Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Ryoko, Araki"'
Autor:
Ryoko Araki, Tomo Suga, Yuko Hoki, Kaori Imadome, Misato Sunayama, Satoshi Kamimura, Mayumi Fujita, Masumi Abe
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Genomic aberrations are a critical impediment for the safe medical use of iPSCs and their origin and developmental mechanisms remain unknown. Here we find through WGS analysis of human and mouse iPSC lines that genomic mutations are de novo
Externí odkaz:
https://doaj.org/article/c9a67a6a7e1842b9b98236430276c28b
Autor:
Katsuhisa Omagari, Juna Ishida, Konomi Murata, Ryoko Araki, Mizuki Yogo, Bungo Shirouchi, Kazuhito Suruga, Nobuko Sera, Kazunori Koba, Mayuko Ichimura-Shimizu, Koichi Tsuneyama
Publikováno v:
Livers, Vol 4, Iss 2, Pp 193-208 (2024)
Oxidative stress and inflammation play a central role in the progression of nonalcoholic steatohepatitis (NASH), which can lead to liver cirrhosis. Barley bran has potential bioactivities due to its high content of functional substances, such as anth
Externí odkaz:
https://doaj.org/article/47d2ddc695cd4b21863df56d9ebe1ce0
Autor:
Ryoko Araki, Yuko Hoki, Tomo Suga, Chizuka Obara, Misato Sunayama, Kaori Imadome, Mayumi Fujita, Satoshi Kamimura, Miki Nakamura, Sayaka Wakayama, Andras Nagy, Teruhiko Wakayama, Masumi Abe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Point mutations have been found in induced pluripotent stem cells (iPSCs) but when they arise is unclear. Here, the authors show that a G1/S cell cycle checkpoint deficiency transiently occurs early in genome reprogramming, suggesting a common develo
Externí odkaz:
https://doaj.org/article/fead58306cee46a28867f75c35cbe41b
Publikováno v:
Hydrological Sciences Journal. :1-18
Autor:
Kunle Odunsi, Takaaki Oba, Hans Minderman, Kenichi Makino, Ryutaro Kajihara, Toshihiro Yokoi, Ryoko Araki, Masumi Abe, Alfred E Chang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Dendritic cells (DCs) are a promising therapeutic target in cancer immunotherapy given their ability to prime antigen-specific T cells, and initiate antitumor immune response. A major obstacle for DC-based immunotherapy is the difficulty t
Externí odkaz:
https://doaj.org/article/b0b53910545d499abfe3d46f4a5b5925
Autor:
Daniel Joyce, Masayuki Fujino, Miwa Morita, Ryoko Araki, John Fung, Shiguang Qian, Lina Lu, Xiao-Kang Li
Publikováno v:
Stem Cell Research, Vol 29, Iss , Pp 32-41 (2018)
Myeloid-derived suppressor cells (MDSCs) are markedly increased in cancer patients and tumor-bearing mice and promote tumor growth and survival by inhibiting host innate and adaptive immunity. In this study, we generated and characterized MDSCs from
Externí odkaz:
https://doaj.org/article/1b2c4f9052de43bf95ee41bf74d7a10a
Autor:
Masahito Yoshihara, Ryoko Araki, Yasuji Kasama, Misato Sunayama, Masumi Abe, Kohji Nishida, Hideya Kawaji, Yoshihide Hayashizaki, Yasuhiro Murakawa
Publikováno v:
Cell Reports, Vol 21, Iss 2, Pp 308-315 (2017)
Summary: Induced pluripotent stem cells (iPSCs) are generated by direct reprogramming of somatic cells and hold great promise for novel therapies. However, several studies have reported genetic variations in iPSC genomes. Here, we investigated point
Externí odkaz:
https://doaj.org/article/fdc5f976fc674c8289aa6a7624f8ebd0
Autor:
Songjie Cai, Jiangang Hou, Masayuki Fujino, Qi Zhang, Naotsugu Ichimaru, Shiro Takahara, Ryoko Araki, Lina Lu, Ji-Mei Chen, Jian Zhuang, Ping Zhu, Xiao-Kang Li
Publikováno v:
Stem Cell Reports, Vol 8, Iss 5, Pp 1174-1189 (2017)
Regulatory dendritic cell (DCregs)-based immunotherapy is a potential therapeutic tool for transplant rejection. We generated DCregs from murine induced pluripotent stem cells (iPSCs), which could remain in a “stable immature stage” even under st
Externí odkaz:
https://doaj.org/article/44d8091af2fe45cca19dcbc1e61bf910
Autor:
Yasushi Uemura, Kiyotaka Kuzushima, Yasuharu Nishimura, Yoshiaki Sonoda, Yasushi Sakamoto, Yoshiki Akatsuka, Masumi Abe, Ryoko Araki, Hayao Nakanishi, Shinobu Tsuzuki, Yutaka Sasaki, Yoshikazu Matsuoka, Ryusuke Nakatsuka, Hiroyuki Maki, Norihiro Ueda, Minako Tatsumi, Motoharu Suzuki, Narumi Hirosawa, Miwa Haruta, Satoru Senju, Tian-Yi Liu, Rong Zhang
Protection against subcutaneously inoculated OVA-expressing melanoma by OVA-peptide loaded iPS-pMC-DCs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbcfc9eb85fbee825f2c07dd7262550
https://doi.org/10.1158/2326-6066.22538446.v1
https://doi.org/10.1158/2326-6066.22538446.v1
Autor:
Yasushi Uemura, Kiyotaka Kuzushima, Yasuharu Nishimura, Yoshiaki Sonoda, Yasushi Sakamoto, Yoshiki Akatsuka, Masumi Abe, Ryoko Araki, Hayao Nakanishi, Shinobu Tsuzuki, Yutaka Sasaki, Yoshikazu Matsuoka, Ryusuke Nakatsuka, Hiroyuki Maki, Norihiro Ueda, Minako Tatsumi, Motoharu Suzuki, Narumi Hirosawa, Miwa Haruta, Satoru Senju, Tian-Yi Liu, Rong Zhang
The use of dendritic cells (DC) to prime tumor-associated antigen-specific T-cell responses provides a promising approach to cancer immunotherapy. Embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC) can differentiate into functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7053bfac658f0397d0c50596ef37cc78
https://doi.org/10.1158/2326-6066.c.6548785.v1
https://doi.org/10.1158/2326-6066.c.6548785.v1