Leucine and protein metabolism in obese Zucker rats.

Autor: Pengxiang She, Kristine C Olson, Yoshihiro Kadota, Ayami Inukai, Yoshiharu Shimomura, Charles L Hoppel, Sean H Adams, Yasuko Kawamata, Hideki Matsumoto, Ryosei Sakai, Charles H Lang, Christopher J Lynch

Publikováno v: PLoS ONE, Vol 8, Iss 3, p e59443 (2013)

Branched-chain amino acids (BCAAs) are circulating nutrient signals for protein accretion, however, they increase in obesity and elevations appear to be prognostic of diabetes. To understand the mechanisms whereby obesity affects BCAAs and protein me

Externí odkaz: https://doaj.org/article/bc7491a2b576400fbe7fe655b6dde271

Glutamate metabolism in a human intestinal epithelial cell layer model

Autor: Yasuko Kawamata, Tomoko Shimada, Asuka Takumi, Yuri Ooba, Hidehiro Nakamura, Akiko Watanabe, Takahiro Narita, Johannes B. van Goudoever, Ryosei Sakai

Publikováno v: Sakai, R, Ooba, Y, Watanabe, A, Nakamura, H, Kawamata, Y, Shimada, T, Takumi, A, van Goudoever, J B & Narita, T 2020, ' Glutamate metabolism in a human intestinal epithelial cell layer model ', Amino Acids, vol. 52, no. 11-12, pp. 1505-1519 . https://doi.org/10.1007/s00726-020-02908-2
Amino Acids, 52(11-12), 1505-1519. Springer Wien

Plasma glutamate concentrations are constant despite dynamic changes in diets. Most likely, virtually all the dietary glutamate is metabolized in the gut. The present study investigated permeability and metabolism of dietary glutamate in a Caco-2 int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6814f945d1dccfa58c148e61d883ad
http://www.scopus.com/inward/record.url?scp=85095883808&partnerID=8YFLogxK

Dispensable Amino Acids, except Glutamine and Proline, Are Ideal Nitrogen Sources for Protein Synthesis in the Presence of Adequate Indispensable Amino Acids in Adult Men

Autor: Ryosei Sakai, Ronald O. Ball, Paul B. Pencharz, Leah Cooper, Rajavel Elango

Publikováno v: The Journal of nutrition. 150(9)

Nutritionally, there is a dietary requirement for indispensable amino acids (IAAs) but also a requirement for nitrogen (N) intake for the de novo synthesis of the dispensable amino acids (DAAs). It has been suggested that there might be a dietary req

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820d69eedaae963f21bb7bee1dececa5
https://pubmed.ncbi.nlm.nih.gov/32879983

Thirteen week toxicity study of dietary l -tryptophan in rats with a recovery period of 5 weeks

Autor: Tsutomu Fukuwatari, Takumi Ohishi, Ryosei Sakai, Hideki Matsumoto, Yoko Masuzawa, Yusuke Shibui, Katsumi Shibata

Publikováno v: Journal of Applied Toxicology. 38:552-563

Although l-tryptophan is nutritionally important and widely used in medical applications, toxicity data for its oral administration are limited. The purpose of this study was to evaluate the potential toxicity of an experimental diet containing added

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::791ae0ad56521d0cda0d56d4455c7f1b
https://doi.org/10.1002/jat.3562

Gastric Emptying of Elemental Liquid Diets Versus Semisolid Diets in Bedridden Gastrostomy-fed Patients

Autor: Ryosei Sakai, Masashi Kajiyama, Naoki Tanaka, Akio Morikawa, Akira Horiuchi, Michio Tamaki

Publikováno v: Journal of clinical gastroenterology. 53(5)

BACKGROUND Aspiration is a common problem in bedridden gastrostomy-fed patients. We compared gastric emptying of an elemental liquid diet and a commercial semisolid diet in bedridden gastrostomy-fed patients. METHODS Study 1: from January 2013 to Dec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c022613214966c4702409da2a66eaa58
https://pubmed.ncbi.nlm.nih.gov/29570173