Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ryosuke Shinozaki"'
Publikováno v:
Nutrients, Vol 14, Iss 14, p 2862 (2022)
Regulatory T cells (Tregs) and CD4+/CD25+ T cells play an important role in the suppression of excessive immune responses, homeostasis of immune function, and oral tolerance. In this study, we screened for food-derived polyphenols that induce Tregs i
Externí odkaz:
https://doaj.org/article/0eb0ebaa4c024585bc5dcd1088834986
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 94:3-P1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98882155de257cdd5fba77316bbc0500
https://doi.org/10.1254/jpssuppl.94.0_3-p1-28
https://doi.org/10.1254/jpssuppl.94.0_3-p1-28
Autor:
Akihiro Tai, Shigeyuki Uno, Ami Maehara, Hiroki Kakuta, Fuminori Ohsawa, Yutaka Yoshikawa, Hiroyuki Yasui, Kohei Kawata, Ryosuke Shinozaki, Yui Ohta, Makoto Makishima, Chisa Fujiwara, Toshitaka Oohashi, Manabu Hagaya, Masaru Nakayama, Nobumasa Yakushiji, Mariko Nakayama, Shoya Yamada
Publikováno v:
ACS Medicinal Chemistry Letters. 3:427-432
Treating insulin resistance and type 2 diabetes in rodents, currently known retinoid X receptor (RXR) agonists induce significant adverse effects. Here we introduce a novel RXR partial agonist CBt-PMN (11b), which shows a potent glucose-lowering effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbbd5aba52f28e9b9fb7206dc1d65885
https://doi.org/10.1021/ml300055n
https://doi.org/10.1021/ml300055n
Autor:
Akihiro Tai, Ryosuke Shinozaki, Makoto Makishima, Ryosuke Fukai, Shuji Fujii, Shuichi Enomoto, Shoya Yamada, Hiroki Kakuta, Fuminori Ohsawa
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:5139-5142
Retinoid X receptors (RXRs) function as homo- or heterodimers with other nuclear receptors, such as peroxisome proliferator-activated receptors (PPARs), which are targets for treatment of hyperlipidemia and type 2 diabetes, or liver X receptors (LXRs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d15d8f0132c04a2c7bdd13356fb199
https://doi.org/10.1016/j.bmcl.2010.07.012
https://doi.org/10.1016/j.bmcl.2010.07.012
Autor:
Kyohei Terao, Fumikazu Oohira, Yusaku Oka, Takaaki Suzuki, Fusao Shimokawa, Hidekuni Takao, Ryosuke Shinozaki
Publikováno v:
2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS).
In this study, a new assembly technique of separately fabricated MEMS optical devices on fragile MEMS actuator stages has been developed to realize novel functional optical-MEMS devices. This technique realizes the “assist-free” alignment and fix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dd3a7fbdd006e5a533e15bfb73ee73a
https://doi.org/10.1109/memsys.2014.6765669
https://doi.org/10.1109/memsys.2014.6765669
Autor:
Mariko Nakayama, Yuuki Furusawa, Kazutaka Kohara, Yui Ohta, Ryosuke Shinozaki, Shoya Yamada, Manabu Hagaya, Toshiki Kobayashi, Akihiro Tai, Chisa Fujiwara, Makoto Makishima, Hiroki Kakuta, Fuminori Ohsawa, Hiroyuki Yasui, Kohei Kawata, Hirotaka Naitou, Nobumasa Yakushiji, Yutaka Yoshikawa
Publikováno v:
Journal of medicinal chemistry. 56(5)
We have reported that retinoid X receptor (RXR) partial agonist 1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5-carboxylic acid (CBt-PMN, 4a) shows a significant antidiabetes effect in the KK-A(y) type 2 diabetes model mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f524744c51930841ddfd480c609d29
https://pubmed.ncbi.nlm.nih.gov/23391145
https://pubmed.ncbi.nlm.nih.gov/23391145
Autor:
Hiroki Kakuta, Fuminori Ohsawa, Ryosuke Shinozaki, Akihiro Tai, Shuji Fujii, Makoto Makishima, Shoya Yamada, Shuichi Enomoto, Hirotaka Naitou
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(17)
Retinoid X receptor (RXR) agonists are candidate agents for the treatment of metabolic syndrome and type 2 diabetes via activation of peroxisome proliferator-activated receptor (PPAR)/RXR or liver X receptor (LXR)/RXR-heterodimers, which control lipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e2973735d85f535ccb00784e909ec0
https://pubmed.ncbi.nlm.nih.gov/20667726
https://pubmed.ncbi.nlm.nih.gov/20667726
Publikováno v:
The Proceedings of Conference of Kanto Branch. :317-318
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f19254264b634fd9e5c705baa084bbc4
https://doi.org/10.1299/jsmekanto.2012.18.317
https://doi.org/10.1299/jsmekanto.2012.18.317
Autor:
Ryosuke Shinozaki, Kazunori Motoshima
Publikováno v:
YAKUGAKU ZASSHI. 131:315-316
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f424e02de2e403ef3e3c8413b13fcaed
https://doi.org/10.1248/yakushi.131.315
https://doi.org/10.1248/yakushi.131.315