Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ryosuke, Fujikane"'
Autor:
Aya Fujikane, Ryosuke Fujikane, Sumiko Hyuga, Yusuke Sechi, Tetsuya Hiyoshi, Atsuhiko Sakamoto, Akinori Nishi, Hiroshi Odaguchi, Kenji Hiromatsu, Yukihiro Goda, Yoshizumi Ishino, Shigeki Nabeshima
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Respiratory syncytial virus (RSV) is a major cause of respiratory tract infection in children. Despite decades of efforts, no effective therapies are available. We recently reported that extracts of Ephedra Herb and Cinnamon Bark interacted with the
Externí odkaz:
https://doaj.org/article/c5350b1f1ca74a75bb4106c87ccb9f06
Autor:
Aya Fujikane, Atsuhiko Sakamoto, Ryosuke Fujikane, Akinori Nishi, Yoshizumi Ishino, Kenji Hiromatsu, Shigeki Nabeshima
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Two components within the traditional herbal medicine maoto can bind to the G protein of the respiratory syncytial virus, blocking the virus from entering mammalian cells.
Externí odkaz:
https://doaj.org/article/6cb6ea8a1982459d8ba2072cd147e726
Autor:
Ryosuke Fujikane, Isabelle Behm-Ansmant, Anne-Sophie Tillault, Christine Loegler, Valérie Igel-Bourguignon, Evelyne Marguet, Patrick Forterre, Christiane Branlant, Yuri Motorin, Bruno Charpentier
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Archaeal RNA:pseudouridine-synthase (PUS) Cbf5 in complex with proteins L7Ae, Nop10 and Gar1, and guide box H/ACA sRNAs forms ribonucleoprotein (RNP) catalysts that insure the conversion of uridines into pseudouridines (Ψs) in ribosomal RNA
Externí odkaz:
https://doaj.org/article/8f4e286c4b614fb4bbbba9971d936c88
Publikováno v:
Genes to Cells. 25:175-186
O6 -Methylguanines (O6 -meG), which are produced in DNA by the action of alkylating agents, are mutagenic and cytotoxic, and induce apoptosis in a mismatch repair (MMR) protein-dependent manner. To understand the molecular mechanism of O6 -meG-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54d98b289410b420ecf26b9d84190343
https://doi.org/10.1111/gtc.12748
https://doi.org/10.1111/gtc.12748
Autor:
Arato Takedachi, Erina Matsuishi, Shouji Mizusaki, Tomoki Nagasawa, Ryosuke Fujikane, Masumi Hidaka, Shigenori Iwai, Isao Kuraoka
Publikováno v:
Mutation research. 824
Mismatch repair (MMR) is a highly conserved DNA repair pathway that corrects mismatched bases during DNA replication. The biological significance of MMR in human cells is underscored by the fact that dysfunction of the MMR pathway results in Lynch sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02abd9dedefd9aab741c88ba18539311
https://pubmed.ncbi.nlm.nih.gov/35472567
https://pubmed.ncbi.nlm.nih.gov/35472567
Autor:
Aya Fujikane, Ryosuke Fujikane, Shigeki Nabeshima, Kenji Hiromatsu, Yoshizumi Ishino, Akinori Nishi, Atsuhiko Sakamoto
Although respiratory syncytial virus (RSV) is a major cause of respiratory tract infection in children, no effective therapies are available. Recently, RSV G, the attachment glycoprotein, has become a major focus in the development of therapeutic str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb3e9e87142e9fa707d6a48770a77477
https://doi.org/10.21203/rs.3.rs-262616/v1
https://doi.org/10.21203/rs.3.rs-262616/v1
Autor:
Mihoko, Rikitake, Ryosuke, Fujikane, Yuko, Obayashi, Kyoko, Oka, Masao, Ozaki, Masumi, Hidaka
Publikováno v:
Genes to cells : devoted to molecularcellular mechanismsREFERENCES. 25(3)
O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aabe8324226700026e9caca992e7883a
https://pubmed.ncbi.nlm.nih.gov/31955481
https://pubmed.ncbi.nlm.nih.gov/31955481
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44817 (2012)
O⁶-Methylguanine, one of alkylated DNA bases, is especially mutagenic. Cells containing this lesion are eliminated by induction of apoptosis, associated with the function of mismatch repair (MMR) proteins. A retrovirus-mediated gene-trap mutagenesi
Externí odkaz:
https://doaj.org/article/32041a432ac944a8bde15029a1900493
Autor:
Akiyoshi Shimamoto, Maki Nakamura, Soichi Takiguchi, Yoshimichi Nakatsu, Shinya Oda, Yingxia Song, Ryosuke Fujikane, Namiko Hayashi, Masumi Hidaka, Seijiro Shioi, Ayumi Take, Kyoko Hidaka
Publikováno v:
DNA Repair. 108:103216
In prokaryotes and yeasts, DNA polymerase proofreading (PPR) and DNA mismatch repair (MMR) cooperatively counteracts replication errors leading to repeat sequence destabilization (i.e. insertions/deletions of repeat units). However, PPR has not thus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7a0a9c2186553e6145f15de5b89286
https://doi.org/10.1016/j.dnarep.2021.103216
https://doi.org/10.1016/j.dnarep.2021.103216
Autor:
Ryosuke Fujikane, Masumi Hidaka, Mihoko Rikitake, Mutsuo Sekiguchi, Yuko Obayashi, Yukimasa Takeishi
Publikováno v:
J Biol Chem
The mismatch repair (MMR) complex is composed of MutSα (MSH2-MSH6) and MutLα (MLH1-PMS2) and specifically recognizes mismatched bases during DNA replication. O6-Methylguanine is produced by treatment with alkylating agents, such as N-methyl-N-nitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b141fad4604ef05211120cd37a1e7550
https://pubmed.ncbi.nlm.nih.gov/31843968
https://pubmed.ncbi.nlm.nih.gov/31843968