Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ryosuke NAKA"'
Autor:
Ryosuke Naka, Yoshimitsu Shimomura, Madoka Kanda‐Kato, Nobuhiro Hiramoto, Shigeo Hara, Takayuki Ishikawa
Publikováno v:
eJHaem, Vol 4, Iss 3, Pp 829-832 (2023)
Abstract Monoclonal gammopathy of undetermined significance (MGUS) is a benign but precancerous condition that can progress to multiple myeloma. Patients with MGUS are typically monitored closely for signs of disease progression, but in some cases, t
Externí odkaz:
https://doaj.org/article/ba43d3cdc90b456587d9570a6610a79c
Publikováno v:
FEBS Open Bio, Vol 13, Iss 4, Pp 684-700 (2023)
Proper regulation of apoptotic cell death is crucial for normal development and homeostasis in multicellular organisms and is achieved by the balance between pro‐apoptotic processes, such as caspase activation, and pro‐survival signaling, such as
Externí odkaz:
https://doaj.org/article/e394731198434bdebf29ea74634de0d5
Autor:
Ryosuke Naka, Tadakazu Kondo, Masashi Nishikubo, Hiroyuki Muranushi, Yasunori Ueda, Tomomi Oka, Fumiya Wada, Junya Kanda, Shohei Yamamoto, Mitsumasa Watanabe, Shinri Okada, Kazunori Imada, Yukiharu Nakabo, Yu Mizutani, Yasuhito Nannya, Seishi Ogawa, Takayuki Ishikawa
Publikováno v:
HemaSphere, Vol 7, p e8463360 (2023)
Externí odkaz:
https://doaj.org/article/27af9106d0ff440db83f6c969b03091f
Autor:
Yuji Kubota, Yuko Fujioka, Ashwini Patil, Yusuke Takagi, Daisuke Matsubara, Masatomi Iijima, Isao Momose, Ryosuke Naka, Kenta Nakai, Nobuo N. Noda, Mutsuhiro Takekawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
MEK1 mutations are found in cancer and RASopathies, but their effects remain unclear. Here, the authors reveal a mutant MEK1 structure and qualitative differences in biological properties between the cancer- and RASopathy-associated mutants, providin
Externí odkaz:
https://doaj.org/article/9947a9cf2139440e875defedf512d313
Autor:
Ryosuke Naka, Hitomi Kaneko, Osamu Nagata, Kohei Tada, Masaharu Tashima, Chisato Mizutani, Kazunori Imada
Publikováno v:
eJHaem, Vol 3, Iss 2, Pp 513-516 (2022)
Abstract When immune thrombocytopenia (ITP) is secondary to malignant diseases, chemotherapy is expected to improve the platelet count (PC) as well. Herein, we report a case of a 72‐year‐old man with ITP refractory to standard therapies. IgM mono
Externí odkaz:
https://doaj.org/article/d0d1c9b8e7c9498e99c0d409405a27b8
Autor:
Jun-ichi KODAMA, Takuto TATEKAWA, Ryosuke NAKA, Akihiro HAMANAKA, Ken-ichi ITAKURA, Gota DEGUCHI, Daisuke FUKUDA, Yoshiaki FUJII
Publikováno v:
Journal of MMIJ, Vol 134, Iss 7, Pp 91-98 (2018)
Small-scale underground coal gasification (UCG) model tests with a linking hole were carried out using two types of specimens made of either block coal or crushed coal to clarify their characteristics of combustion and gasification. Many similar char
Externí odkaz:
https://doaj.org/article/acc9e5a26afd486f9feb1ed70424ceba
Autor:
Pavlina Chuntova, Kira Downey, Ryusuke Hatae, Tiffany A Chen, Abigail L Mende, Megan Montoya, Bjoern Schwer, Jayne Skinner, Hideho Okada, Gary Kohanbash, Takahide Nejo, Yitzhar E. Goretsky, Yafei Hou, Hong-Erh Liang, David Diebold, Akane Yamamichi, Ryosuke Naka
Publikováno v:
Neuro-oncology, vol 24, iss 2
Neuro Oncol
Neuro Oncol
Background Rigorous preclinical studies of chimeric antigen receptor (CAR) immunotherapy will require large quantities of consistent and high-quality CAR-transduced T (CART) cells that can be used in syngeneic mouse glioblastoma (GBM) models. To this
Autor:
Ryosuke Naka, Kohei Tada, Hitomi Kaneko, Osamu Nagata, Masaharu Tashima, Chisato Mizutani, Kazunori Imada
Publikováno v:
Leukemialymphoma. 63(6)
Autor:
Yuji Kubota, Yuko Fujioka, Ashwini Patil, Yusuke Takagi, Daisuke Matsubara, Masatomi Iijima, Isao Momose, Ryosuke Naka, Kenta Nakai, Nobuo N. Noda, Mutsuhiro Takekawa
Publikováno v:
Nature communications. 13(1)
Point-mutations of MEK1, a central component of ERK signaling, are present in cancer and RASopathies, but their precise biological effects remain obscure. Here, we report a mutant MEK1 structure that uncovers the mechanisms underlying abnormal activi
Autor:
Tiffany A Chen, David Diebold, Yitzhar E. Goretsky, Hideho Okada, Bjoern Schwer, Yafei Hou, Jayne Skinner, Hong-Erh Liang, Abigail L Mende, Ryosuke Naka, Pavlina Chuntova, Kira Downey, Megan Montoya, Gary Kohanbash, Takahide Nejo, Akane Yamamichi
BackgroundRigorous preclinical studies of chimeric antigen receptor (CAR) immunotherapy will require large quantities of consistent and high-quality CAR-transduced T (CART)-cells that can be used in syngeneic mouse glioblastoma (GBM) models. To this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b86bcff4afeb945f4ecee99fa7142dc
https://doi.org/10.1101/2021.01.31.429020
https://doi.org/10.1101/2021.01.31.429020