Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ryoko Uemoto"'
Autor:
Tomoyo Hara, Ryoko Uemoto, Akiko Sekine, Yukari Mitsui, Shiho Masuda, Kiyoe Kurahashi, Sumiko Yoshida, Toshiki Otoda, Tomoyuki Yuasa, Akio Kuroda, Yasumasa Ikeda, Itsuro Endo, Soichi Honda, Katsuhiko Yoshimoto, Akira Kondo, Toshiaki Tamaki, Toshio Matsumoto, Munehide Matsuhisa, Masahiro Abe, Ken‐ichi Aihara
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 12, Pp 2172-2182 (2021)
Abstract Aims/Introduction Thrombin exerts various pathophysiological functions by activating protease‐activated receptors (PARs). Recent data have shown that PARs influence the development of glomerular diseases including diabetic kidney disease (
Externí odkaz:
https://doaj.org/article/994aad1d67334b8989c29528c6f31641
Autor:
Shiho Masuda, Toshio Matsumoto, Toshiki Otoda, Ryoko Uemoto, Akiko Sekine, Soichi Honda, Sumiko Yoshida, Akira Kondo, Munehide Matsuhisa, Akio Kuroda, Toshiaki Tamaki, Tomoyo Hara, Ken-ichi Aihara, Tomoyuki Yuasa, Yasumasa Ikeda, Masahiro Abe, Kiyoe Kurahashi, Itsuro Endo, Yukari Mitsui, Katsuhiko Yoshimoto
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 12, Pp 2172-2182 (2021)
Journal of Diabetes Investigation
Journal of Diabetes Investigation
Aims/Introduction Thrombin exerts various pathophysiological functions by activating protease‐activated receptors (PARs). Recent data have shown that PARs influence the development of glomerular diseases including diabetic kidney disease (DKD) by r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49f18135c3ed880879b918fba3ed84f
https://doi.org/10.1111/jdi.13602
https://doi.org/10.1111/jdi.13602
Autor:
Tomoyo Hara, Ryoko Uemoto, Akiko Sekine, Yukari Mitsui, Shiho Masuda, Hiroki Yamagami, Kiyoe Kurahashi, Sumiko Yoshida, Toshiki Otoda, Tomoyuki Yuasa, Akio Kuroda, Yasumasa Ikeda, Itsuro Endo, Soichi Honda, Katsuhiko Yoshimoto, Akira Kondo, Toshiaki Tamaki, Toshio Matsumoto, Munehide Matsuhisa, Masahiro Abe, Ken-ichi Aihara
Publikováno v:
Journal of Atherosclerosis and Thrombosis.
Thrombin exerts various pathophysiological functions by activating protease-activated receptors (PARs), and thrombin-induced activation of PARs promotes the development of non-alcoholic fatty liver disease (NAFLD). Since heparin cofactor II (HCII) sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8af514378a542487866d7a95e5fb073
https://doi.org/10.5551/jat.63752
https://doi.org/10.5551/jat.63752
Autor:
Ken-ichi Aihara, Ryoko Uemoto, Takeshi Mitsuhashi, Sumiko Yoshida, Shusuke Yagi, Kazue Ishikawa, Toshio Matsumoto, Masashi Akaike, Yasumasa Ikeda
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aim: Statins have a protective impact against cardiovascular diseases through not only lipid-lowering effects but also pleiotropic effects, including activation of the endothelial nitric oxide synthase (eNOS) system. We aimed to clarify the protectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31db1b4bce1c37bf96d716ed86f89d76
https://doi.org/10.5551/jat.37747
https://doi.org/10.5551/jat.37747
Autor:
Kazue Ishikawa, Masato Miyake, Toshio Matsumoto, Sumiko Yoshida, Ryoko Uemoto, Seika Inoue, Hiroshi Sakaue, Masahiro Abe, Kiyoe Kurahashi, Takeshi Kondo, Yasumasa Ikeda, Tomoyuki Yuasa, Seiichi Oyadomari, Kana Morimoto, Ken-ichi Aihara, Itsuro Endo
