Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Ryotaro Kuroda"'
Autor:
Naoyuki Kawao, Hisao Ikeda, Tomoko Kitano, Ryotaro Kuroda, Fumiko Sekiguchi, Kazuo Kataoka, Yoshihisa Kamanaka, Atsufumi Kawabata
Publikováno v:
Journal of Pharmacological Sciences, Vol 94, Iss 3, Pp 277-285 (2004)
Protease-activated receptors (PARs) 1 and 2 are expressed in capsaicin-sensitive sensory neurons, being anti- and pro-nociceptive, respectively. Given the possible cross talk between PAR-2 and capsaicin receptors, we investigated if PAR-2 activation
Externí odkaz:
https://doaj.org/article/7463b50f7920413ea301f9d1155acb6e
Publikováno v:
Asia Communications and Photonics Conference/International Conference on Information Photonics and Optical Communications 2020 (ACP/IPOC).
We propose a modulation format conversion method from two QPSK signals to a 16QAM signal by using phase-sensitive amplification and IQ modulation. Numerical simulation reveals that error-free conversion can be achieved. © 2020 The Author(s)
Autor:
Hiroyuki Nishikawa, Satoko Kubo, Kenzo Kawai, Atsufumi Kawabata, Yumiko Nakaya, Ryotaro Kuroda, Fumiko Sekiguchi, Naoyuki Kawao, Tsuyoshi Ishiki
Publikováno v:
Life Sciences. 75:2689-2702
Receptor-activating peptides for protease-activated receptors (PARs) 1 or 2 enhance gastric mucosal blood flow (GMBF) and protect against gastric mucosal injury in rats. We thus examined and characterized the effects of PAR-1 and PAR-2 agonists on th
Autor:
Takashi Masuko, Akiko Ogawa, Koichi Iwata, Atsufumi Kawabata, Ryotaro Kuroda, Naoyuki Kawao, Fumiko Sekiguchi, Hideki Itoh
Publikováno v:
NeuroReport. 15:1617-1621
To clarify involvement of protease-activated receptor-2 (PAR-2) in parotid pain, we examined whether PAR-2 activation in the parotid gland could activate trigeminal nociceptive neurons in anesthetized rats, by analyzing immunoreactive Fos as a nocice
Autor:
Toru Kanke, Naohiro Saito, Satoko Kubo, Atsufumi Kawabata, Morley D. Hollenberg, Naoyuki Kawao, Tsuyoshi Ishiki, Ryotaro Kuroda, Fumiko Sekiguchi
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 311:402-410
We characterized the tracheal and bronchial relaxation caused by proteinase-activated receptor-2 (PAR-2) activation in ddY mice and/or in wild-type and PAR-2-knockout mice of C57BL/6 background. Ser-Leu-Ile-Gly-Arg-Leu-amide (SLIGRL-NH(2)) and Thr-Ph
Autor:
M. Saka, Atsufumi Kawabata, Mototsugu Kabeya, Robin Plevin, Daiki Yonezawa, Masahiro Iwaki, Satoko Kubo, Kousaku Katsura, Ryotaro Kuroda, Toru Kanke, Tsuyoshi Ishiki, Fumiko Sekiguchi
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 309:1098-1107
To develop potent and metabolically stable agonists for protease-activated receptor-2 (PAR-2), we prepared 2-furoylated (2f) derivatives of native PAR-2-activating peptides, 2f-LIGKV-OH, 2f-LIGRL-OH, 2f-LIGKV-NH(2), and 2f-LIGRL-NH(2), and systematic
Autor:
Ryotaro Kuroda, Takashi Masuko, Yumiko Nakaya, Hiroyuki Nishikawa, Atsufumi Kawabata, Kenzo Kawai, Mariko Wakisaka
Publikováno v:
British Journal of Pharmacology. 140:247-254
Agonists for protease-activated receptor-2 (PAR-2) cause hypotension and an increase in gastric mucosal blood flow (GMBF) in vivo. We thus studied the mechanisms underlying the circulatory modulation by PAR-2 activation in vivo, especially with respe
Autor:
Atsufumi Kawabata, Naoyuki Kawao, Hiroyuki Nishikawa, Ryotaro Kuroda, Nanae Nagata, Minoru Nishida, Yuriko Sakaguchi, Kenzo Kawai, Naoki Arizono
Publikováno v:
Life Sciences. 71:2435-2446
Protease-activated receptor-2, a G protein-coupled receptor activated by serine proteases such as trypsin, tryptase and coagulation factors VIIa and Xa, modulates pancreatic and salivary exocrine secretion. In the present study, we examined the distr
Autor:
Yoshio Shigenaga, Vidya Varathan, Motohide Takemura, Atsufumi Kawabata, Fusami Gojyo, Ryotaro Kuroda, Shinichi Sugiyo
Publikováno v:
Journal of Neuroscience Research. 68:479-488
We examined the effects of epidural electrical stimulation of primary (SI) and secondary (SII) somatosensory cortex on expression of c-Fos protein in rat medullary dorsal horn neurons (Vc; trigeminal nucleus caudalis) in response to formalin-induced