Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ryoko Kuniyoshi"'
Autor:
Tomoko Takayama, Yasuhito Terui, Keisho Chin, Mariko Mikuniya, Nobuyuki Mizunuma, Satoshi Matsusaka, Sayuri Minowa, Kiyohiko Hatake, Yuji Mishima, Mariko Ogura, Harumi Shibata, Ryoko Kuniyoshi
Publikováno v:
Targeted oncology. 12(3)
A key to the successful use of targeted cancer therapy is the ability to preselect patients who are likely to benefit from the treatment according to molecular markers. Assessment for predicting therapy response is mostly done using tumor biopsies. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a541ed1dec2cd653b8eece7634c8d1c0
https://pubmed.ncbi.nlm.nih.gov/28508152
https://pubmed.ncbi.nlm.nih.gov/28508152
Autor:
Ryoko Kuniyoshi, Mitsukuni Suenaga, Nobuyuki Mizunuma, Yuji Mishima, Yasuhito Terui, Satoshi Matsusaka, Kiyohiko Hatake
Publikováno v:
Cancer. 117:4026-4032
BACKGROUND: Bevacizumab plus chemotherapy is a standard option in the treatment of metastatic colorectal cancer (mCRC). The aim of this study was to investigate the potential of circulating endothelial cell progenitors (CEPs) and phenotypical circula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab1dd120a54faa24d37c773b560aa37
https://doi.org/10.1002/cncr.25977
https://doi.org/10.1002/cncr.25977
Autor:
Kengo Takeuchi, Yuji Mishima, Yuko Mishima, Chie Watanabe, Yasuhito Terui, Kiyotsugu Kojima, Yoshinori Ito, Akiko Taniyama, Sakura Sakajiri, Takuma Sakurai, Ryoko Kuniyoshi, Kiyohiko Hatake, Shunji Takahashi, Masahiro Yokoyama, Natsuhiko Sugimura
Publikováno v:
Clinical Cancer Research. 15:2523-2530
Purpose: Rituximab is commonly incorporated into CD20-positive B-cell lymphoma therapy to improve response and prognosis. With increasing use, resistance to rituximab is a continuing concern, but CD20 mutation as a cause of resistance has not previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700a11120c64b15ec514646b1021a391
https://doi.org/10.1158/1078-0432.ccr-08-1403
https://doi.org/10.1158/1078-0432.ccr-08-1403
Autor:
Kiyohiko Hatake, Tadashi Kasahara, Yoshiko Sonoda, Eriko Aizu-Yokota, Ryoko Kuniyoshi, Yuko Mishima, Yasuhito Terui, Akiko Rokudai, Yuji Mishima
Publikováno v:
Biological and Pharmaceutical Bulletin. 29:1102-1109
Allergic asthma and allergic dermatitis are chronic inflammatory diseases and are characterized by an accumulation of eosinophils at sites of inflammation. Eotaxin-1/CCL11 and eotaxin-3/CCL26 are members of the CC chemokine family, which are known to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72563697aa6ad12b76b658ab75887d22
https://doi.org/10.1248/bpb.29.1102
https://doi.org/10.1248/bpb.29.1102
Autor:
Yasuhito Terui, Satoshi Matsusaka, Yuji Mishima, Ryoko Kuniyoshi, Kiyohiko Hatake, Yuko Mishima, Kiyotsugu Kojima, Mariko Mikuniya
Publikováno v:
International immunology. 24(8)
The anti-CD20 chimeric monoclonal antibody rituximab mediates cytotoxicity in malignant B cells via multiple mechanisms, including complement-dependent cytotoxicity (CDC), antibody-dependent cellular cytotoxicity (ADCC) and direct induction of apopto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c8f04ca1bd91f4c92665f67b6ff1e3
https://pubmed.ncbi.nlm.nih.gov/22438420
https://pubmed.ncbi.nlm.nih.gov/22438420
Autor:
Kiyohiko Hatake, Mitsukuni Suenaga, Yuji Mishima, Nobuyuki Mizunuma, Ryoko Kuniyoshi, Yasuhito Terui, Satoshi Matsusaka, Koichi Takagi
Publikováno v:
Cancer science. 102(6)
The purpose of this study was to investigate the potential of circulating tumor cells (CTC) as a surrogate marker of the clinical outcome in metastatic colorectal cancer (mCRC) patients in order to identify Japanese patients responsive to oxaliplatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ad3add335a4231d0e4518af492d409
https://pubmed.ncbi.nlm.nih.gov/21401804
https://pubmed.ncbi.nlm.nih.gov/21401804
Publikováno v:
SUMO Regulation of Cellular Processes ISBN: 9789048126507
Apoptosis is a physiological mechanism to maintain human tissues or cells, and pathological dysfunction of this process explains some disease states or drug resistance. P53, mdm2, sumoylation, signal transduction, and transcriptional control are impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ded43303a2f1a5a0cafd0bf726f903e
https://doi.org/10.1007/978-90-481-2649-1_13
https://doi.org/10.1007/978-90-481-2649-1_13
Autor:
Akiko Taniyama, Ryoko Kuniyoshi, Kiyohiko Hatake, Yasuhito Terui, Keiya Ozawa, Toshihiro Takizawa, Shinya Kimura, Yuko Mishima, Yuji Mishima
Publikováno v:
Cancer science. 99(11)
Autophagy, a cellular degradation system has been demonstrated in some hematopoietic malignant cell lines, but there is much still remaining to be known about its role and the mechanisms. We observed the excessive autophagy in chronic myelogenous leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d9ff882d1de0eb7b5ff9e3e906e1fa
https://pubmed.ncbi.nlm.nih.gov/18823378
https://pubmed.ncbi.nlm.nih.gov/18823378
Autor:
Yuko Matsumoto-Mishima, Yasuhito Terui, Kiyohiko Hatake, Natsuhiko Sugimura, Akiko Rokudai, Ryoko Kuniyoshi, Yuji Mishima
Publikováno v:
Cancer science. 98(3)
CD13/aminopeptidase-N (CD13/APN) is an important regulator of angiogenesis where its expression on activated blood vessels is induced by angiogenic signals. A previous study demonstrated that angiogenesis is suppressed under the presence of high conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7a6ad94f4324148bab8b44e47fc7d5
https://pubmed.ncbi.nlm.nih.gov/17270026
https://pubmed.ncbi.nlm.nih.gov/17270026
Publikováno v:
Molecular Cancer Therapeutics. 8:B68-B68
Background: Resistance to imatinib mesylate is a major problem in chronic myeloid leukaemia (CML) treatment. Most of the studies about the resistance have focused on point mutations in BCR/ABL. However, other mechanisms of resistance that do not impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c648df2c359344c6c4d16e4f8647cbab
https://doi.org/10.1158/1535-7163.targ-09-b68
https://doi.org/10.1158/1535-7163.targ-09-b68