Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ryoichi X. Ioka"'
Autor:
Yuka Imamura Kawasawa, Hitoshi Teranishi, Toshihiro Suda, Masashi Yanagisawa, Akihiro Yamanaka, Ryoichi X. Ioka, Juro Sakai, Iori Sakakibara, Jian Xie, Saori Murakami, Kousaku Ohno, Takashi Ohuchi, Yukio Ikeda, Naoshi Dohmae, Toshiyuki Motoike, Haruhisa Iguchi, Takeshi Sakurai, Shinobu Takayasu, Satoshi Iwasaki, S. Clay Williams
Publikováno v:
Proceedings of the National Academy of Sciences. 103:7438-7443
Here, we report the isolation and characterization of an endogenous peptide ligand of GPR103 from rat brains. The purified peptide was found to be the 43-residue RF-amide peptide QRFP. We also describe two mouse homologues of human GPR103, termed mou
Autor:
Ryoichi X. Ioka, Shuying Jiang, Tatsuhiko Kodama, Timothy F. Osborne, Riuko Ohashi, Takashi Maejima, Yukio Ikeda, Juro Sakai, Haruhisa Iguchi, Koichi Sumi, Tokuo T. Yamamoto, Yasuyo Urashima, Masashi Yanagisawa, Hiroto Ohguchi, Noriaki Kojima, Masashi Okamura, Kenta Magoori, Satoshi Iwasaki, Shinobu Takayasu, Makoto Naito, Toshiya Tanaka, Aoi Uchida, Go Hasegawa
Publikováno v:
Journal of Biological Chemistry. 280:37669-37680
In obesity-related insulin resistance, pancreatic islets compensate for insulin resistance by increasing secretory capacity. Here, we report the identification of sex-determining region Y-box 6 (SOX6), a member of the high mobility group box superfam
Autor:
Masashi Yanagisawa, Toshiya Tanaka, Toshiyuki Mori, Satoshi Iwasaki, Kenta Magoori, Hiroshi Asaba, Sadayoshi Ito, Takahiro Fujino, Tatsuhiko Kodama, Tokuo T. Yamamoto, Yukio Ikeda, Sadao Takahashi, Joji Yamamoto, Ryoichi X. Ioka, Juro Sakai, Haruhisa Iguchi, Izumi W. Kaneko, Hiroshi Sakaue
Publikováno v:
Journal of Biological Chemistry. 279:16954-16962
Acetyl-CoA synthetase 2 (AceCS2) produces acetyl-CoA for oxidation through the citric acid cycle in the mitochondrial matrix. AceCS2 is highly expressed in the skeletal muscle and is robustly induced by fasting. Quantification of AceCS2 transcripts b
Autor:
Kenta Magoori, Man Jong Kang, Sadao Takahashi, Yuichiro Ito, Tokuo T. Yamamoto, Masako Sasaki, Akihisa Kamataki, Ryoichi X. Ioka, Takahiro Fujino, Shin Kamiyama, Dong Ho Kim, Yumiko A. Takei, Hironobu Sasano, Juro Sakai, Takashi Suzuki
Publikováno v:
Journal of Biological Chemistry. 278:7344-7349
By expression cloning using fluorescent-labeled high density lipoprotein (HDL), we isolated two clones that conferred the cell surface binding of HDL. Nucleotide sequence of the two clones revealed that one corresponds to scavenger receptor class B,
Autor:
Masashi Yanagisawa, Yoshiharu Miyamoto, Joji Yamamoto, Mitsuyo Okazaki, Katsumi Imaizumi, Shinichi Usui, Minoru Okubo, Takahiro Fujino, Hisashi Oishi, Yukio Ikeda, Masao Ono, Kenta Magoori, Hiroko Tomoyori, Hideyuki Sone, Sadao Takahashi, Shinji Takada, Masato Nose, Akihisa Kamataki, Hiroshi Asaba, Ryoichi X. Ioka, Juro Sakai, Toshio Murase, Dong Ho Kim, Tokuo T. Yamamoto, Man Jong Kang
Publikováno v:
Proceedings of the National Academy of Sciences. 100:229-234
A Wnt coreceptor low-density lipoprotein receptor-related protein 5 (LRP5) plays an essential role in bone accrual and eye development. Here, we show that LRP5 is also required for normal cholesterol and glucose metabolism. The production of mice lac
