Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Ryosuke Saigusa"'
Autor:
Joshua Slysz, Arjun Sinha, Matthew DeBerge, Shalini Singh, Harris Avgousti, Inhyeok Lee, Kristofor Glinton, Reina Nagasaka, Prarthana Dalal, Shaina Alexandria, Ching Man Wai, Ricardo Tellez, Mariavittoria Vescovo, Ashwin Sunderraj, Xinkun Wang, Matthew Schipma, Ryan Sisk, Rishab Gulati, Jenifer Vallejo, Ryosuke Saigusa, Donald M. Lloyd-Jones, Jon Lomasney, Samuel Weinberg, Karen Ho, Klaus Ley, Chiara Giannarelli, Edward B. Thorp, Matthew J. Feinstein
Publikováno v:
JCI Insight, Vol 8, Iss 17 (2023)
Femoral atherosclerotic plaques are less inflammatory than carotid plaques histologically, but limited cell-level data exist regarding comparative immune landscapes and polarization at these sites. We investigated intraplaque leukocyte phenotypes and
Externí odkaz:
https://doaj.org/article/a787c69545d94017b8a54872a8ab6581
Autor:
Shahad Iqneibi, Ryosuke Saigusa, Amir Khan, Mohammad Oliaeimotlagh, Sujit Silas Armstrong Suthahar, Sunil Kumar, Ahmad Alimadadi, Christopher P. Durant, Yanal Ghosheh, Coleen A. McNamara, Catherine C. Hedrick, Klaus Ley
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Coronary artery disease (CAD) is a major cause of death worldwide. The role of CD8+ T cells in CAD is unknown. Recent studies suggest a breakdown of tolerance in atherosclerosis, resulting in active T cell receptor (TCR) engagement with self-antigens
Externí odkaz:
https://doaj.org/article/06e37518823a4d04818e99cb80e328fc
Autor:
Jenifer Vallejo, Ryosuke Saigusa, Rishab Gulati, Sujit Silas Armstrong Suthahar, Vasantika Suryawanshi, Ahmad Alimadadi, Christopher P. Durant, Yanal Ghosheh, Payel Roy, Erik Ehinger, Tanyaporn Pattarabanjird, David B. Hanna, Alan L. Landay, Russell P. Tracy, Jason M. Lazar, Wendy J. Mack, Kathleen M. Weber, Adaora A. Adimora, Howard N. Hodis, Phyllis C. Tien, Igho Ofotokun, Sonya L. Heath, Avishai Shemesh, Coleen A. McNamara, Lewis L. Lanier, Catherine C. Hedrick, Robert C. Kaplan, Klaus Ley
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Cryopreserved peripheral blood mononuclear cells (PBMCs) are frequently collected and provide disease- and treatment-relevant data in clinical studies. Here, we developed combined protein (40 antibodies) and transcript single-cell
Externí odkaz:
https://doaj.org/article/02a45738c2a44c44b7e9d1b98a16d7b0
Autor:
Shunsuke Miura, Yusuke Watanabe, Ryosuke Saigusa, Takashi Yamashita, Kouki Nakamura, Megumi Hirabayashi, Takuya Miyagawa, Ayumi Yoshizaki, Maria Trojanowska, Shinichi Sato, Yoshihide Asano
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-9 (2021)
Abstract Background Aldehyde dehydrogenase 1 family member A1 (RALDH1)-producing dermal dendritic cells (DCs), a conventional DC subset regulating skin fibrosis, are decreased in the involved skin of patients with systemic sclerosis (SSc). In this st
Externí odkaz:
https://doaj.org/article/457a8ace5f7a4508829e85a184871dcc
Autor:
Tanyaporn Pattarabanjird, Jeffrey M. Wilson, Loren D. Erickson, Lisa J. Workman, Hui Qiao, Yanal Ghosheh, Rishab Gulati, Chistopher Durant, Jenifer Vallejo, Ryosuke Saigusa, Thomas A. E. Platts-Mills, Angela M. Taylor, Klaus Ley, Coleen A. McNamara
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Background: Recent studies have suggested that IgE sensitization to α-gal is associated with coronary artery disease (CAD). However, the B cell subtype(s) responsible for production of IgE to α-gal and mechanisms mediating this production remain el
Externí odkaz:
https://doaj.org/article/fdd20fd874ad4accbfddcc64261a926c
Autor:
Felix Sebastian Nettersheim, Simon Braumann, Kouji Kobiyama, Marco Orecchioni, Melanie Vassallo, Jacqueline Miller, Amal Ali, Payel Roy, Ryosuke Saigusa, Dennis Wolf, Klaus Ley, Holger Winkels
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Atherosclerosis is a chronic, lipid-driven disease of medium sized arteries which causes myocardial infarction and stroke. Recently, an adaptive immune response against the plaque-associated autoantigen Apolipoprotein B100 (ApoB), the structural prot
Externí odkaz:
https://doaj.org/article/f84e37816e4f40cd87007db8591f66d0
Autor:
Jenifer Vallejo, Ryosuke Saigusa, Rishab Gulati, Sujit Silas Armstrong Suthahar, Vasantika Suryawanshi, Ahmad Alimadadi, Christopher P. Durant, Yanal Ghosheh, Payel Roy, Erik Ehinger, Tanyaporn Pattarabanjird, David B. Hanna, Alan L. Landay, Russell P. Tracy, Jason M. Lazar, Wendy J. Mack, Kathleen M. Weber, Adaora A. Adimora, Howard N. Hodis, Phyllis C. Tien, Igho Ofotokun, Sonya L. Heath, Avishai Shemesh, Coleen A. McNamara, Lewis L. Lanier, Catherine C. Hedrick, Robert C. Kaplan, Klaus Ley
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/558c36d6bdf9422b83382750d816a780
Autor:
Kentaro Awaji, Takuya Miyagawa, Jun Omatsu, Hiroko Numajiri, Toru Kawai, Kaoru Funamizu, Ryosuke Saigusa, Daisuke Yamada, Yoshihide Asano, Shinichi Sato
Publikováno v:
Acta Dermato-Venereologica, Vol 101, Iss 8, p adv00527 (2021)
Systemic inflammatory response markers, including neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and monocyte-to-lymphocyte ratio, are useful prognostic factors for various malignant tumours. The aim of this study was to investigate the
Externí odkaz:
https://doaj.org/article/3197d48799b348f6ae029723c7c14904
Autor:
Ryosuke Saigusa, Yoshihide Asano, Takashi Taniguchi, Megumi Hirabayashi, Kouki Nakamura, Shunsuke Miura, Takashi Yamashita, Takehiro Takahashi, Yohei Ichimura, Tetsuo Toyama, Ayumi Yoshizaki, Maria Trojanowska, Shinichi Sato
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-11 (2018)
Abstract Background Friend leukemia virus integration 1 (Fli1) deficiency, a predisposing factor of systemic sclerosis (SSc), induces SSc-like phenotypes in various cell types. A recent study demonstrated the transdifferentiation of T helper type 2 c
Externí odkaz:
https://doaj.org/article/2affabc1493d4e9c9edce8ac5e0fb3eb
Autor:
Jun Omatsu, Ryosuke Saigusa, Takuya Miyagawa, Hiroko Numajiri, Kaname Akamata, Yuri Masui, Daisuke Yamada, Shinichi Sato
Publikováno v:
Acta Dermato-Venereologica, Vol 98, Iss 8, Pp 817-819 (2018)
Externí odkaz:
https://doaj.org/article/70dfc6f7f7fc41c3b6c11156578b0647