Výsledky vyhledávání - "Ryosaku Sakamoto"

Developing dissolution testing methodologies for extended-release oral dosage forms with supersaturating properties. Case example: Solid dispersion matrix of indomethacin

Autor: Yukihiro Ozaki, Tomokazu Tajiri, Satoshi Kitamura, Christos Reppas, Shigeaki Morita, Hisahi Mimura, Ryosaku Sakamoto

Publikováno v: International Journal of Pharmaceutics. 490:368-374

The objective of this study was to develop an in vitro dissolution test method with discrimination ability for an extended-release solid dispersion matrix of a lipophilic drug using the United States Pharmacopeia (USP) Apparatus 4, flow-through cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4035afb9bbe99d3b66fcf690a039bccc
https://doi.org/10.1016/j.ijpharm.2015.05.054

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3D manipulation of single cells using dielectrophoretic probe array

Autor: Takayuki Shibata, Moeto Nagai, Ryosaku Sakamoto, Takuro Saeki

Publikováno v: MHS

Three dimensional (3D) single cell manipulation plays a critical role in the development of cell engineering. Cell manipulation techniques are potentially applied to reconstruct in vitro modeled cells. Our aim is to develop a dielectrophoretic (DEP)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d93dd93476b8ae6413e5d16a9c2fa045
https://doi.org/10.1109/mhs.2016.7824214

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Separation selectivity of aqueous polyethylene glycol-based separation systems: DSC, LC and aqueous two-phase extraction studies

Autor: Takayuki Baba, Ryosaku Sakamoto, Shingo Saito, Masami Shibukawa, Koichi Oguma, Ryoichi Ichikawa

Publikováno v: Polymer. 49:4168-4173

The distribution behavior of n-alcohols, ketones and nitroalkanes in aqueous liquid chromatography with a column packed with polyethylene glycol (PEG) gel, TSKgel Ether-250, was compared with that in aqueous two-phase systems (ATPSs) formed from PEG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b8431bd10a729515409dd92c547435
https://doi.org/10.1016/j.polymer.2008.07.042

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Development and characterization of dielectrophoretic probe array for non-invasive massively parallel manipulation of single cells

Autor: Moeto Nagai, Ryosaku Sakamoto, Yuya Matsuse, Takayuki Shibata

Publikováno v: MHS

Cell manipulation system is an essential tool for reconstruction of cellular microenvironment that leads to high-throughput function analysis. Our aim is the development of dielectrophoretic probe array for non-invasive and massively parallel manipul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b95b731b911a6bd20e1879e04275409
https://doi.org/10.1109/mhs.2015.7438340

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Liquid chromatography and differential scanning calorimetry studies on the states of water in hydrophilic polymer gel packings in relation to retention selectivity

Autor: Ryosaku Sakamoto, Masami Shibukawa, Kaoru Aoyagi, Koichi Oguma

Publikováno v: Journal of Chromatography A. 832:17-27

The amounts of water which exhibit selectivity to solutes in water-swollen hydrophilic polymer gel packings were determined by a liquid chromatographic method designed on the basis of the mobile phase electrolyte effects on the retention of ionic sol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45da9078e1da687dea4febae81df8f20
https://doi.org/10.1016/s0021-9673(98)00988-1

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Release mechanisms of acetaminophen from polyethylene oxide/polyethylene glycol matrix tablets utilizing magnetic resonance imaging

Autor: Satoshi Kitamura, Masazumi Suzuki, Yukihiro Ozaki, Shigeaki Morita, Ryosaku Sakamoto, Tomokazu Tajiri, Shigeyuki Yamanashi

Publikováno v: International journal of pharmaceutics. 395(1-2)

Release mechanism of acetaminophen (AAP) from extended-release tablets of hydrogel polymer matrices containing polyethylene oxide (PEO) and polyethylene glycol (PEG) were achieved using flow-through cell with magnetic resonance imaging (MRI). The hyd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d368ed20aed1d5bda84ad7766d26ba
https://pubmed.ncbi.nlm.nih.gov/20580795

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Solute retention and the states of water in polyethylene glycol and poly(vinyl alcohol) gels

Autor: Takayuki Baba, Masami Shibukawa, Koichi Oguma, Ryosaku Sakamoto

Publikováno v: Journal of chromatography. A. 1040(1)

[Abstract] The states of water sorbed in a cross-linked polyethylene glycol (PEG) gel, TSKgel Ether-250, and cross-linked poly(vinyl alcohol) (PVA) gels of different pore sizes, TSKgel Toyopearl HW-40S, 50S, 55S and 75S, were investigated by means of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c47cae2455dcc31ecd7d9a5b9881db
https://pubmed.ncbi.nlm.nih.gov/15248424

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