Autor:
Kenta Magoori, Dong Ho Kim, Takahiro Fujino, Yuko Cho, Qiong Liu, Shiroh Z. Yoshioka, Yousuke Inagaki, Takashi Suzuki, Hironobu Sasano, Man Jong Kang, Akira Nakano, Tokuo T. Yamamoto, Hiroyuki Suzuki, Ryoichi X. Ioka
Publikováno v:
Journal of Biochemistry. 124:1072-1076
The isolation and characterization of rabbit and human cDNAs revealed a new low density lipoprotein receptor (LDLR)-related protein (LRP) designated as LRP5. Human LRP5 cDNA encodes a 1, 616-amino acid type I membrane-like protein with three ligand b
Autor:
Masanori Nakata, Toshihiko Yada, Masashi Yanagisawa, Satoshi Iwasaki, Takeshi Sakurai, Tatsuhiko Kodama, Kenta Magoori, Yukio Ikeda, Haruhisa Iguchi, Tokuo T. Yamamoto, Juro Sakai, Shinobu Takayasu, Toshiya Tanaka, Ryoichi X. Ioka
Publikováno v:
Biochemical and biophysical research communications. 333(3)
The glucose-induced insulin secretion is fine-tuned by numerous factors. To systematically identify insulinotropic factors, we optimized a primary β-cell-based functional assay to monitor intracellular Ca2+ flux ([Ca2+]i). By this assay system, we s
Autor:
Takao Hamakubo, Kenta Magoori, Johan Auwerx, Koichi Sumi, Satoshi Iwasaki, Yasutoshi Uchiyama, Yukio Ikeda, Tatsuhiko Kodama, Juro Sakai, Keisuke Tachibana, Takefumi Doi, Masashi Yanagisawa, Hiroshi Asaba, Hiroki Hamura, Ryoichi X. Ioka, Haruhisa Iguchi, Makoto Naito, Yuichiro Watanabe, Joji Yamamoto, Toshiya Tanaka, Mitsuhiro Watanabe, Sadayoshi Ito
In this study, we defined the role of peroxisome proliferator-activated receptor β/δ (PPARδ) in metabolic homeostasis by using subtype selective agonists. Analysis of rat L6 myotubes treated with the PPARδ subtype-selective agonist, GW501516, by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1468df9c890296bac4a73959f643aa
https://europepmc.org/articles/PMC307669/
https://europepmc.org/articles/PMC307669/
Autor:
Shinichi Usui, Masao Ono, Kenta Magoori, Takahiro Fujino, Mitsuko R. Ito, Man Jong Kang, Sadao Takahashi, Satoshi Iwasaki, Ryoichi X. Ioka, Tokuo T. Yamamoto, Masako Sasaki, Juro Sakai, Yumiko A. Takei, Mitsuyo Okazaki, Hiroshi Asaba, Hajime Kakuuchi, Masato Nose, Akihisa Kamataki, Dong Ho Kim
Publikováno v:
The Journal of biological chemistry. 278(13)
LDL receptor-related protein 5 (LRP5) plays multiple roles, including embryonic development and bone accrual development. Recently, we demonstrated that LRP5 is also required for normal cholesterol metabolism and glucose-induced insulin secretion. To
Autor:
Akira Nakano, Kenta Magoori, Qiong Liu, Ryoichi X. Ioka, Takahiro Fujino, Man-Jong Kang, Yousuke Inagaki, Yuko Cho, Shiroh Z. Yoshioka, Tokuo T. Yamamoto, Dong Ho Kim
Publikováno v:
Lipoprotein Metabolism and Atherogenesis ISBN: 9784431684268
Two apolipoprotein E (apoE) specific receptors, designated as ‘very low density lipoprotein receptor’ (VLDLR) and ‘apoE receptor 2’ (apoER2), closely resemble the structure of the low density lipoprotein receptor (LDLR), but they are expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e894cc2fed2eb6a800ad8d6cf029ab7d
https://doi.org/10.1007/978-4-431-68424-4_23
https://doi.org/10.1007/978-4-431-68424-4_23