Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ryoko Sawahata"'
Autor:
Masahiro Azuma, Ryoko Sawahata, Yuusuke Akao, Takashi Ebihara, Sayuri Yamazaki, Misako Matsumoto, Masahito Hashimoto, Koichi Fukase, Yukari Fujimoto, Tsukasa Seya
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12489 (2010)
Natural killer (NK) cells are lymphocyte effectors that are activated to control certain microbial infections and tumors. Many NK-activating and regulating receptors are involved in regulating NK cell function. In addition, activation of naïve NK ce
Externí odkaz:
https://doaj.org/article/6e66933f5aaa4c6cae433dffe199fc72
Autor:
Mitsuru Sato1, Ryoko Sawahata1, Chisato Sakuma1, Takato Takenouchi1, Hiroshi Kitani1 kitani@affrc.go.jp
Publikováno v:
Scientific Reports. 10/25/2013, p1-10. 10p.
Autor:
Joe Chiba, Hiroshi Kitani, Mitsuru Sato, Ryo Iwaya, Ryoko Sawahata, Kenji Sekikawa, Yoshikazu Kurosawa, Kazumasa Ogihara
Publikováno v:
FEBS Journal. 272:6131-6144
Intracellularly expressed antibodies (intrabodies) have been used to inhibit the function of various kinds of protein inside cells. However, problems with stability and functional expression of intrabodies in the cytosol remain unsolved. In this stud
Autor:
Hadia Mohammad Abdelaal Mohammad, Shengbin Li, Ryoko Sawahata, Gwantwa Mwakalundwa, Kathryn Fraser, Geetha Mylvaganam, Mauricio Martins, David Masopust, Rama Rao Amara, David Watkins, Elizabeth Connick, Pamela J Skinner
Publikováno v:
The Journal of Immunology. 198:225.19-225.19
There is a need to develop an effective HIV vaccine. We earlier showed that during chronic HIV-1/SIV infections, HIV/SIV replication is concentrated within B cell follicles, whereas HIV/SIV-specific CD8 T cells are largely excluded from these sites s
Publikováno v:
Scientific Reports
Intrabody technology provides a novel approach to decipher the molecular mechanisms of protein function in cells. Single domains composed of only the variable regions (V(H) or V(L)) of antibodies are the smallest recombinant antibody fragments to be
Publikováno v:
International immunology. 23(8)
Wiskott-Aldrich syndrome protein (WASP) plays important roles in TCR signaling. In transgenic (Tg) mice, over-expression of the WASP N-terminal region (exons 1-5) including the enabled/vasodilator-stimulated phosphoprotein (Ena/VASP) homology 1 (EVH1
Autor:
Takashi Akazawa, Hiroaki Shime, Koichi Fukase, Norimitsu Inoue, Yukari Fujimoto, Ryoko Sawahata, Misako Matsumoto, Tsukasa Seya, Sayuri Yamazaki
Publikováno v:
Microbes and infection. 13(4)
Macrophage-activating lipopeptide 2 (MALP-2), a mycoplasmal diacylated lipopeptide with palmitic acid moiety (Pam2), activates Toll-like receptor (TLR) 2 to induce inflammatory cytokines. TLR2 is known to mature myeloid dendritic cells (mDC) to drive
Publikováno v:
Experimental and molecular pathology. 86(1)
Intracellularly expressed antibody fragments (intrabodies) have been utilized as powerful tools not only for clinical applications but also for the functional analysis of proteins inside the cell. Among several types of intrabodies developed so far,
Publikováno v:
International immunology. 19(8)
Wiskott-Aldrich syndrome protein (WASP) plays important roles in TCR signaling, but its roles in signal transduction in innate immune cells have not been well characterized. As microglia are the primary immune effector cells in the brain, WASP may po
Autor:
Mitsuru, Sato, Ryo, Iwaya, Kazumasa, Ogihara, Ryoko, Sawahata, Hiroshi, Kitani, Joe, Chiba, Yoshikazu, Kurosawa, Kenji, Sekikawa
Publikováno v:
The FEBS journal. 272(23)
Intracellularly expressed antibodies (intrabodies) have been used to inhibit the function of various kinds of protein inside cells. However, problems with stability and functional expression of intrabodies in the cytosol remain unsolved. In this stud