoka, Nobutoki Takamune, Ryotarou Mitsumata, Daisuke Nakayama, Shogo Misumi, Yoshihiro Takahashi, Norimitsu Urata, Mitsuaki Masuyama
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(10)
Effective uptake of Ags by specialized M cells of gut-associated lymphoid tissues is an important step in inducing efficient immune responses after oral vaccination. Although stable nontoxic small molecule mimetics of lectins, such as synthetic multi