Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ryota, Nakazato"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The introduction of small insertion/deletion (indel) mutations in the coding region of genes by the site-specific nucleases such as Cas9 allows researchers to obtain frameshift null mutants. Technically simple and costly reasonable genotypin
Externí odkaz:
https://doaj.org/article/c7dbb31e42874e39a564522995334e5a
Publikováno v:
Journal of Cell Science; Aug2024, Vol. 137 Issue 16, p1-17, 17p
Autor:
Takeshi Takarada, Noritaka Nakamichi, Ryota Nakazato, Takami Kakuda, Hiroshi Kokubo, Shinsuke Ikeno, Saki Nakamura, Nobuyuki Kuramoto, Eiichi Hinoi, Yukio Yoneda
Publikováno v:
Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 89-95 (2016)
We have shown marked promotion of both proliferation and neuronal differentiation in pluripotent P19 cells exposed to the green tea amino acid theanine, which is a good substrate for SLC38A1 responsible for glutamine transport. In this study, we eval
Externí odkaz:
https://doaj.org/article/31db8f1b66054700b513d3e6fe05e350
Publikováno v:
Cilia: From Mechanisms to Disease-Part A ISBN: 9780443185861
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c96cf2d842ea75869997870ceb32add1
https://doi.org/10.1016/bs.mcb.2022.10.003
https://doi.org/10.1016/bs.mcb.2022.10.003
Autor:
Takeshi Takarada, Noritaka Nakamichi, Takami Kakuda, Ryota Nakazato, Hiroshi Kokubo, Shinsuke Ikeno, Saki Nakamura, Eiichi Hinoi, Yukio Yoneda
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 3, Pp 292-297 (2015)
Posttraumatic stress disorder is a long-lasting psychiatric disease with the consequence of hippocampal atrophy in humans exposed to severe fatal stress. We demonstrated a positive correlation between the transient decline of 5-bromo-2′-deoxyuridin
Externí odkaz:
https://doaj.org/article/4b6a8ef0a7094f46af4753039e9a2f5a
Autor:
Ryota Nakazato, Katsuji Yoshioka, Shan Liu, Lu Zhang, Guohua Ding, Kai Zhu, Zhaowei Chen, Qiang Fu, Qi Yan, Bo Diao, Huiming Wang, Xiaogang Li, Dou Fu
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-16 (2020)
Communications Biology
Communications Biology
Renal fibrosis is controlled by profibrotic and antifibrotic forces. Exploring anti-fibrosis factors and mechanisms is an attractive strategy to prevent organ failure. Here we identified the JNK-associated leucine zipper protein (JLP) as a potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa6a6ed85a8a675154b5b1bb98ca5112
http://link.springer.com/article/10.1038/s42003-020-1008-z
http://link.springer.com/article/10.1038/s42003-020-1008-z
Publikováno v:
Journal of Pharmacological Sciences, Vol 116, Iss 4, Pp 350-361 (2011)
Abstract.: Clock genes are believed to play a pivotal role in the generation and oscillation of circadian rhythm as a central clock in the hypothalamic suprachiasmatic nucleus in the mammalian brain. In this study, mRNA expression was for the first t
Externí odkaz:
https://doaj.org/article/b8bddc7fac8c446b9287911e4dc5c02a
Autor:
Masaki Fukui, Shusuke Ozawa, Noritaka Nakamichi, Ryota Nakazato, Takeshi Takarada, Yukio Yoneda
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 1, Pp 45-55 (2011)
We have previously shown the functional expression of GABAB receptors (GABABR) composed of GABABR1 and GABABR2 subunits with ability to promote proliferation and neuronal differentiation in cultured neural progenitor cells (NPC) isolated from embryon
Externí odkaz:
https://doaj.org/article/16739eb73ff045fc9f5e98904847da49
Autor:
Toshitaka Oohashi, Shunpei Tsukamoto, Mari Kaneko, Koichi Fujikawa, Shioi Go, Saki Nakamura, Ryota Nakazato, Yukio Yoneda, Daisuke Yamada, Ikue Tosa, Miki Kou, Takeshi Takarada, Kenji Kawabe, Eiichi Hinoi, Mitsuaki Ono
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-11 (2019)
Communications Biology
Communications Biology
The pathophysiological role of mammalian target of rapamycin complex 1 (mTORC1) in neurodegenerative diseases is established, but possible therapeutic targets responsible for its activation in neurons must be explored. Here we identified solute carri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa7b92769c9765307c30fc6cc3074ca
http://link.springer.com/article/10.1038/s42003-019-0582-4
http://link.springer.com/article/10.1038/s42003-019-0582-4
Autor:
Ryo Fukumori, Takeshi Takarada, Ryota Nakazato, Koichi Fujikawa, Miki Kou, Eiichi Hinoi, Yukio Yoneda
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69718 (2013)
We have shown the involvement of mitochondrial uncoupling protein-2 (UCP2) in the cytotoxicity by N-methyl-D-aspartate receptor (NMDAR) through a mechanism relevant to the increased mitochondrial Ca(2+) levels in HEK293 cells with acquired NMDAR chan
Externí odkaz:
https://doaj.org/article/6268f7a850be4126b42eaf3aaa3d23b5