Non-coding RNA suppresses FUS aggregation caused by mechanistic shear stress on pipetting in a sequence-dependent manner

Autor: Nesreen Hamad, Ryoma Yoneda, Masatomo So, Riki Kurokawa, Takashi Nagata, Masato Katahira

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Abstract Fused in sarcoma/translocated in liposarcoma (FUS/TLS) is a multitasking RNA/DNA binding protein. FUS aggregation is implicated in various neurodegenerative diseases. RNA was suggested to modulate phase transition of FUS. Here, we found that

Externí odkaz: https://doaj.org/article/b7b2712f3e574bf6929132ce72be59a8

Long noncoding RNA pncRNA-D reduces cyclin D1 gene expression and arrests cell cycle through RNA m6A modification

Autor: Riki Kurokawa, Naomi Ueda, Kousuke Uranishi, Masataka Hirasaki, Ryoma Yoneda

Publikováno v: Journal of Biological Chemistry. 295:5626-5639

pncRNA-D is an irradiation-induced 602-nt long noncoding RNA transcribed from the promoter region of the cyclin D1 (CCND1) gene. CCND1 expression is predicted to be inhibited through an interplay between pncRNA-D and RNA-binding protein TLS/FUS. Beca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9d5546fad061ee99f24adfd01263189
https://doi.org/10.1074/jbc.ra119.011556

m6A Modified Short RNA Fragments Inhibit Cytoplasmic TLS/FUS Aggregation Induced by Hyperosmotic Stress

Autor: Ryoma Yoneda, Riki Kurokawa, Naomi Ueda

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 20
International Journal of Molecular Sciences, Vol 22, Iss 11014, p 11014 (2021)

Translocated in LipoSarcoma/Fused in Sarcoma (TLS/FUS) is a nuclear RNA binding protein whose mutations cause amyotrophic lateral sclerosis. TLS/FUS undergoes LLPS and forms membraneless particles with other proteins and nucleic acids. Interaction wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8df4b4ffade719abe935147de3f1de

Crystallographic and optical properties of wide bandgap photovoltaic semiconductor system, Cu(Al,In)Se 2

Autor: Ryoma Yoneda, Kosuke Beppu, Tsuyoshi Maeda, Takahiro Wada

Publikováno v: Japanese Journal of Applied Physics. 61:SC1080

We characterized the optical and electronic properties of chalcopyrite-type Cu(Al,In)Se2, which is a candidate for wide-bandgap solar cell materials. The bandgap energy was determined from diffuse reflectance spectra. The bandgap energy increased fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8013b328bf1fcc00afb2170210845109
https://doi.org/10.35848/1347-4065/ac48cf

Long noncoding RNA

Autor: Ryoma, Yoneda, Naomi, Ueda, Kousuke, Uranishi, Masataka, Hirasaki, Riki, Kurokawa

Publikováno v: J Biol Chem

pncRNA-D is an irradiation-induced 602-nt long noncoding RNA transcribed from the promoter region of the cyclin D1 (CCND1) gene. CCND1 expression is predicted to be inhibited through an interplay between pncRNA-D and RNA-binding protein TLS/FUS. Beca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ff852a5cb72ba9c9a0b0fa2637ddec81
https://pubmed.ncbi.nlm.nih.gov/32165496