Zobrazeno 1 - 10
of 1 208
pro vyhledávání: '"Ryosuke, TAKAHASHI"'
Publikováno v:
JSES Reviews, Reports, and Techniques, Vol 4, Iss 4, Pp 774-778 (2024)
Background: This study aimed to evaluate the efficacy of pre-emptive middle glenohumeral ligament (MGHL) release during arthroscopic rotator cuff repair (ARCR) of small- to medium-sized tears to prevent postoperative stiffness. Methods: Patients who
Externí odkaz:
https://doaj.org/article/732e0be727b047a4976a6dfe797d1741
Autor:
Tomonori Hoshino, Atsushi Mukai, Hirofumi Yamashita, Hidemi Misawa, Makoto Urushitani, Yoshitaka Tashiro, Shu-ichi Matsuzawa, Ryosuke Takahashi
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-4 (2024)
Abstract Protein turnover is crucial for cell survival, and the impairment of proteostasis leads to cell death. Aging is associated with a decline in proteostasis, as the progressive accumulation of damaged proteins is a hallmark of age-related disor
Externí odkaz:
https://doaj.org/article/bfb7ac35605849319db0cacb21ff7e5e
Autor:
Noritoshi Sekido, Fujio Matsuyama, Tatsunori Murata, Ryosuke Takahashi, Mihoko Matsuoka, Atsushi Sengoku, Masashi Nomi, Takeya Kitta, Takahiko Mitsui
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract While preventing renal damage and symptomatic urinary tract infection are of paramount importance to persons with a spinal cord lesion (SCL), patient-reported outcomes (PROs) are receiving much more attention than ever before. We performed a
Externí odkaz:
https://doaj.org/article/d05c0110a5a14d10a8139839b87547c5
Autor:
Masahiro Mitsuhashi, Reona Yamaguchi, Toshinari Kawasaki, Satoko Ueno, Yiping Sun, Kaoru Isa, Jun Takahashi, Kenta Kobayashi, Hirotaka Onoe, Ryosuke Takahashi, Tadashi Isa
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Whether and how the non-lesional sensorimotor cortex is activated and contributes to post-injury motor recovery is controversial. Here, we investigated the role of interhemispheric pathway from the contralesional to ipsilesional premotor cor
Externí odkaz:
https://doaj.org/article/1b6bcb85086648e28ecb0b681dfcc717
Autor:
Misako Minote, Wakiro Sato, Kimitoshi Kimura, Atsuko Kimura, Youwei Lin, Tomoko Okamoto, Ryosuke Takahashi, Takashi Yamamura
Publikováno v:
Immunological Medicine, Vol 47, Iss 3, Pp 151-165 (2024)
‘No evidence of disease activity (NEDA)’, judged by clinical and radiological findings, is a therapeutic goal in patients with multiple sclerosis (MS). It is, however, unclear if distinct biological mechanisms contribute to the maintenance of NED
Externí odkaz:
https://doaj.org/article/2818c12adf8f4488bdfb5691502b7be2
Autor:
Masanori Sawamura, Kiyoshi Tachikawa, Rie Hikawa, Hisako Akiyama, Seiji Kaji, Ken Yasuda, Angel I. Leu, Hyojung Hong, Rajesh Mukthavaram, Pad Chivukula, Hodaka Yamakado, Yoshio Hirabayashi, Ryosuke Takahashi, Shu-ichi Matsuzawa
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102380- (2024)
Despite the wide range of applications of mRNA therapies, major difficulties exist in the efficient delivery of mRNA into oligodendrocytes, a type of glial cell in the brain. Commonly used viral vectors are not efficient in transforming oligodendrocy
Externí odkaz:
https://doaj.org/article/a690f55095224122b98cf44013d30ce2
Autor:
Gen Sobue, Hirofumi Maruyama, Keiko Imamura, Yuishin Izumi, Satoshi Morita, Naohiro Egawa, Takashi Ayaki, Makiko Nagai, Kazutoshi Nishiyama, Yasuhiro Watanabe, Ritsuko Hanajima, Koji Fujita, Naoto Takahashi, Akiko Morinaga, Ryosuke Takahashi, Haruhisa Inoue, Naoki Atsuta, Osamu Kano, Takehisa Hirayama, Takao Kiriyama, Hiroshi Kataoka, Takahiko Tokuda, Kazuma Sugie, Takenobu Murakami, Hitoki Nanaura, Masahiro Nakamori, Shotaro Haji, Harutsugu Tatebe, Riko Tabuchi, Motoki Oe, Mihoko Kobayashi, Kasia Lobello
Publikováno v:
BMJ Open, Vol 14, Iss 10 (2024)
Introduction Amyotrophic lateral sclerosis (ALS) is a progressive, severe neurodegenerative disease caused by motor neuron death. Development of a medicine for ALS is urgently needed, and induced pluripotent cell-based drug repurposing identified a S
Externí odkaz:
https://doaj.org/article/63d3495d00e24d60a205cd5377da8720
Autor:
Tomoyuki Ishimoto, Miki Oono, Seiji Kaji, Takashi Ayaki, Katsuya Nishida, Itaru Funakawa, Takakuni Maki, Shu-ichi Matsuzawa, Ryosuke Takahashi, Hodaka Yamakado
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract The aggregated alpha-synuclein (αsyn) in oligodendrocytes (OLGs) is one of the pathological hallmarks in multiple system atrophy (MSA). We have previously reported that αsyn accumulates not only in neurons but also in OLGs long after the a
Externí odkaz:
https://doaj.org/article/cd30b625e77b48f48134f51505938d29
Autor:
Hidefumi Suzuki, Naohiro Egawa, Keiko Imamura, Takayuki Kondo, Takako Enami, Kayoko Tsukita, Mika Suga, Yuichiro Yada, Ran Shibukawa, Ryosuke Takahashi, Haruhisa Inoue
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Synucleinopathies refer to a group of disorders characterized by SNCA/α-synuclein (α-Syn)-containing cytoplasmic inclusions and neuronal cell loss in the nervous system including the cortex, a common feature being cognitive impairment. Sti
Externí odkaz:
https://doaj.org/article/e2c171af79924b389b070d5267a36739
Publikováno v:
JSES Reviews, Reports, and Techniques, Vol 4, Iss 1, Pp 113-117 (2024)
Externí odkaz:
https://doaj.org/article/722a6c9d441f4ee588bc9cc3fa341517