Zobrazeno 1 - 10
of 306
pro vyhledávání: '"Ryohei NISHIMURA"'
Autor:
Kosei Ishimaru, Masataka Ikeda, Hiroko Deguchi Miyamoto, Shun Furusawa, Ko Abe, Masatsugu Watanabe, Takuya Kanamura, Satoshi Fujita, Ryohei Nishimura, Takayuki Toyohara, Shouji Matsushima, Tomoko Koumura, Ken‐ichi Yamada, Hirotaka Imai, Hiroyuki Tsutsui, Tomomi Ide
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 1 (2024)
Background Ferroptosis, an iron‐dependent form of regulated cell death, is a major cell death mode in myocardial ischemia reperfusion (I/R) injury, along with mitochondrial permeability transition‐driven necrosis, which is inhibited by cyclospori
Externí odkaz:
https://doaj.org/article/dbaf2db9f0a143d98668818ad9250cb5
Autor:
Naoki Fujita, Fumi Sugiyama, Masaya Tsuboi, Hazel Kay Nakamura, Ryohei Nishimura, Yasuhide Nakayama, Atsushi Fujita
Publikováno v:
Bioengineering, Vol 11, Iss 6, p 615 (2024)
Urinary tract diseases are common in cats, and often require surgical reconstruction. Here, to explore the possibility of urinary tract reconstruction in cats using in-body tissue architecture (iBTA), biosheets fabricated using iBTA technology were i
Externí odkaz:
https://doaj.org/article/5e90954405b9469baf0065c8a36f4c2a
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Dying or damaged cells that are not completely eradicated by the immune system release their intracellular components in the extracellular space. Aberrant exposure of the damage-associated molecules to the immune system is often associated w
Externí odkaz:
https://doaj.org/article/22d60bea34a74a2f9e372f6b97c7a09b
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract In the majority of spinal cord injury (SCI) patients, spasticity develops in the subacute phase and chronically persists with muscle hypertonia. Among various pathological conditions underlying spasticity, upregulated expression of 5-HT rece
Externí odkaz:
https://doaj.org/article/f69cb93e96a341c7a8c62d60adc9ad1c
Autor:
Tomoki Motegi, Takayuki Nakagawa, Shingo Maeda, Aki Iio, Kenjiro Kaji, Yuko Goto-Koshino, Shotaro Eto, Namiko Ikeda, Ryohei Nishimura, Tomohiro Yonezawa, Yasuyuki Momoi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background Targeting regulatory T cell (Treg) infiltration is an emerging strategy for cancer immunotherapy. However, its efficacy in advanced prostate cancer remains unclear. Here, we showed the therapeutic efficacy of anti-Treg treatment in a canin
Externí odkaz:
https://doaj.org/article/a31d4e8d108b4347a9e966ac1b63ac80
Autor:
Akihito Ishikita, Shouji Matsushima, Soichiro Ikeda, Kosuke Okabe, Ryohei Nishimura, Tomonori Tadokoro, Nobuyuki Enzan, Taishi Yamamoto, Masashi Sada, Yoshitomo Tsutsui, Ryo Miyake, Masataka Ikeda, Tomomi Ide, Shintaro Kinugawa, Hiroyuki Tsutsui
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103517- (2021)
Summary: Molecular mechanisms mediating cardiac hypertrophy by glucose metabolism are incompletely understood. Hexosamine biosynthesis pathway (HBP), an accessory pathway of glycolysis, is known to be involved in the attachment of O-linked N-acetylgl
Externí odkaz:
https://doaj.org/article/1a1423f963444dff93d60619b505cc28
Autor:
Yukina Kuwahara, Karin Yoshizaki, Hidetaka Nishida, Hiroaki Kamishina, Sadatoshi Maeda, Katsura Takano, Naoki Fujita, Ryohei Nishimura, Jun-ichiro Jo, Yasuhiko Tabata, Hideo Akiyoshi
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Mesenchymal stem/stromal cells (MSCs) have been used as cell sources for treating dogs with naturally-occurring diseases. Extracellular vesicles (EVs) derived from MSCs are now recognized as pivotal to modulating the immune response and supporting ti
Externí odkaz:
https://doaj.org/article/31b57afb2ec24aea87f60f7b4e802389
Autor:
Daiki Kato, Tomonori Yaguchi, Takashi Iwata, Yuki Katoh, Kenji Morii, Kinya Tsubota, Yoshiaki Takise, Masaki Tamiya, Haruhiko Kamada, Hiroki Akiba, Kouhei Tsumoto, Satoshi Serada, Tetsuji Naka, Ryohei Nishimura, Takayuki Nakagawa, Yutaka Kawakami
Publikováno v:
eLife, Vol 9 (2020)
Current xenogeneic mouse models cannot evaluate on-target off-tumor adverse effect, hindering the development of chimeric antigen receptor (CAR) T cell therapies for solid tumors, due to limited human/mouse cross-reactivity of antibodies used in CAR
Externí odkaz:
https://doaj.org/article/d030ebf95bdf404e87e0c8329118623a
Autor:
Sho Yoshimoto, Daiki Kato, Satoshi Kamoto, Kie Yamamoto, Masaya Tsuboi, Masahiro Shinada, Namiko Ikeda, Yuiko Tanaka, Ryohei Yoshitake, Shotaro Eto, Kohei Saeki, James Chambers, Ryohei Kinoshita, Kazuyuki Uchida, Ryohei Nishimura, Takayuki Nakagawa
Publikováno v:
Heliyon, Vol 5, Iss 7, Pp e02004- (2019)
The human epidermal growth factor receptor 2 (HER2) is expressed in various human cancers including thyroid cancers (TC) and is used as a diagnostic marker and therapeutic target. Canine TC (cTC), the most common endocrine malignancy in dogs, shows a
Externí odkaz:
https://doaj.org/article/c826c08557774a318c223e2cf03be560
Autor:
Shotaro Eto, Kohei Saeki, Ryohei Yoshitake, Sho Yoshimoto, Masahiro Shinada, Namiko Ikeda, Satoshi Kamoto, Yuiko Tanaka, Daiki Kato, Shingo Maeda, Masaya Tsuboi, James Chambers, Kazuyuki Uchida, Ryohei Nishimura, Takayuki Nakagawa
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218382 (2019)
Canine urothelial carcinoma (cUC) is the most common tumor of the lower urinary tract in dogs. Although chemotherapy and radical surgery have improved the overall survival, most dogs with cUC succumb to metastasis or recurrence. Therefore, the develo
Externí odkaz:
https://doaj.org/article/74e82af3ac9642e29d29432edaf683fa