Výsledky vyhledávání - "Ryosuke Miyatake"

Does hypofrontality expand to global brain area in progression of schizophrenia?: A cross-sectional study between first-episode and chronic schizophrenia

Autor: Hideaki Hayashi, Toshihiko Ohkami, Yoshitaka Uchida, Goro Fukami, Takuya Asaka, Takayuki Shibuya, Tsuyoshi Sasaki, Tasuku Hashimoto, Hiroyuki Watanabe, Eiji Shimizu, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayama, Nobuhisa Kanahara, Yoshimoto Sekine, Hiroshi Yamanaka, Makoto Asano, Ryosuke Miyatake, Mihisa Fujisaki

Publikováno v: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 33:410-415

Although to date there have been no conclusive pathophysiological findings in support of the degenerative theory of the etiology of schizophrenia, the results of neuroimaging studies have suggested that progressive changes in the brain do occur durin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050eeeed14609363f229ccbe0f88fb73
https://doi.org/10.1016/j.pnpbp.2008.12.017

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Association study between thePIK4CAgene and methamphetamine use disorder in a Japanese population

Autor: Tokutaro Komiyama, Nobuhisa Kanahara, Hiroshi Ujike, Ryosuke Miyatake, Kenji Hashimoto, Norio Ozaki, Mitsuhiko Yamada, Ichiro Sora, Mutsuo Harano, Nakao Iwata, Toshiya Inada, Yoshimoto Sekine, Masaomi Iyo

Publikováno v: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :233-238

Accumulating evidence suggests that phosphatidylinositol (PI) pathways have been involved in the secretion of dopamine (DA) and the regulation of DA transporter, which is a target of methamphetamine (METH). A recent large-scale gene-association study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c05a5bd6cd538b94e6e0843f51c37ea
https://doi.org/10.1002/ajmg.b.30797

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Identification of Functional Polymorphisms in the Promoter Region of the Human PICK1 Gene and Their Association With Methamphetamine Psychosis

Publikováno v: American Journal of Psychiatry. 164:1105-1114

Protein interacting with C-kinase-1 (PICK1) plays a role in the targeting and clustering of dopamine transporter, which is the primary target site for the abused drug methamphetamine. Based on the interaction of PICK1 with dopamine transporter, it is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33bea3f023388adad20d88719509d00
https://doi.org/10.1176/ajp.2007.164.7.1105

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Lack of association between sigma1 receptor gene variants and schizophrenia

Autor: Fumiaki Satoh, Ryosuke Miyatake, Hiroshi Suwaki, Aizo Furukawa

Publikováno v: Psychiatry and Clinical Neurosciences. 58:359-363

Several pharmacological studies suggest the possible involvement of sigma(1) receptors in the pathogenesis of schizophrenia. An association has been reported between schizophrenia and two variants (GC-241-240TT and Gln2Pro) in the sigma(1) receptor g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e1d0ede63d029444195190630a553ea
https://doi.org/10.1111/j.1440-1819.2004.01268.x

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Functional polymorphisms in the sigma1 receptor gene associated with alcoholism

Autor: Susumu Higuchi, Aizo Furukawa, Sachio Matsushita, Hiroshi Suwaki, Ryosuke Miyatake

Publikováno v: Biological Psychiatry. 55:85-90

Sigma1 receptors are involved in the pathogenesis of drug abuse. Two polymorphisms (GC-241-240TT and Gln2Pro) in the sigma1 receptor gene (SIGMAR1) have been identified. To investigate the role of SIGMAR1 in conveying susceptibility to alcoholism, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c67add62b35a3fbe7114fab1298f73
https://doi.org/10.1016/j.biopsych.2003.07.008

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Identification of a novel variant of the human NR2B gene promoter region and its possible association with schizophrenia

Autor: Ryosuke Miyatake, A. Furukawa, Hiroshi Suwaki

Publikováno v: Molecular Psychiatry. 7:1101-1106

N-methyl-D-aspartate (NMDA) receptor dysfunction is involved in the pathogenesis of schizophrenia. We determined the nucleotide sequence of the 5'-upstream region of the human NMDA receptor 2B (NR2B) subunit gene and identified a novel T-200G variant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862c1c5cf27bb34b17a49e91dfbde47f
https://doi.org/10.1038/sj.mp.4001152

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Haloperidol Inhibits Neuronal Nitric Oxide Synthase Activity by Preventing Electron Transfer

Autor: Ryosuke Miyatake, Kiyoshi Hosokawa, Hiroshi Suwaki, Hirohito Yoneyama, Taira Ohnishi, Yoshiyuki Ichikawa, Kazuhiko Iwahashi, Kazuhiko Nakamura

Publikováno v: Neuropsychobiology. 33:76-79

The effect of a neuroleptic, haloperidol (HP), on nitric oxide formation catalyzed by neuronal nitric oxide synthase (n-NOS) in the porcine brain was investigated. HP inhibited n-NOS activity noncompetitively versus L-arginine as a substrate, decreas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842cebbc024a28e904c2ed2daeb06e31
https://doi.org/10.1159/000119253

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Association study between polymorphisms in glutathione-related genes and methamphetamine use disorder in a Japanese population

Autor: Norio Ozaki, Nakao Iwata, Daisuke Matsuzawa, Toshiya Inada, Kenji Hashimoto, Tokutaro Komiyama, Ryosuke Miyatake, Mitsuhiko Yamada, Tasuku Hashimoto, Ichiro Sora, Mutsuo Harano, Yoshimoto Sekine, Hiroshi Ujike, Masaomi Iyo

Publikováno v: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. (7)

Accumulating evidence suggests that oxidative stress plays a role in the mechanisms of action of methamphetamine (METH) in the brain. In the present study, we investigated the association between the genetic polymorphisms among glutathione (GSH)-rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e419ed54fd73884e5f59468aa6caa2
https://pubmed.ncbi.nlm.nih.gov/18186040

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Combined intoxication with methylone and 5-MeO-MIPT

Autor: Eiji Shimizu, Masaomi Iyo, Hiroyuki Watanabe, Kenji Hashimoto, Takashi Kojima, Hiroko Hagiwara, Mihisa Fujisaki, Ryosuke Miyatake

Publikováno v: Progress in neuro-psychopharmacologybiological psychiatry. 31(1)

Although preclinical studies suggest that methylone (2-methylamino-1-[3,4-methylenedioxyphenyl]propan-1-one) and 5-MeO-MIPT (5-methoxy-N-methyl,N-isopropyl tryptamine) may have psychostimulant properties, the scientific reports about the clinical eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dcf5629cffdb06ee44e1592cebe3d3b
https://pubmed.ncbi.nlm.nih.gov/16876302

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