Zobrazeno 1 - 10
of 398
pro vyhledávání: '"Ryoichiro, Kageyama"'
Publikováno v:
Neuroscience Research, Vol 199, Iss , Pp 1-11 (2024)
SUMO (small ubiquitin-like modifier) conjugation or SUMOylation, a post-translational modification, is a crucial regulator of protein function and cellular processes. In the context of neural stem cells (NSCs), SUMOylation has emerged as a key player
Externí odkaz:
https://doaj.org/article/78029e4b75f24379bdfcf2e67a483568
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112520- (2023)
Summary: Oscillatory Hes1 expression activates cell proliferation, while high and sustained Hes1 expression induces quiescence, but the mechanism by which Hes1 differentially controls cell proliferation depending on its expression dynamics is unclear
Externí odkaz:
https://doaj.org/article/d659bf22a674419eb33df2f7163666c3
Autor:
Yujin Harada, Mayumi Yamada, Itaru Imayoshi, Ryoichiro Kageyama, Yutaka Suzuki, Takaaki Kuniya, Shohei Furutachi, Daichi Kawaguchi, Yukiko Gotoh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Adult neural stem cells are derived from an embryonic population of slowcycling progenitor cells, though how reduced cycling speed leads to establishment of the adult population has remained elusive. Here they show that non-oscillatory Notch-Hey sign
Externí odkaz:
https://doaj.org/article/ec6e527242f74785a99df676048fa5d1
Autor:
Yao Zhang, Ines Lahmann, Katharina Baum, Hiromi Shimojo, Philippos Mourikis, Jana Wolf, Ryoichiro Kageyama, Carmen Birchmeier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The cell source and dynamics of Notch ligands during the regulation of muscle stem cells is unclear. Here, the authors show that the Notch ligand Dll1 has to oscillate in order to control the balance between self-renewal and differentiation of muscle
Externí odkaz:
https://doaj.org/article/afeed375ae874570b42ac52637193643
Autor:
Jingtian Zhang, Junki Uchiyama, Koshi Imami, Yasushi Ishihama, Ryoichiro Kageyama, Taeko Kobayashi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Neural stem cell (NSC) quiescence plays pivotal roles in avoiding exhaustion of NSCs and securing sustainable neurogenesis in the adult brain. The maintenance of quiescence and transition between proliferation and quiescence are complex processes ass
Externí odkaz:
https://doaj.org/article/ca7cb6f4d83842bc9f362db59e4badb4
Autor:
Taeko Kobayashi, Wenhui Piao, Toshiya Takamura, Hiroshi Kori, Hitoshi Miyachi, Satsuki Kitano, Yumiko Iwamoto, Mayumi Yamada, Itaru Imayoshi, Seiji Shioda, Andrea Ballabio, Ryoichiro Kageyama
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
It remains unclear why quiescent neural stem cells (qNSCs) in the subventricular zone of the mouse brain have enlarged lysosomes. Here, authors demonstrate that qNSCs exhibit higher lysosomal activity and degrade activated EGF receptor by endolysosom
Externí odkaz:
https://doaj.org/article/4691a3fa38a34ed4b3aef31a73471536
Publikováno v:
eLife, Vol 9 (2020)
During vertebrate development, the presomitic mesoderm (PSM) periodically segments into somites, which will form the segmented vertebral column and associated muscle, connective tissue, and dermis. The periodicity of somitogenesis is regulated by a s
Externí odkaz:
https://doaj.org/article/a9567d5a2e0c48429f5c62601e1d3d35
Autor:
He Zhang, Ishii, Karan, Tatsuya Shibata, Shunsuke Ishii, Marika Hirao, Zhou Lu, Risa Takamura, Satsuki Kitano, Hitoshi Miyachi, Ryoichiro Kageyama, Eisuke Itakura, Taeko Kobayashi
Publikováno v:
Development (09501991); Feb2024, Vol. 151 Issue 4, p1-8, 8p
Autor:
He Zhang, Karan Ishii, Tatsuya Shibata, Shunsuke Ishii, Marika Hirao, Zhou Lu, Risa Takamura, Satsuki Kitano, Hitoshi Miyachi, Ryoichiro Kageyama, Eisuke Itakura, Taeko Kobayashi
Lysosomes are intracellular organelles responsible for degrading diverse macromolecules delivered from several pathways, such as the endo-lysosomal and autophagic pathways. Recent reports have suggested that lysosomes are essential in regulating neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0911c90439247b275e41b6bec75cc083
https://doi.org/10.1101/2023.05.12.540513
https://doi.org/10.1101/2023.05.12.540513
Autor:
Ryoichiro Kageyama
Publikováno v:
Nature. 611:671-673
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30dce0b4b002ae7a5a9378ea0ef5f51b
https://doi.org/10.1038/d41586-022-03562-2
https://doi.org/10.1038/d41586-022-03562-2