Výsledky vyhledávání - "Ryotaro Kamitsubo"

Gene correction by 5′-tailed duplexes with short editor oligodeoxyribonucleotides

Autor: Ryotaro Kamitsubo, Hidehiko Kawai, Kentaro Yazama, Yuri Yanai, Hiroyuki Kamiya

Publikováno v: Journal of Bioscience and Bioengineering. 132:552-559

Various diseases, including cancer, are caused by genetic mutations. A 5'-tailed duplex (TD) DNA, consisting of a long single-stranded (ss) editor DNA and a short (∼35-base) ss assistant oligodeoxyribonucleotide, can introduce a base-substitution i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c6dca29a2c746136ff1e2fe188de70
https://doi.org/10.1016/j.jbiosc.2021.08.012

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Correction of monomeric enhanced green fluorescent protein (mEGFP) gene by short 5'-tailed duplexes

Autor: Hidehiko Kawai, Ryotaro Kamitsubo, Hiroyuki Kamiya

Publikováno v: Journal of bioscience and bioengineering. 134(3)

Mutations of important genes elicit various disorders, including cancer. Recently, a new version of a 5'-tailed duplex (short TD), consisting of a ∼100-base editor strand containing the wild-type sequence and a ∼35-base assistant strand, was show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93196c999c29a191b7ce6317193dcfea
https://pubmed.ncbi.nlm.nih.gov/35850760

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