Zobrazeno 1 - 10
of 308
pro vyhledávání: '"Ryoji, Nagai"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Advanced glycation end-products (AGEs) formation increases with metabolic disorders, leading to higher serum AGE levels in patients with progressive vascular complications. Measuring AGE levels in biological samples requires multiple pre-ana
Externí odkaz:
https://doaj.org/article/970bf2d445db4ead9d39dfde4b6398bf
Autor:
Keisuke Nakashima, Hiroyuki Miyashita, Hitoshi Yoshimitsu, Yukio Fujiwara, Ryoji Nagai, Tsuyoshi Ikeda
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Introduction: As inhibitors of advanced glycation end products (AGEs), such as pyridoxamine, significantly inhibit the development of retinopathy and neuropathy in rats with streptozotocin-induced diabetes, treatment with AGE inhibitors is believed t
Externí odkaz:
https://doaj.org/article/aa7e3efc2f3a42ba926eaa496c5c4c2d
Autor:
Kazuya Toriumi, Kyoka Iino, Azuna Ozawa, Mitsuhiro Miyashita, Syudo Yamasaki, Kazuhiro Suzuki, Hikari Sugawa, Koichi Tabata, Satoshi Yamaguchi, Satoshi Usami, Masanari Itokawa, Atsushi Nishida, Ryoji Nagai, Hidenori Kamiguchi, Makoto Arai
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102876- (2023)
Pentosidine (PEN) is an advanced glycation end-product (AGEs), where a fluorescent cross-link is formed between lysine and arginine residues in proteins. Accumulation of PEN is associated with aging and various diseases. We previously reported that a
Externí odkaz:
https://doaj.org/article/669484f5dbf847fe96284e5f9b8b22ea
Autor:
Masanori Itakura, Kosuke Yamaguchi, Roma Kitazawa, Sei-Young Lim, Yusuke Anan, Jun Yoshitake, Takahiro Shibata, Lumi Negishi, Hikari Sugawa, Ryoji Nagai, Koji Uchida
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Advanced glycation end products (AGEs) are believed to be pathogenic molecules that mediate pro-inflammatory responses. Here the authors identify histone as a cell-surface receptor for AGEs and show that AGEs may also be involved in the homeostatic r
Externí odkaz:
https://doaj.org/article/d003bd83c3e745449b35c8866cc7895f
Publikováno v:
Case Reports in Ophthalmological Medicine, Vol 2023 (2023)
Background. In recent years, immune checkpoint inhibitors (ICI) have been often used for several types of cancers. Immune-related adverse events (irAEs) are autoimmune responses caused by ICI. Among the different types of irAEs, uveitis is common in
Externí odkaz:
https://doaj.org/article/6f1ab560096149c089583e10b2f1739c
Autor:
Sho Osonoi, Hiroki Mizukami, Yuki Takeuchi, Hikari Sugawa, Saori Ogasawara, Shizuka Takaku, Takanori Sasaki, Kazuhiro Kudoh, Koichi Ito, Kazunori Sango, Ryoji Nagai, Yasuhiko Yamamoto, Makoto Daimon, Hiroshi Yamamoto, Soroku Yagihashi
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
It is suggested that activation of receptor for advanced glycation end products (RAGE) induces proinflammatory response in diabetic nerve tissues. Macrophage infiltration is invoked in the pathogenesis of diabetic polyneuropathy (DPN), while the asso
Externí odkaz:
https://doaj.org/article/8b94de940bb9438eb3a6b8cf190a6aa7
Autor:
Masao Jinno, Ryoji Nagai, Masayoshi Takeuchi, Aiko Watanabe, Koji Teruya, Hikari Sugawa, Naohisa Hatakeyama, Yuichi Jinno
Publikováno v:
Reproductive Biology and Endocrinology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Advanced glycation end-products (AGE), which accumulate with insulin resistance and aging, impair folliculogenesis and may decrease endometrial receptivity. Hishi (Trapa bispinosa Roxb.) extract, a safe herbal medicine, strongly i
Externí odkaz:
https://doaj.org/article/d0e5a313905e4b2bbb2ac0704e5b1796
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 72:147-156
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1224 (2022)
Advanced glycation end products (AGEs) are associated with diabetes and its complications. AGEs are formed by the non-enzymatic reactions of proteins and reducing sugars, such as glucose and ribose. Ribose is widely used in glycation research as it g
Externí odkaz:
https://doaj.org/article/ec436f503dd745b3ac33552955adda3d
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 70:256-261
Advanced glycation end products (AGEs), produced by the Maillard reaction between carbohydrates and proteins, may be involved in diabetes and its complications. Accurate quantification of AGEs