Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ryota Kajihara"'
Wnt signaling blockade is essential for maintaining the pluripotency of chicken embryonic stem cells
Autor:
Ryota Kajihara, Ryo Ezaki, Kennosuke Ichikawa, Tenkai Watanabe, Takumi Terada, Mei Matsuzaki, Hiroyuki Horiuchi
Publikováno v:
Poultry Science, Vol 103, Iss 2, Pp 103361- (2024)
ABSTRACT: Activation of Wnt/β-catenin signaling supports the self-renewal of mouse embryonic stem cells. We aimed to understand the effects of Wnt signaling activation or inhibition on chicken embryonic stem cells (chESCs), as these effects are larg
Externí odkaz:
https://doaj.org/article/389f611ad7c749fc8b74dccae9b61636
Publikováno v:
Chemistry Letters. 48:295-298
Cellular uptake of rigid and flexible supramolecular hemoprotein assemblies formed by cytochrome b562 was investigated. Multivalent cell-penetrating tags on the protein surfaces of the assemblies i...
Publikováno v:
Tetrahedron Letters. 59:1906-1908
Diazo compounds are frequently used as precursors of metal carbenoids and act as soft nucleophiles even without the use of metal catalysts. The resulting diazonium species may also be trapped by various nucleophiles. The introduction of an iodine fun
Publikováno v:
Chemical communications (Cambridge, England). 55(11)
Engineered cytochrome b562, a small hemoprotein, with an externally-attached heme moiety via a moderately long linker at a suitable position predominantly forms a thermodynamically stable ring-shaped trimer in dilute solution. In an equilibrium betwe
Publikováno v:
Journal of inorganic biochemistry. 193
Electron transfer (ET) events occurring within metalloprotein complexes are among the most important classes of reactions in biological systems. This report describes a photoinduced electron transfer between Zn porphyrin and Fe porphyrin within a sup
Autor:
Takashi Hayashi, Nishiki Fujimaki, Hiroki Watanabe, Ryota Kajihara, Takayuki Uchihashi, Koji Oohora
Publikováno v:
Journal of the American Chemical Society. 140(32)
A supramolecular assembly of units of cytochrome b562 with externally attached heme having intermolecular linkages formed via the heme–heme pocket interaction was investigated in an effort to construct a well-defined structure. The engineered site
Autor:
Tetsuhiro Nemoto, Shingo Harada, Naohiko Anzai, Risa Muramoto, Promsuk Jutabha, Ryota Kajihara
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(10)
p-Boronophenylalanine (l-BPA) is applied in clinical settings as a boron carrier for boron neutron capture therapy (BNCT) to cure malignant melanomas. Structural modification or derivatization of l-BPA, however, to improve its uptake efficiency into
Publikováno v:
Organic letters. 19(24)
Molecular iodine catalyzes a cyclization of N-aryl-2-alkynylanilines, which proceeds through the iodocyclization of 2-alkynylanilines followed by the protodeiodination of the iodocyclized intermediates at room temperature. Furthermore, the molecular
Publikováno v:
ChemInform. 47
A domino cyclization of α-alkoxyalkyl ortho-alkynylaryl ethers and electron-rich arenes affords benzofurans.
Publikováno v:
Organic letters. 18(16)
A domino synthesis of benzofurans with the modification of side chains from α-alkoxyalkyl o-alkynylaryl ethers (n = 0) and electron-rich arenes has been developed. In the present domino reaction, which would proceed via the α-alkoxyalkylation of ar