Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ryoichi, Ohtsuka"'
Autor:
Sousuke Masuda, Robert R. Maronpot, Misato Nakamura, Shim-mo Hayashi, Mari Inohana, Suzuka Uomoto, Emi Makino, Hirotada Murayama, Rei Nagahara, Toshinori Yoshida, Sayaka Mizukami, Masashi Kawashima, Makoto Shibutani, Mio Kobayashi, Ayumi Eguchi, Risako Yamashita, Ryoichi Ohtsuka, Naofumi Takahashi
Publikováno v:
Environmental Science and Pollution Research. 29:779-789
Nonalcoholic fatty liver disease is a hepatic disorder with deposition of fat droplets, and has a high risk of progression to steatosis-related hepatitis and irreversible hepatic cancer. Metronidazole (MNZ) is an antiprotozoal and antimicrobial agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb96643f2aca4be6e9922a13f98f45e
https://doi.org/10.1007/s11356-021-15689-2
https://doi.org/10.1007/s11356-021-15689-2
Autor:
Naofumi Takahashi, Yuko Watanabe, Hitoshi Tajima, Ryoichi Ohtsuka, Yoshimasa Okazaki, Risako Tajiki-Nishino, Tomoki Fukuyama, Emi Makino, Aya Ohnuma-Koyama
Publikováno v:
The Journal of Nutritional Biochemistry. 67:14-19
Folic acid (FA) deficiency is associated with several health problems, including megaloblastic anemia and fetal neural tube defects. Therefore, supplementation with FA is strongly recommended by governments worldwide. Recent published reports indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c57363112930ce236fc0e6c133a8b02
https://doi.org/10.1016/j.jnutbio.2019.01.009
https://doi.org/10.1016/j.jnutbio.2019.01.009
Autor:
Toshinori Yoshida, Masahi Kawashima, Ryoichi Ohtsuka, Sayaka Mizukami, Ayumi Eguchi, Emi Makino, Rei Nagahara, Mihoko Koyanagi, Hirotada Murayama, Makoto Shibutani, Misato Nakamura, Masayuki Kimura, Robert R. Maronpot, Shim-mo Hayashi, Naofumi Takahashi
Publikováno v:
Toxicologic Pathology. 46:530-539
Administration of the diuretic, spironolactone (SR), can inhibit chronic liver diseases. We determined the effects of SR alone or in combination with the antioxidant α-glycosyl isoquercitrin (AGIQ) on hyperlipidemia- and steatosis-related precancero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f47887b932e23a584baefc5a8edb2e
https://doi.org/10.1177/0192623318778508
https://doi.org/10.1177/0192623318778508
Autor:
Satoru Yamaguchi, Takanori Harada, Toshinori Yoshida, Makio Takeda, Tadashi Kosaka, Ryoichi Ohtsuka, Naofumi Takahashi, Sayuri Kojima
Publikováno v:
Toxicologic pathology. 46(3)
Chromated copper arsenate (CCA) is used as a wood preservative worldwide. Exposure to it may adversely affect human health. Some events have increased human exposure to CCA, including the Great East Japan Earthquake, which generated a large amount of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2591e21e1cf13192256b17cbb837644
https://pubmed.ncbi.nlm.nih.gov/29587599
https://pubmed.ncbi.nlm.nih.gov/29587599
Autor:
Makio Takeda, Aya Ohnuma-Koyama, Mariko Tomita, Tomoki Fukuyama, Ryoichi Ohtsuka, Satoru Yamaguchi, Nobuaki Nakashima, Toshinori Yoshida, Maki Kuwahara, Takanori Harada, Sayuri Kojima, Naofumi Takahashi, Junko Fukumori, Yukiko Takeuchi-Kashimoto, Tadashi Kosaka
Publikováno v:
The Journal of Toxicological Sciences. 38:775-782
Emerging evidence suggests that chronic exposure to DDT and its derivatives is associated with a variety of human disorders such as anemia. The present study demonstrated that p,p'-DDT caused microcystic anemia in a dose-dependent manner (0, 5, 50, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50391d7731d4a8596756389e7be21784
