An internally modulated, thermostable, pH-sensitive Cys loop receptor from the hydrothermal vent worm Alvinella pompejana

Autor: Reinhold Horlacher, Wolfram Welte, Fabrice Marger, Daniel Bertrand, Puneet Juneja, Ryoko Krause

Publikováno v: The Journal of biological chemistry. 289(21)

Cys loop receptors (CLRs) are commonly known as ligand-gated channels that transiently open upon binding of neurotransmitters to modify the membrane potential. However, a class of cation-selective bacterial homologues of CLRs have been found to open

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eded08e557a121e5c7c69386de50dd96
https://pubmed.ncbi.nlm.nih.gov/24719323

An evaluation of emerging vaccines for childhood pneumococcal pneumonia

Autor: Troy Jacobs, Shabir A. Madhi, Ang Choon Seong, Igor Rudan, Craig E. Rubens, Shams El Arifeen, Harry Campbell, Tanvir M. Huda, Jian Shayne F Zhang, Lina Zgaga, Hope L. Johnson, Ryoko Krause, Abdullah Brooks, Harish Nair, Evropi Theodoratou, Julia Webster

Publikováno v: Webster, J, Theodoratou, E, Nair, H, Seong, A C, Zgaga, L, Huda, T, Johnson, H L, Madhi, S, Rubens, C, Zhang, J S F, El Arifeen, S, Krause, R, Jacobs, T A, Brooks, A W, Campbell, H & Rudan, I 2011, ' An evaluation of emerging vaccines for childhood pneumococcal pneumonia ', BMC Public Health, vol. 11 Suppl 3, pp. S26 . https://doi.org/10.1186/1471-2458-11-S3-S26
BMC Public Health
BMC Public Health, Vol 11, Iss Suppl 3, p S26 (2011)

Background Pneumonia is the leading cause of child mortality worldwide. Streptococcus pneumoniae (SP) or pneumococcus is estimated to cause 821,000 child deaths each year. It has over 90 serotypes, of which 7 to 13 serotypes are included in current f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cef0664d5bf803a5b62477cff4e3c03
https://www.pure.ed.ac.uk/ws/files/8122076/An_evaluation_of_emerging_vaccines_for_childhood_pneumococcal_pneumonia.pdf

Unexpected sensitivity of the human alpha7 neuronal nicotinic acetylcholine receptor to aminoglycosides

Autor: Sonia Bertrand, Jean-Charles Hoda, Ryoko Krause, Daniel Bertrand

Publikováno v: Neuroreport. 17(1)

The wide use of antibiotics and the development of resistance is a major health concern and, despite their relatively severe side effects, aminoglycoside antibiotics are still used in clinics. Effects of seven aminoglycosides were investigated at the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8cb7d24e1b804a73ee14b22eea2d389
https://pubmed.ncbi.nlm.nih.gov/16361952

A voltage-dependent proton current in cultured human skeletal muscle myotubes

Autor: Charles R. Bader, Laurent Bernheim, Martine Hamann, Ryoko Krause, André Kaelin, Anne Baroffio

Publikováno v: The Journal of Physiology, Vol. 470 (1993) pp. 313-333

1. A voltage-dependent proton current, IH, was studied in cultured myotubes obtained from biopsies of human muscle, using whole-cell recording with the patch-clamp technique. 2. With a pHo of 8.0 and a calculated pHi of 6.3, IH was activated at volta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b731eb8240a6728ee959a8d8f9aa87cc
https://pubmed.ncbi.nlm.nih.gov/7508503

Human skeletal muscle has a voltage-gated proton current

Autor: Ryoko Krause, Laurent Bernheim, Charles R. Bader

Publikováno v: Neuromuscular Disorders, Vol. 3, No 5-6 (1993) pp. 407-411

A voltage-gated proton current, IH, was studied with the whole-cell patch-clamp technique in human myotubes obtained from biopsies of human muscle. Studies of the reversal potential of IH during substitution of K+, Na+, Ca2+, Cl-, Cs+, and H+ in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4315e0ead3af65f6e759bd81d2765a9
https://archive-ouverte.unige.ch/unige:10085