Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ryosuke Makita"'
Autor:
Aya Sugiyama, Toshihiko Matsuoka, Kazuaki Sakamune, Tomoyuki Akita, Ryosuke Makita, Shinsuke Kimura, Yukio Kuroiwa, Masataka Nagao, Junko Tanaka
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234967 (2020)
ObjectivesThe Tokyo subway sarin attack in 1995 was an unprecedented act of terrorism that killed 13 people and sickened more than 6,000. The long-term somatic and psychological effects on its victims remain unknown.MethodsWe conducted analyses on th
Externí odkaz:
https://doaj.org/article/4ac7f4afacf64b7eb7681befcddd9e0f
Autor:
Masataka Nagao, Akira Namera, Aiko Torikoshi, Masao Yoshizumi, Takeo Itoh, Hiroaki Shiraishi, Ryosuke Makita, Yosuke Arima, Yoshimasa Watanabe, Yoshitaka Maeno
Publikováno v:
Toxicology and Applied Pharmacology. 272:61-66
The organophosphorus compound sarin irreversibly inhibits acetylcholinesterase. We examined the acute cardiovascular effects of a sarin-like organophosphorus agent, bis(isopropyl methyl)phosphonate (BIMP), in anaesthetized, artificially ventilated ra
Autor:
Hiroaki Shiraishi, Kazunori Imaizumi, Ryosuke Makita, Masataka Nagao, Kazuhiro Murata, Atsushi Saito, Akira Namera, Yosuke Arima, Kanji Yoshimoto
Publikováno v:
The Journal of toxicological sciences. 41(5)
Organophosphorus (OP) compounds such as sarin are toxic agents that irreversibly inhibit the enzyme acetylcholinesterase. A recent study showed that OP compounds also have multiple toxicity mechanisms, and another suggested that endoplasmic reticulum
Autor:
Yosuke, Arima, Kanji, Yoshimoto, Akira, Namera, Ryosuke, Makita, Kazuhiro, Murata, Masataka, Nagao
Publikováno v:
Hiroshima journal of medical sciences. 65(1)
Organophosphorus compounds, such as sarin, are highly toxic nerve agents that inhibit acetylcholinesterase (AChE), but not cholinesterase, via multiple mechanisms. Recent studies have shown that organophosphorus compounds increase cyclooxygenase-2 (C
Autor:
Osamu Nakagawa, Peter Igarashi, Patricia Cobo-Stark, Hiroki Kurihara, Qin Chen, Tomokazu Amano, Yukiko Kurihara, Masao Murakami, Yasunobu Uchijima, Koichi Nishiyama, Ryosuke Makita, Yutaka Yatomi, Hiroyuki Aburatani, Junji Tominaga, Takahiro Sato, Akihisa Mitani, Takahide Nagase, Erin V. Small, Takumi Takeuchi, Tomoichiro Asano
Publikováno v:
American Journal of Physiology-Renal Physiology. 294:F542-F553
TAZ (transcriptional coactivator with PDZ-binding motif), also called WWTR1 (WW domain containing transcription regulator 1), is a 14-3-3-binding molecule homologous to Yes-associated protein. TAZ acts as a coactivator for several transcription facto
Autor:
Junji Tominaga, Yukiko Kurihara, Yasunobu Uchijima, Osamu Nakagawa, Hiroki Kurihara, Ryosuke Makita, Tomoichiro Asano, Masao Murakami
Publikováno v:
Biochemical and Biophysical Research Communications. 339:533-539
Pax3 is a transcription factor which functions in embryonic development and human diseases. In a yeast two-hybrid screen with full-length Pax3 as bait, we isolated a clone encoding transcriptional co-activator with PDZ-binding motif (TAZ) from an E10
Autor:
Tetsuji Tomita, Ryosuke Makita, Shigetomo Fukuhara, Yasuhiro Yamaguchi, Takahide Nagase, Yasuyoshi Ouchi, Takashi Tominaga, Hiroki Kurihara
Publikováno v:
The Journal of Immunology. 169:2516-2523
Defensins comprise a family of cationic antimicrobial peptides that are characterized by the presence of six conserved cysteine residues. We identified two novel human β-defensin (hBD) isoforms by mining the public human genomic sequences. The predi
Autor:
Chieh J. Chou, Akihiro Yamanaka, Chu-Xia Deng, Masahisa Yamada, Tsuyoshi Miyakawa, Jacqueline N. Crawley, Christian C. Felder, Ryosuke Makita, Toru Moriguchi, Jürgen Wess, Alokesh Duttaroy, Masaharu Ogawa, Bing Xia
Publikováno v:
Nature. 410:207-212
Members of the muscarinic acetylcholine receptor family (M1-M5) have central roles in the regulation of many fundamental physiological functions. Identifying the specific receptor subtype(s) that mediate the diverse muscarinic actions of acetylcholin
Publikováno v:
Mechanisms of Development. 71(1-2):165-176
This study analyzed the spatial and temporal expression pattern of zebrafish wnt11 and the regulation of the expression during zebrafish early development, focusing on the interaction with the no tail (ntl) gene, a zebrafish orthologue of mouse Brach
Publikováno v:
Development, Growth and Differentiation. 37:605-616
Genetic transduction of newt was undertaken in search of conditions allowing high exogenous gene expression in stages from late embryo to larva when regeneration experiments, which are advantageous for this group of animals, are possible. DNA of a β