https://doi.org/10.2131/jts.38.775
https://doi.org/10.2131/jts.38.775
Autor:
Maki Kuwahara, Yukiko Takeuchi, Sayuri Kojima, Junya Sasaki, Naofumi Takahashi, Koichi Hayashi, Toshinori Yoshida, Mariko Tomita, Tomoki Fukuyama, Tadashi Kosaka, Haruka Tajima, Makio Takeda, Nobuaki Nakashima, Aya Ohnuma, Takanori Harada, Junko Fukumori, Satoru Yamaguchi, Ryoichi Ohtsuka
Publikováno v:
Experimental and Toxicologic Pathology. 62:643-651
Didecyldimethylammonium chloride (DDAC) is used worldwide as a germicide, in antiseptics, and as a wood preservative, and can cause adverse pulmonary disease in humans. However, the pulmonary toxicity of DDAC has not yet been thoroughly investigated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3216d829e17947f88bf403f03f661f
https://doi.org/10.1016/j.etp.2009.08.007
https://doi.org/10.1016/j.etp.2009.08.007
Autor:
Keizo Maita, Yasufumi Shutoh, Makio Takeda, Yutaka Komatsu, Atsuko Haishima, Takanori Harada, Ryoichi Ohtsuka, Hideaki Fujie, Satoru Yamaguchi
Publikováno v:
The Journal of Toxicological Sciences. 34:469-482
To verify the relationship between oxidative stress and DNA methylation in the young brain, dichlorodiphenyltrichloroethane (DDT) was administered by gavage to male young rats at doses of 0, 0.006, 0.06, 0.6, 6, and 60 mg/kg/day for a period of 4 wee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440736a4ee8b3b76255b2f1d0b964d01
https://doi.org/10.2131/jts.34.469
https://doi.org/10.2131/jts.34.469
Autor:
Takanori Harada, Toshinori Yoshida, Makio Takeda, Sayuri Kojima, Akiko Enomoto, Ryoichi Ohtsuka, Nobuaki Nakashima, Masakazu Ozaki, Naruto Tomiyama
Publikováno v:
Journal of Toxicologic Pathology. 19:155-167
DDT is known as a nongenotoxic hepatocarcinogen and has been shown to induce microsomal enzymes and GGT-positive foci and to inhibit gap junctional intercellular communication (GJIC) in the rodent liver. In consideration of these findings, we examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72e71e40bff4d1ad13404ae1db6171c2
https://doi.org/10.1293/tox.19.155
https://doi.org/10.1293/tox.19.155
Autor:
Junya Sasaki, Toshinori Yoshida, Tadashi Kosaka, Yukiko Takeuchi, Yuko Chiba, Keizo Maita, Makio Takeda, Sayuri Kojima, Ryoichi Ohtsuka, Sayaka Ishimine, Takanori Harada, Maki Kuwahara, Naofumi Takahashi, Koichi Hayashi
Publikováno v:
Journal of Toxicologic Pathology. 18:89-98
We previously demonstrated that rat offspring exposed perinatally to methoxychlor (MXC) still exhibited immunotoxic changes in young adulthood at 10 weeks of age. That result led us to further investigate whether the influence of perinatal exposure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b578d4d3090f2e971df3b3a455afc081
https://doi.org/10.1293/tox.18.89
https://doi.org/10.1293/tox.18.89
Autor:
Toshinori Yoshida, Makio Takeda, Ryoichi Ohtsuka, Maki Kuwahara, Keizo Maita, Naofumi Takahashi, Yukiko Takeuchi, Yuko Chiba, Koichi Hayashi, Takanori Harada, Tadashi Kosaka, Sayaka Ishimine
Publikováno v:
Journal of Toxicologic Pathology. 17:165-170
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0300d53b33f7861fe6efa28c58ee63cf
https://doi.org/10.1293/tox.17.165
https://doi.org/10.1293/tox.17.165