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aim: Accelerated thrombin action is associated with insulin resistance. It is known that upon activation by binding to dermatan sulfate proteoglycans, heparin cofactor II (HCII) inactivates thrombin in tissues. Because HCII may be involved in glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d901399ed9539c6d272aa70bf0b86cab
http://europepmc.org/articles/PMC5742367
http://europepmc.org/articles/PMC5742367
Autor:
Kazue Ishikawa, Toshio Matsumoto, Yuka Sumitomo-Ueda, Ryoko Uemoto, Takayuki Ise, Matomo Sakari, Ken-ichi Takeyama, Shigeaki Kato, Masataka Sata, Takashi Iwase, Shusuke Yagi, Yasumasa Ikeda, Sumiko Yoshida, Takahiro Matsumoto, Kenneth Walsh, Masashi Akaike, Mitsuru Matsumoto, Ken-ichi Aihara, Yasuhiro Mouri
Publikováno v:
Circulation. 128:60-71
Background— Hypoandrogenemia is associated with an increased risk of ischemic diseases. Because actions of androgens are exerted through androgen receptor (AR) activation, we studied hind-limb ischemia in AR knockout mice to elucidate the role of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c5177f49ca085cb27e281f739c3e4c
https://doi.org/10.1161/circulationaha.113.001533
https://doi.org/10.1161/circulationaha.113.001533
Autor:
Hirotsugu Yamada, Sumiko Yoshida, Susumu Nishio, Hiromi Kawano, Masashi Akaike, Yuka Sumitomo-Ueda, Yasumasa Ikeda, Ken-ichi Aihara, Masataka Sata, Yoichiro Hirata, Junko Miki, Hiroyuki Azuma, Toshio Matsumoto, Takashi Iwase, Shusuke Yagi, Ryoko Uemoto
Publikováno v:
Atherosclerosis. 212:310-315
Background Dehydroepiandrosterone sulfate (DHEAS) is thought to be associated with life expectancy and anti-aging. However, its biological significance in atherosclerosis remains controversial. Therefore, the aim of this study was to determine whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3057633f74f61bbba82da95d3bfb263d
https://doi.org/10.1016/j.atherosclerosis.2010.05.011
https://doi.org/10.1016/j.atherosclerosis.2010.05.011
Autor:
Yuka Sumitomo-Ueda, Takayuki Ise, Shusuke Yagi, Sumiko Yoshida, Yoichiro Hirata, Masashi Akaike, Kazue Ishikawa, Ryoko Uemoto, Takashi Iwase, Toshio Matsumoto, Ken-ichi Aihara, Yasumasa Ikeda, Masataka Sata, Shigeaki Kato
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 56(3)
Heparin cofactor II (HCII), a serine protease inhibitor, inhibits tissue thrombin action after binding with dermatan sulfate proteoglycans in the extracellular matrix of the vascular system. We previously reported that heterozygous HCII-deficient (HC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d197b011380d722390667f88452e36
https://pubmed.ncbi.nlm.nih.gov/20660821
https://pubmed.ncbi.nlm.nih.gov/20660821
Autor:
Sumiko Yoshida, Ken-ichi Aihara, Yasumasa Ikeda, Yuka Sumitomo-Ueda, Ryoko Uemoto, Kazue Ishikawa, Takayuki Ise, Shusuke Yagi, Takashi Iwase, Yasuhiro Mouri, Matomo Sakari, Takahiro Matsumoto, Ken-ichi Takeyama, Masashi Akaike, Mitsuru Matsumoto, Masataka Sata, Kenneth Walsh, Shigeaki Kato, Toshio Matsumoto
Publikováno v:
Circulation; 7/2/2013, Vol. 128 Issue 1, p60-71, 12p