Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Ryosuke Nakashima"'
Autor:
Takuto Minami, Shin’ya Nakano, Vincent Lesur, Futoshi Takahashi, Masaki Matsushima, Hisayoshi Shimizu, Ryosuke Nakashima, Hinami Taniguchi, Hiroaki Toh
Publikováno v:
Earth, Planets and Space, Vol 72, Iss 1, Pp 1-24 (2020)
Abstract We have submitted a secular variation (SV) candidate model for the thirteenth generation of International Geomagnetic Reference Field model (IGRF-13) using a data assimilation scheme and a magnetohydrodynamic (MHD) dynamo simulation code. Th
Externí odkaz:
https://doaj.org/article/94fd0ff628304238a33454f1fecad5d1
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Multidrug efflux pumps are inner membrane transporters that export multiple antibiotics from the inside to the outside of bacterial cells, contributing to bacterial multidrug resistance (MDR). Postgenomic analysis has demonstrated that numerous multi
Externí odkaz:
https://doaj.org/article/b064dc085bba46ee95485b4c980c6ccb
Autor:
Martijn Zwama, Seiji Yamasaki, Ryosuke Nakashima, Keisuke Sakurai, Kunihiko Nishino, Akihito Yamaguchi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Multidrug transporters possess several drug binding sites. Here the authors describe a transport path specific for planar aromatic cations in the E. coli multi-drug transporter AcrB.
Externí odkaz:
https://doaj.org/article/cf87738eec424a5bb6b49a27e8fde79a
Autor:
Martijn Zwama, Katsuhiko Hayashi, Keisuke Sakurai, Ryosuke Nakashima, Kimie Kitagawa, Kunihiko Nishino, Akihito Yamaguchi
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
The overexpression of RND-type exporters is one of the main causes of multidrug resistance (MDR) in Gram-negative pathogens. In RND transporters, such as Escherichia coli's main efflux pump AcrB, drug efflux occurs in the porter domain, while protons
Externí odkaz:
https://doaj.org/article/b1ac10fa21bd4a1986eb55c987cd1699
Autor:
Masaaki Mori, Yoshiko Nakayama, Shigeo Nishimata, Tadafumi Yokoyama, Ryo Matsuoka, Reiko Hatori, Masaki Shimizu, Katsuhiro Arai, Yuri Etani, Tsuyoshi Sogo, Tomoko Ishizu, Masahiro Nii, Ryosuke Nakashima, Toshiaki Shimizu
Publikováno v:
Pediatric Gastroenterology, Hepatology & Nutrition; Sep2024, Vol. 27 Issue 5, p274-285, 12p
Autor:
Keisuke Shinohara, Shota Ikeda, Soichiro Kashihara, Sho Matsumoto, Daisuke Yoshida, Ryosuke Nakashima, Yoshiyasu Ono, Hiroyuki Tsutsui
Publikováno v:
Physiology. 38
Introduction: Paraventricular nucleus of hypothalamus (PVN), a control center of sympathetic outflow, receives the input from afferent renal nerves. Although acute stimulation of afferent renal nerves increases central sympathetic outflow, it remains
Autor:
Daisuke Yoshida, Keisuke Shinohara, Soichiro Kashihara, Shota Ikeda, Sho Matsumoto, Ryosuke Nakashima, Yoshiyasu Ono, Hiroyuki Tsutsui
Publikováno v:
Physiology. 38
Background: Women appear to have a better prognosis of heart failure compared to men. Estrogen, a major sex hormone, can cross the blood-brain barrier, and the signaling through estrogen receptor in the brain may have a sympathoinhibitory effect. Sym
Publikováno v:
Journal of Cardiovascular Electrophysiology. 33:1592-1595
We report a 28-year-old female patient with congenital type 2 long QT syndrome (LQTS) in which mexiletine shortened corrected QT interval (QTc) and effectively prevented refractory Torsade de Pointes (TdP) and ventricular fibrillation (VF). She devel
Autor:
Seiji Yamasaki, Naoki Koga, Martijn Zwama, Keisuke Sakurai, Ryosuke Nakashima, Akihito Yamaguchi, Kunihiko Nishino
Publikováno v:
Antimicrobial agents and chemotherapy. 66(11)
The multidrug efflux transporters MexB and MexY in Pseudomonas aeruginosa and AcrB in Escherichia coli contribute to these organisms' multidrug resistance. Efflux pump inhibitor (EPI) ABI-PP inhibits MexB and AcrB, but not MexY. We previously determi
Autor:
Shota Ikeda, Keisuke Shinohara, Soichiro Kashihara, Sho Matsumoto, Daisuke Yoshida, Ryosuke Nakashima, Yoshiyasu Ono, Masaaki Nishihara, Kenichi Katsurada, Hiroyuki Tsutsui
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 46(1)
The activation of sympathetic nervous system plays a critical role in the development of hypertension. The input from afferent renal nerves may affect central sympathetic outflow; however, its contribution to the development of hypertension remains u